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- W4200616204 abstract "Invasive fungal disease (IFD) due to moulds other than Aspergillus is a significant cause of mortality in patients with malignancies or post haemopoietic stem cell transplantation. The current guidelines focus on the diagnosis and management of the common non-Aspergillus moulds (NAM), such as Mucorales, Scedosporium species (spp.), Lomentospora prolificans and Fusarium spp. Rare but emerging NAM including Paecilomyces variotii, Purpureocillium lilacinum and Scopulariopsis spp. are also reviewed. Culture and histological examination of tissue biopsy specimens remain the mainstay of diagnosis, but molecular methods are increasingly being used. As NAM frequently disseminate, blood cultures and skin examination with biopsy of any suspicious lesions are critically important. Treatment requires a multidisciplinary approach with surgical debridement as a central component. Other management strategies include control of the underlying disease/predisposing factors, augmentation of the host response and the reduction of immunosuppression. Carefully selected antifungal therapy, guided by susceptibility testing, is critical to cure. We also outline novel antifungal agents still in clinical trial which offer substantial potential for improved outcomes in the future. Paediatric recommendations follow those of adults. Ongoing epidemiological research, improvement in diagnostics and the development of new antifungal agents will continue to improve the poor outcomes that have been traditionally associated with IFD due to NAM." @default.
- W4200616204 created "2021-12-31" @default.
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- W4200616204 date "2021-11-01" @default.
- W4200616204 modified "2023-10-18" @default.
- W4200616204 title "Consensus guidelines for the diagnosis and management of invasive fungal disease due to moulds other than <i>Aspergillus</i> in the haematology/oncology setting, 2021" @default.
- W4200616204 cites W1018112193 @default.
- W4200616204 cites W1486431645 @default.
- W4200616204 cites W1497721494 @default.
- W4200616204 cites W1528565239 @default.
- W4200616204 cites W1572196817 @default.
- W4200616204 cites W1598138377 @default.
- W4200616204 cites W1609495085 @default.
- W4200616204 cites W1654280973 @default.
- W4200616204 cites W1764330930 @default.
- W4200616204 cites W1772787872 @default.
- W4200616204 cites W1822623834 @default.
- W4200616204 cites W1873116759 @default.
- W4200616204 cites W1891119332 @default.
- W4200616204 cites W1908365728 @default.
- W4200616204 cites W1911492379 @default.
- W4200616204 cites W1914531459 @default.
- W4200616204 cites W1916258284 @default.
- W4200616204 cites W1916887957 @default.
- W4200616204 cites W1930296878 @default.
- W4200616204 cites W1932312459 @default.
- W4200616204 cites W1965997953 @default.
- W4200616204 cites W1966006459 @default.
- W4200616204 cites W1967749841 @default.
- W4200616204 cites W1969617415 @default.
- W4200616204 cites W1970096756 @default.
- W4200616204 cites W1973377550 @default.
- W4200616204 cites W1974241692 @default.
- W4200616204 cites W1976252594 @default.
- W4200616204 cites W1979627152 @default.
- W4200616204 cites W1981002518 @default.
- W4200616204 cites W1982325260 @default.
- W4200616204 cites W1982887395 @default.
- W4200616204 cites W1985810910 @default.
- W4200616204 cites W1990364433 @default.
- W4200616204 cites W1990371288 @default.
- W4200616204 cites W1990769336 @default.
- W4200616204 cites W1995763500 @default.
- W4200616204 cites W1997724791 @default.
- W4200616204 cites W2000165487 @default.
- W4200616204 cites W2005576438 @default.
- W4200616204 cites W2007962362 @default.
- W4200616204 cites W2011590188 @default.
- W4200616204 cites W2012628495 @default.
- W4200616204 cites W2013752016 @default.
- W4200616204 cites W2014616328 @default.
- W4200616204 cites W2014668109 @default.
- W4200616204 cites W2015036133 @default.
- W4200616204 cites W2017334109 @default.
- W4200616204 cites W2018193678 @default.
- W4200616204 cites W2034745870 @default.
- W4200616204 cites W2035054256 @default.
- W4200616204 cites W2035457590 @default.
- W4200616204 cites W2038062060 @default.
- W4200616204 cites W2038717385 @default.
- W4200616204 cites W2039443304 @default.
- W4200616204 cites W2042823694 @default.
- W4200616204 cites W2043482717 @default.
- W4200616204 cites W2046235332 @default.
- W4200616204 cites W2051949757 @default.
- W4200616204 cites W2052408066 @default.
- W4200616204 cites W2052584839 @default.
- W4200616204 cites W2053755183 @default.
- W4200616204 cites W2054211811 @default.
- W4200616204 cites W2058075520 @default.
- W4200616204 cites W2058571383 @default.
- W4200616204 cites W2059625789 @default.
- W4200616204 cites W2064332634 @default.
- W4200616204 cites W2068695218 @default.
- W4200616204 cites W2072143750 @default.
- W4200616204 cites W2073702534 @default.
- W4200616204 cites W2075767753 @default.
- W4200616204 cites W2077919952 @default.
- W4200616204 cites W2078268056 @default.
- W4200616204 cites W2079232635 @default.
- W4200616204 cites W2087548480 @default.
- W4200616204 cites W2089570261 @default.
- W4200616204 cites W2092827832 @default.