FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4200580425> ?p ?o ?g. }

• W4200580425 abstract "Abstract Background Achondroplasia is the most common genetic skeletal disorder causing disproportionate short stature/dwarfism. Common additional features include spinal stenosis, midface retrusion, macrocephaly and a generalized spondylometaphyseal dysplasia which manifest as spinal cord compression, sleep disordered breathing, delayed motor skill acquisition and genu varus with musculoskeletal pain. To better understand the interactions and health outcomes of these potential complications, we embarked on a multi-center, natural history study entitled CLARITY (achondroplasia natural history study). One of the CLARITY objectives was to develop growth curves (length/height, weight, head circumference, weight-for-height) and corresponding reference tables of mean and standard deviations at 1 month increments from birth through 18 years for clinical use and research for achondroplasia patients. Methods All available retrospective anthropometry data including length/height, weight and head circumference from achondroplasia patients were collected at 4 US skeletal dysplasia centers (Johns Hopkins University, AI DuPont Hospital for Children, McGovern Medical School University of Texas Health, University of Wisconsin School of Medicine and Public Health). Weight-for-age values beyond 3 SD above the mean were excluded from the weight-for-height and weight-for-age curves to create a stricter tool for weight assessment in this population. Results Over 37,000 length/height, weight and head circumference measures from 1374 patients with achondroplasia from birth through 75 years of age were compiled in a REDCap database. Stature and weight data from birth through 18 years of age and head circumference from birth through 5 years of age were utilized to construct new length/height-for-age, weight-for-age, head circumference-for-age and weight-for-height curves. Conclusion Achondroplasia-specific growth curves are essential for clinical care of growing infants and children with this condition. In an effort to provide prescriptive, rather than purely descriptive, references for weight in this population, extreme weight values were omitted from the weight-for-age and weight-for-height curves. This well-phenotyped cohort may be studied with other global achondroplasia populations (e.g. Europe, Argentina, Australia, Japan) to gain further insight into environmental or ethnic influences on growth." @default.
• W4200580425 created "2021-12-31" @default.
• W4200580425 creator A5005059491 @default.
• W4200580425 creator A5009685036 @default.
• W4200580425 creator A5021055370 @default.
• W4200580425 creator A5025738803 @default.
• W4200580425 creator A5028724151 @default.
• W4200580425 creator A5030596121 @default.
• W4200580425 creator A5033079105 @default.
• W4200580425 creator A5053470386 @default.
• W4200580425 creator A5058824970 @default.
• W4200580425 creator A5060415374 @default.
• W4200580425 creator A5065772307 @default.
• W4200580425 creator A5069723095 @default.
• W4200580425 creator A5070100761 @default.
• W4200580425 creator A5076103156 @default.
• W4200580425 creator A5081107220 @default.
• W4200580425 creator A5086842442 @default.
• W4200580425 date "2021-12-01" @default.
• W4200580425 modified "2023-10-11" @default.
• W4200580425 title "Growth in achondroplasia including stature, weight, weight-for-height and head circumference from CLARITY: achondroplasia natural history study—a multi-center retrospective cohort study of achondroplasia in the US" @default.
• W4200580425 cites W1525114242 @default.
• W4200580425 cites W1578457266 @default.
• W4200580425 cites W1845799850 @default.
• W4200580425 cites W1961665900 @default.
• W4200580425 cites W1989356167 @default.
• W4200580425 cites W2005453160 @default.
• W4200580425 cites W2058809573 @default.
• W4200580425 cites W2059949919 @default.
• W4200580425 cites W2065722407 @default.
• W4200580425 cites W2071639782 @default.
• W4200580425 cites W2074045429 @default.
• W4200580425 cites W2093274439 @default.
• W4200580425 cites W2094449106 @default.
• W4200580425 cites W2145860140 @default.
• W4200580425 cites W2156266702 @default.
• W4200580425 cites W2162343930 @default.
• W4200580425 cites W2397011745 @default.
• W4200580425 cites W2437675304 @default.
• W4200580425 cites W2604331532 @default.
• W4200580425 cites W2613371230 @default.
• W4200580425 cites W2624274779 @default.
• W4200580425 cites W2788064418 @default.
• W4200580425 cites W2885242166 @default.
• W4200580425 cites W2889180617 @default.
• W4200580425 cites W2923718588 @default.
• W4200580425 cites W2997610919 @default.
• W4200580425 cites W2999797567 @default.
• W4200580425 cites W3112717819 @default.
• W4200580425 cites W3135630188 @default.
• W4200580425 cites W3161656822 @default.
• W4200580425 doi "https://doi.org/10.1186/s13023-021-02141-4" @default.
• W4200580425 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34949201" @default.
• W4200580425 hasPublicationYear "2021" @default.
• W4200580425 type Work @default.
• W4200580425 citedByCount "10" @default.
• W4200580425 countsByYear W42005804252022 @default.
• W4200580425 countsByYear W42005804252023 @default.
• W4200580425 crossrefType "journal-article" @default.
• W4200580425 hasAuthorship W4200580425A5005059491 @default.
• W4200580425 hasAuthorship W4200580425A5009685036 @default.
• W4200580425 hasAuthorship W4200580425A5021055370 @default.
• W4200580425 hasAuthorship W4200580425A5025738803 @default.
• W4200580425 hasAuthorship W4200580425A5028724151 @default.
• W4200580425 hasAuthorship W4200580425A5030596121 @default.
• W4200580425 hasAuthorship W4200580425A5033079105 @default.
• W4200580425 hasAuthorship W4200580425A5053470386 @default.
• W4200580425 hasAuthorship W4200580425A5058824970 @default.
• W4200580425 hasAuthorship W4200580425A5060415374 @default.
• W4200580425 hasAuthorship W4200580425A5065772307 @default.
• W4200580425 hasAuthorship W4200580425A5069723095 @default.
• W4200580425 hasAuthorship W4200580425A5070100761 @default.
• W4200580425 hasAuthorship W4200580425A5076103156 @default.
• W4200580425 hasAuthorship W4200580425A5081107220 @default.
• W4200580425 hasAuthorship W4200580425A5086842442 @default.
• W4200580425 hasBestOaLocation W42005804251 @default.
• W4200580425 hasConcept C126322002 @default.
• W4200580425 hasConcept C1862650 @default.
• W4200580425 hasConcept C187212893 @default.
• W4200580425 hasConcept C2777871287 @default.
• W4200580425 hasConcept C2780472190 @default.
• W4200580425 hasConcept C61427482 @default.
• W4200580425 hasConcept C71924100 @default.
• W4200580425 hasConceptScore W4200580425C126322002 @default.
• W4200580425 hasConceptScore W4200580425C1862650 @default.
• W4200580425 hasConceptScore W4200580425C187212893 @default.
• W4200580425 hasConceptScore W4200580425C2777871287 @default.
• W4200580425 hasConceptScore W4200580425C2780472190 @default.
• W4200580425 hasConceptScore W4200580425C61427482 @default.
• W4200580425 hasConceptScore W4200580425C71924100 @default.
• W4200580425 hasFunder F4320310557 @default.
• W4200580425 hasIssue "1" @default.
• W4200580425 hasLocation W42005804251 @default.
• W4200580425 hasLocation W42005804252 @default.
• W4200580425 hasLocation W42005804253 @default.
• W4200580425 hasLocation W42005804254 @default.
• W4200580425 hasOpenAccess W4200580425 @default.
• W4200580425 hasPrimaryLocation W42005804251 @default.
• W4200580425 hasRelatedWork W1527225067 @default.
• W4200580425 hasRelatedWork W2015560438 @default.

• next