Matches in SemOpenAlex for { <https://semopenalex.org/work/W4200604834> ?p ?o ?g. }
Showing items 1 to 93 of
93
with 100 items per page.
- W4200604834 endingPage "S259" @default.
- W4200604834 startingPage "S258" @default.
- W4200604834 abstract "Uncontrolled gestational diabetes mellitus (GDM) is associated with severe maternal and neonatal morbidities. Probiotic supplements were shown to modulate the gut microbiome. Promising effects on glycemic control and insulin resistance in non-pregnant diabetic patients were reported. However, the effect of probiotics on glycemic control in GDM has not been elucidated. We aimed to examine the effect of a mixture of probiotic strains given daily on maternal glycemic parameters, and pregnancy outcomes among women with GDM. A multicenter prospective randomized, double blind, placebo controlled trial was conducted at five medical centers between January 2020 and June 2021. Women newly diagnosed with GDM were divided into a research group, receiving 2 capsules of oral probiotic formula containing Bifidobacterium bifidum, Bifidobacterium lactis, Lactobacillus (L) acidophilus, L. paracasei, L. rhamnosus and Streptococcus thermophilus ( >6X109/capsule), and a control group, receiving a placebo (2 capsules/day) until delivery. Glycemic control was evaluated by daily glucose charts. After 2 weeks, pharmacotherapy was started in case of poor glycemic control defined as either mean daily glucose >100 mg/dL or more than 20% abnormal glucose values. The primary outcomes were the rate of women requiring medications for glycemic control and mean daily glucose charts after 2 weeks of treatment with the study products. In order to show a reduction of the need for pharmacotherapy for GDM from 60% to 30%, 84 women were required (5% two tailed alpha, 80% power). This sample size was sufficient to demonstrate a mean difference of 6±10 mg/dL in the mean daily glucose charts after 2 weeks of treatment with the study products. Forty one and 44 women were analyzed in the treatment and placebo cohorts, respectively. Baseline characteristics were comparable between the groups (table 1). There was no difference in glycemic control between the groups (table 2). The oral probiotic product tested in this study did not affect glycemic control of women with GDM.View Large Image Figure ViewerDownload Hi-res image Download (PPT)" @default.
- W4200604834 created "2021-12-31" @default.
- W4200604834 creator A5011648508 @default.
- W4200604834 creator A5012606869 @default.
- W4200604834 creator A5015950144 @default.
- W4200604834 creator A5026706566 @default.
- W4200604834 creator A5038763602 @default.
- W4200604834 creator A5040538877 @default.
- W4200604834 creator A5052820854 @default.
- W4200604834 creator A5055045172 @default.
- W4200604834 creator A5058532803 @default.
- W4200604834 creator A5060458203 @default.
- W4200604834 creator A5062999245 @default.
- W4200604834 creator A5078632579 @default.
- W4200604834 date "2022-01-01" @default.
- W4200604834 modified "2023-09-24" @default.
- W4200604834 title "The effect of probiotics on glycemic control of women with gestational diabetes mellitus-multicenter, randomized, double blind, placebo controlled-trial" @default.
- W4200604834 doi "https://doi.org/10.1016/j.ajog.2021.11.098" @default.
- W4200604834 hasPublicationYear "2022" @default.
- W4200604834 type Work @default.
- W4200604834 citedByCount "0" @default.
- W4200604834 crossrefType "journal-article" @default.
- W4200604834 hasAuthorship W4200604834A5011648508 @default.
- W4200604834 hasAuthorship W4200604834A5012606869 @default.
- W4200604834 hasAuthorship W4200604834A5015950144 @default.
- W4200604834 hasAuthorship W4200604834A5026706566 @default.
- W4200604834 hasAuthorship W4200604834A5038763602 @default.
- W4200604834 hasAuthorship W4200604834A5040538877 @default.
- W4200604834 hasAuthorship W4200604834A5052820854 @default.
