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- W4200609672 abstract "To the Editor: In plaque psoriasis clinical trials, ≥75% reduction in the psoriasis area and severity index (PASI75) has traditionally been the benchmark for treatment efficacy. 1 Manalo I.F. Gilbert K.E. Wu J.J. Time to raise the bar to psoriasis area severity Index 90 and 100. J Drugs Dermatol. 2015; 14: 1086-1088 PubMed Google Scholar With the advent of newer biologics, PASI90 or PASI100 are becoming the new standard. 1 Manalo I.F. Gilbert K.E. Wu J.J. Time to raise the bar to psoriasis area severity Index 90 and 100. J Drugs Dermatol. 2015; 14: 1086-1088 PubMed Google Scholar Studies have shown that higher skin clearance is associated with better short-term patient-reported outcomes (PROs), such as symptom control and health-related quality of life (HRQL). 2 Feldman S.R. Bushnell D.M. Klekotka P.A. et al. Differences in psoriasis signs and symptom severity between patients with clear and almost clear skin in clinical practice. J Dermatolog Treat. 2016; 27: 224-227 Crossref PubMed Scopus (23) Google Scholar This study quantified the long-term impact on patient quality of life of achieving and maintaining complete-clearance (PASI100) and near-clearance (PASI90-99) compared to moderate-clearance (PASI75-89)." @default.
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- W4200609672 date "2023-01-01" @default.
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- W4200609672 title "The impact of achieving and maintaining near-complete or complete skin clearance on patient quality of life in moderate-to-severe psoriasis" @default.
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- W4200609672 doi "https://doi.org/10.1016/j.jaad.2021.12.032" @default.
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