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- W4200607501 endingPage "145" @default.
- W4200607501 startingPage "117" @default.
- W4200607501 abstract "Reactive oxygen species (ROS) transform cell responses through miscellaneous processes. These act as signalling molecules when present in low concentrations or damage cell machinery when present in high levels. ROS-mediated mitochondrial damage leads to lesser oxidative phosphorylation and enhanced cell death. Aberrant cell death and redox signalling are implicated in numerous pathological conditions such as cardiac, neurodegenerative, and metabolic diseases. Cells have adopted an auto-degradation process as a cytoprotective strategy by inhibition of aberrant cell death and oxidation stress along with activation of autophagy. Autophagy, a pervasive degradation or turnover homeostatic mechanism of cell organelles and components, involves differentiation and ageing. Any dysfunction of autophagy can lead to anomalous mitochondrial function and ROS. Redox signalling cascade is related to the etiology of ageing, and the cellular machinery that regulates redox, autophagy and ageing has been elucidated. Redox signalling orchestrates autophagy and ageing processes leading to altered transduction of redox homeostasis. This chapter discusses ageing process, generation of ROS, redox signalling, autophagy types and mechanisms, the interplay between redox signalling, autophagy and ageing." @default.
- W4200607501 created "2021-12-31" @default.
- W4200607501 creator A5037780425 @default.
- W4200607501 creator A5066701625 @default.
- W4200607501 creator A5077863015 @default.
- W4200607501 date "2021-12-03" @default.
- W4200607501 modified "2023-10-17" @default.
- W4200607501 title "Redox Signalling, Autophagy and Ageing" @default.
- W4200607501 cites W139355624 @default.
- W4200607501 cites W1535283655 @default.
- W4200607501 cites W1576137866 @default.
- W4200607501 cites W1800189887 @default.
- W4200607501 cites W1947637767 @default.
- W4200607501 cites W1965205152 @default.
- W4200607501 cites W1965470471 @default.
- W4200607501 cites W1967809393 @default.
- W4200607501 cites W1969476369 @default.
- W4200607501 cites W1973523024 @default.
- W4200607501 cites W1976950210 @default.
- W4200607501 cites W1994133951 @default.
- W4200607501 cites W1999713485 @default.
- W4200607501 cites W2009899766 @default.
- W4200607501 cites W2014320780 @default.
- W4200607501 cites W2016826534 @default.
- W4200607501 cites W2018885305 @default.
- W4200607501 cites W2019029563 @default.
- W4200607501 cites W2019486401 @default.
- W4200607501 cites W2021460489 @default.
- W4200607501 cites W2021632384 @default.
- W4200607501 cites W2023370693 @default.
- W4200607501 cites W2024782183 @default.
- W4200607501 cites W2036451354 @default.
- W4200607501 cites W2051429808 @default.
- W4200607501 cites W2066727453 @default.
- W4200607501 cites W2071419221 @default.
- W4200607501 cites W2072130124 @default.
- W4200607501 cites W2073841074 @default.
- W4200607501 cites W2085248094 @default.
- W4200607501 cites W2088988690 @default.
- W4200607501 cites W2089230333 @default.
- W4200607501 cites W2099928106 @default.
- W4200607501 cites W2102472842 @default.
- W4200607501 cites W2111757377 @default.
- W4200607501 cites W2115708356 @default.
- W4200607501 cites W2115788076 @default.
- W4200607501 cites W2117695104 @default.
- W4200607501 cites W2119159602 @default.
- W4200607501 cites W2124165909 @default.
- W4200607501 cites W2127179880 @default.
- W4200607501 cites W2130682212 @default.
- W4200607501 cites W2132826785 @default.
- W4200607501 cites W2133770419 @default.
- W4200607501 cites W2135704086 @default.
- W4200607501 cites W2139425230 @default.
- W4200607501 cites W2140664473 @default.
- W4200607501 cites W2143542604 @default.
- W4200607501 cites W2149236492 @default.
- W4200607501 cites W2154993563 @default.
- W4200607501 cites W2162418171 @default.
- W4200607501 cites W2170597525 @default.
- W4200607501 cites W2189790494 @default.
- W4200607501 cites W2277468569 @default.
- W4200607501 cites W2321548671 @default.
- W4200607501 cites W2325288941 @default.
- W4200607501 cites W2336416528 @default.
- W4200607501 cites W2350256796 @default.
- W4200607501 cites W2395947857 @default.
- W4200607501 cites W2417395786 @default.
- W4200607501 cites W2519786994 @default.
- W4200607501 cites W2521662433 @default.
- W4200607501 cites W2549447033 @default.
- W4200607501 cites W2564945524 @default.
- W4200607501 cites W2626543431 @default.
- W4200607501 cites W2740737691 @default.
- W4200607501 cites W2744534460 @default.
- W4200607501 cites W2767505663 @default.
- W4200607501 cites W2773006875 @default.
- W4200607501 cites W2776180915 @default.
- W4200607501 cites W2782358406 @default.
- W4200607501 cites W2783356125 @default.
- W4200607501 cites W2795223464 @default.
- W4200607501 cites W2795906582 @default.
- W4200607501 cites W2799986334 @default.
- W4200607501 cites W2800471357 @default.
- W4200607501 cites W2808169626 @default.
- W4200607501 cites W2810959600 @default.
- W4200607501 cites W2883813444 @default.
- W4200607501 cites W2886519525 @default.
- W4200607501 cites W2889101189 @default.
- W4200607501 cites W2892775161 @default.
- W4200607501 cites W2898520486 @default.
- W4200607501 cites W2900458090 @default.
- W4200607501 cites W2909362029 @default.
- W4200607501 cites W2909598539 @default.
- W4200607501 cites W2912186386 @default.
- W4200607501 cites W2941868496 @default.
- W4200607501 cites W2947610223 @default.
- W4200607501 cites W2949451258 @default.