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• W4200588917 abstract "ABSTRACT Background Despite an increased cancer risk for patients with chronic kidney disease (CKD), uptake of cancer screening varies due to competing priorities and complex health-related issues. This study aimed to elicit the preferences and important attributes of cancer screening in patients with CKD. Methods An on-line best–worst scaling survey was used to ascertain the relative importance of 22 screening attributes among CKD patients using an incomplete block design. Preference scores (0–1) were calculated by multinomial logistic regression. Preference heterogeneity was evaluated. Results The survey was completed by 83 patients: 26 not requiring kidney replacement therapy, 20 receiving dialysis and 37 transplant recipients (mean age 59 years, 53% men, 75% prior to cancer screening). The five most important attributes were early detection {preference score 1.0 [95% confidence interval (CI) 0.90–1.10]}, decreased risk of cancer death [0.85 (0.75–0.94)], false negatives [0.71 (0.61–0.80)], reduction in immunosuppression if detected [0.68 (0.59–0.78)] and non-invasive interventions after positive results [0.68 (0.59–0.78)]. Preference heterogeneity reflected the stage of CKD. Immunosuppression reduction [mean difference 0.11 (95% CI 0.02–0.19)] and views of family/friends [0.10 (reference attribute)] were important for transplant recipients. Screening frequency [−0.18 (95% CI −0.26 to −0.10)] and overdiagnosis of harmless cancers [−0.14 (95% CI −0.22 to −0.10)] were important for dialysis patients. Conclusion Early detection, risk of cancer-related death, false negatives, immunosuppression reduction and non-invasive interventions following detection are important cancer screening considerations among CKD patients. Patient preferences are key to shared decision-making and individualized cancer screening." @default.
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• W4200588917 date "2021-12-27" @default.
• W4200588917 modified "2023-10-12" @default.
• W4200588917 title "Patient preferences for cancer screening in chronic kidney disease: a best–worst scaling survey" @default.
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• W4200588917 doi "https://doi.org/10.1093/ndt/gfab360" @default.
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