- W4200604834 hasAuthorship W4200604834A5055045172 @default.
- W4200604834 hasAuthorship W4200604834A5058532803 @default.
- W4200604834 hasAuthorship W4200604834A5060458203 @default.
- W4200604834 hasAuthorship W4200604834A5062999245 @default.
- W4200604834 hasAuthorship W4200604834A5078632579 @default.
- W4200604834 hasBestOaLocation W42006048341 @default.
- W4200604834 hasConcept C126322002 @default.
- W4200604834 hasConcept C134018914 @default.
- W4200604834 hasConcept C142724271 @default.
- W4200604834 hasConcept C168563851 @default.
- W4200604834 hasConcept C204787440 @default.
- W4200604834 hasConcept C27081682 @default.
- W4200604834 hasConcept C2777221637 @default.
- W4200604834 hasConcept C2778641530 @default.
- W4200604834 hasConcept C2779234561 @default.
- W4200604834 hasConcept C2779306644 @default.
- W4200604834 hasConcept C2779434492 @default.
- W4200604834 hasConcept C2780255968 @default.
- W4200604834 hasConcept C2780473172 @default.
- W4200604834 hasConcept C46973012 @default.
- W4200604834 hasConcept C523546767 @default.
- W4200604834 hasConcept C54355233 @default.
- W4200604834 hasConcept C555293320 @default.
- W4200604834 hasConcept C71924100 @default.
- W4200604834 hasConcept C86803240 @default.
- W4200604834 hasConceptScore W4200604834C126322002 @default.
- W4200604834 hasConceptScore W4200604834C134018914 @default.
- W4200604834 hasConceptScore W4200604834C142724271 @default.
- W4200604834 hasConceptScore W4200604834C168563851 @default.
- W4200604834 hasConceptScore W4200604834C204787440 @default.
- W4200604834 hasConceptScore W4200604834C27081682 @default.
- W4200604834 hasConceptScore W4200604834C2777221637 @default.
- W4200604834 hasConceptScore W4200604834C2778641530 @default.
- W4200604834 hasConceptScore W4200604834C2779234561 @default.
- W4200604834 hasConceptScore W4200604834C2779306644 @default.
- W4200604834 hasConceptScore W4200604834C2779434492 @default.
- W4200604834 hasConceptScore W4200604834C2780255968 @default.
- W4200604834 hasConceptScore W4200604834C2780473172 @default.
- W4200604834 hasConceptScore W4200604834C46973012 @default.
- W4200604834 hasConceptScore W4200604834C523546767 @default.
- W4200604834 hasConceptScore W4200604834C54355233 @default.
- W4200604834 hasConceptScore W4200604834C555293320 @default.
- W4200604834 hasConceptScore W4200604834C71924100 @default.
- W4200604834 hasConceptScore W4200604834C86803240 @default.
- W4200604834 hasIssue "1" @default.
- W4200604834 hasLocation W42006048341 @default.
- W4200604834 hasOpenAccess W4200604834 @default.
- W4200604834 hasPrimaryLocation W42006048341 @default.
- W4200604834 hasRelatedWork W2005944900 @default.
- W4200604834 hasRelatedWork W2063632543 @default.
- W4200604834 hasRelatedWork W2282509849 @default.
- W4200604834 hasRelatedWork W2301276283 @default.
- W4200604834 hasRelatedWork W2339080574 @default.
- W4200604834 hasRelatedWork W2488321571 @default.
- W4200604834 hasRelatedWork W2596735526 @default.
- W4200604834 hasRelatedWork W3093212774 @default.
- W4200604834 hasRelatedWork W2185136710 @default.
- W4200604834 hasRelatedWork W2597294153 @default.
- W4200604834 hasVolume "226" @default.
- W4200604834 isParatext "false" @default.
- W4200604834 isRetracted "false" @default.
- W4200604834 workType "article" @default.