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- W4200604837 abstract "Studies have showed that advanced maternal age (AMA) is associated with higher rates of preterm birth. Our study aimed to determine how the relationship between AMA and preterm birth has changed over time, and if there is variation by maternal race and ethnicity. This was a retrospective cohort study of singleton, non-anomalous deliveries with a gestational age ≥20 weeks and maternal age ≥35 in the United States from 2014-2018. We performed multivariable logistic regression analysis followed by calculation of adjusted predicted probabilities to estimate the fraction of deliveries resulting in preterm birth. STATA 17 was used for all analyses. Data was further stratified by maternal race/ethnicity, including non-Hispanic white, non-Hispanic Black, non-Hispanic American Indian/Alaskan Native (AI/AN) non-Hispanic Asian or Native Hawaiian or Pacific Islander (NHPI), non-Hispanic multiracial and Hispanic. Confounders assessed included age, parity, BMI, cigarette use, gestational diabetes mellitus, gestational hypertension, preeclampsia, eclampsia, educational attainment, and insurance type. There were 3,095,280 births included in this study. Black women, followed by Non-Hispanic AI/AN women, consistently had the highest probability of preterm birth from 2014-2018. Non-Hispanic White women consistently had the lowest probability. The predicted probabilities of preterm birth in all groups were higher in 2018 than 2014, apart from Black women. However, nearly all groups saw a progressive increase in preterm birth from 2014-2017, with a slight decrease from 2017-2018. The largest increase in preterm birth was in non-Hispanic AI/AN women from 2014-2017 with an increase from 9.9% to 11.8%, along with a subsequent decline to 10.6% in 2018. While trends were varied, most racial groups in the AMA population experienced an increase in preterm birth over much of our study period. There were significant disparities in preterm birth rates when considering maternal race and ethnicity, with Black and non-Hispanic AI/AN women most disproportionately affected." @default.
- W4200604837 created "2021-12-31" @default.
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- W4200604837 date "2022-01-01" @default.
- W4200604837 modified "2023-09-28" @default.
- W4200604837 title "Preterm Birth Trends by Race and Ethnicity Among Women with Advanced Maternal Age, 2014-2018" @default.
- W4200604837 doi "https://doi.org/10.1016/j.ajog.2021.11.901" @default.
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