Matches in SemOpenAlex for { <https://semopenalex.org/work/W4200587905> ?p ?o ?g. }
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- W4200587905 startingPage "74" @default.
- W4200587905 abstract "Protein ubiquitination is a key post-translational modification in regulating many fundamental cellular processes and dysregulation of these processes can give rise to a vast array of diseases. Unravelling the molecular mechanisms of ubiquitination hence is an important area in current ubiquitin research with as aim to understand this enigmatic process. The complexity of ubiquitin (Ub) signaling arises from the large variety of Ub conjugates, where Ub is attached to other Ub proteins, Ub-like proteins, and protein substrates. The chemical preparation of such Ub conjugates in high homogeneity and in adequate amounts contributes greatly to the deciphering of Ub signaling. The strength of these chemically synthesized conjugates lies in the chemo-selectivity in which they can be created that are sometimes difficult to obtain using biochemical methodology. In this review, we will discuss the progress in the chemical protein synthesis of state-of-the-art Ub and Ub-like chemical probes, their unique concepts and related discoveries in the ubiquitin field." @default.
- W4200587905 created "2021-12-31" @default.
- W4200587905 creator A5060430222 @default.
- W4200587905 creator A5080047287 @default.
- W4200587905 date "2022-12-01" @default.
- W4200587905 modified "2023-10-09" @default.
- W4200587905 title "State of the art in (semi-)synthesis of Ubiquitin- and Ubiquitin-like tools" @default.
- W4200587905 cites W1764025554 @default.
- W4200587905 cites W1968652549 @default.
- W4200587905 cites W1970108447 @default.
- W4200587905 cites W1971190621 @default.
- W4200587905 cites W1974389826 @default.
- W4200587905 cites W1978135217 @default.
- W4200587905 cites W1979584856 @default.
- W4200587905 cites W1986317046 @default.
- W4200587905 cites W1994819844 @default.
- W4200587905 cites W1996703055 @default.
- W4200587905 cites W2001234769 @default.
- W4200587905 cites W2006328781 @default.
- W4200587905 cites W2023195415 @default.
- W4200587905 cites W2028157992 @default.
- W4200587905 cites W2030609318 @default.
- W4200587905 cites W2030818842 @default.
- W4200587905 cites W2035151409 @default.
- W4200587905 cites W2049335132 @default.
- W4200587905 cites W2049748848 @default.
- W4200587905 cites W2058666659 @default.
- W4200587905 cites W2061252639 @default.
- W4200587905 cites W2063056394 @default.
- W4200587905 cites W2085392012 @default.
- W4200587905 cites W2095112394 @default.
- W4200587905 cites W2096569452 @default.
- W4200587905 cites W2099464495 @default.
- W4200587905 cites W2099598643 @default.
- W4200587905 cites W2101090646 @default.
- W4200587905 cites W2101369857 @default.
- W4200587905 cites W2108762552 @default.
- W4200587905 cites W2110960544 @default.
- W4200587905 cites W2111385909 @default.
- W4200587905 cites W2116179149 @default.
- W4200587905 cites W2118225942 @default.
- W4200587905 cites W2119048511 @default.
- W4200587905 cites W2119697806 @default.
- W4200587905 cites W2120504689 @default.
- W4200587905 cites W2134578763 @default.
- W4200587905 cites W2136506445 @default.
- W4200587905 cites W2141808578 @default.
- W4200587905 cites W2143161083 @default.
- W4200587905 cites W2144114582 @default.
- W4200587905 cites W2147917253 @default.
- W4200587905 cites W2154623708 @default.
- W4200587905 cites W2158359547 @default.
- W4200587905 cites W2167475134 @default.
- W4200587905 cites W2169018921 @default.
- W4200587905 cites W2170503582 @default.
- W4200587905 cites W2225702737 @default.
- W4200587905 cites W2291388628 @default.
- W4200587905 cites W2307933984 @default.
- W4200587905 cites W2309125062 @default.
- W4200587905 cites W2317758348 @default.
- W4200587905 cites W2318667448 @default.
- W4200587905 cites W2327328750 @default.
- W4200587905 cites W2328753773 @default.
- W4200587905 cites W2334429056 @default.
- W4200587905 cites W2400942913 @default.
- W4200587905 cites W2408652949 @default.
- W4200587905 cites W2559824970 @default.
- W4200587905 cites W2582931844 @default.
- W4200587905 cites W2586326639 @default.
- W4200587905 cites W2596491515 @default.
- W4200587905 cites W2607310043 @default.
- W4200587905 cites W2613065881 @default.
- W4200587905 cites W2751521307 @default.
- W4200587905 cites W2757682641 @default.
- W4200587905 cites W2766422151 @default.
- W4200587905 cites W2767488222 @default.
- W4200587905 cites W2767848355 @default.
- W4200587905 cites W2769933221 @default.
- W4200587905 cites W2775756091 @default.
- W4200587905 cites W2793986986 @default.
- W4200587905 cites W2803389628 @default.
- W4200587905 cites W2891413280 @default.
- W4200587905 cites W2907203083 @default.
- W4200587905 cites W2915061592 @default.
- W4200587905 cites W2939740960 @default.
- W4200587905 cites W2946238702 @default.
- W4200587905 cites W2949015502 @default.
- W4200587905 cites W2966295412 @default.
- W4200587905 cites W2971941127 @default.
- W4200587905 cites W2976861250 @default.
- W4200587905 cites W2982620886 @default.
- W4200587905 cites W2984350850 @default.
- W4200587905 cites W2995287030 @default.
- W4200587905 cites W3002137793 @default.
- W4200587905 cites W3007771926 @default.
- W4200587905 cites W3012782066 @default.
- W4200587905 cites W3017056382 @default.
- W4200587905 cites W3019843025 @default.