Matches in SemOpenAlex for { <https://semopenalex.org/work/W4200623384> ?p ?o ?g. }
Showing items 1 to 75 of
75
with 100 items per page.
- W4200623384 abstract "Abstract Bacteria of the genera Xenorhabdus and Photorhabdus are symbionts of entomopathogenic nematodes. Despite their close phylogenetic relationship, they show differences in their pathogenicity and virulence mechanisms in target insects. These differences can be explored by the analysis of the pangenome, as it provides a framework for characterizing and defining the gene repertoire. Here, we report the genome of strain SC 0516. In addition, we performed the first pangenome analysis of 91 strains of Xenorhabdus and Photorhabdus , obtaining a total of 23,603 gene clusters and a core genome of 348 genes. Phylogenetic analysis performed with the core genome showed that our strain belonged to the X. nematophila group. Biological tests showed that whole cells of X. nematophila SC 0516 were more virulent than those of P. luminescens HIM3 when both were injected into Galleria mellonella larvae. In addition, we cloned and expressed the GroEL proteins of both bacteria, as this protein has been previously indicated to show insecticidal activity in the genus Xenorhabdus. Cpn60-Xn was found to be the most toxic at all concentrations tested, with an LC 50 value of 102.34 ng/larva. Sequence analysis suggested that the Cpn60-Xn toxin was homologous to Cpn60-Pl; however, Cpn60-Xn contained thirty-five differentially substituted amino acid residues that could be responsible for its insecticidal activity." @default.
- W4200623384 created "2021-12-31" @default.
- W4200623384 creator A5006042536 @default.
- W4200623384 creator A5044367069 @default.
- W4200623384 creator A5056355090 @default.
- W4200623384 creator A5057272107 @default.
- W4200623384 creator A5070868500 @default.
- W4200623384 creator A5091612529 @default.
- W4200623384 date "2021-11-15" @default.
- W4200623384 modified "2023-10-18" @default.
- W4200623384 title "Comparative Genomics and Pathogenicity Analysis of Two Bacterial Symbionts of Entomopathogenic Nematodes: The Role of The GroEL Protein in Virulence" @default.
- W4200623384 doi "https://doi.org/10.21203/rs.3.rs-1032559/v1" @default.
- W4200623384 hasPublicationYear "2021" @default.
- W4200623384 type Work @default.
- W4200623384 citedByCount "0" @default.
- W4200623384 crossrefType "posted-content" @default.
- W4200623384 hasAuthorship W4200623384A5006042536 @default.
- W4200623384 hasAuthorship W4200623384A5044367069 @default.
- W4200623384 hasAuthorship W4200623384A5056355090 @default.
- W4200623384 hasAuthorship W4200623384A5057272107 @default.
- W4200623384 hasAuthorship W4200623384A5070868500 @default.
- W4200623384 hasAuthorship W4200623384A5091612529 @default.
- W4200623384 hasBestOaLocation W42006233841 @default.
- W4200623384 hasConcept C104317684 @default.
- W4200623384 hasConcept C105176652 @default.
- W4200623384 hasConcept C105702510 @default.
- W4200623384 hasConcept C141231307 @default.
- W4200623384 hasConcept C189206191 @default.
- W4200623384 hasConcept C193252679 @default.
- W4200623384 hasConcept C24432333 @default.
- W4200623384 hasConcept C2776074613 @default.
- W4200623384 hasConcept C2776213388 @default.
- W4200623384 hasConcept C2778022156 @default.
- W4200623384 hasConcept C2778758119 @default.
- W4200623384 hasConcept C2779032433 @default.
- W4200623384 hasConcept C54355233 @default.
- W4200623384 hasConcept C547475151 @default.
- W4200623384 hasConcept C60987743 @default.
- W4200623384 hasConcept C86803240 @default.
- W4200623384 hasConcept C87190427 @default.
- W4200623384 hasConcept C89423630 @default.
- W4200623384 hasConceptScore W4200623384C104317684 @default.
- W4200623384 hasConceptScore W4200623384C105176652 @default.
- W4200623384 hasConceptScore W4200623384C105702510 @default.
- W4200623384 hasConceptScore W4200623384C141231307 @default.
- W4200623384 hasConceptScore W4200623384C189206191 @default.
- W4200623384 hasConceptScore W4200623384C193252679 @default.
- W4200623384 hasConceptScore W4200623384C24432333 @default.
- W4200623384 hasConceptScore W4200623384C2776074613 @default.
- W4200623384 hasConceptScore W4200623384C2776213388 @default.
- W4200623384 hasConceptScore W4200623384C2778022156 @default.
- W4200623384 hasConceptScore W4200623384C2778758119 @default.
- W4200623384 hasConceptScore W4200623384C2779032433 @default.
- W4200623384 hasConceptScore W4200623384C54355233 @default.
- W4200623384 hasConceptScore W4200623384C547475151 @default.
- W4200623384 hasConceptScore W4200623384C60987743 @default.
- W4200623384 hasConceptScore W4200623384C86803240 @default.
- W4200623384 hasConceptScore W4200623384C87190427 @default.
- W4200623384 hasConceptScore W4200623384C89423630 @default.
- W4200623384 hasLocation W42006233841 @default.
- W4200623384 hasOpenAccess W4200623384 @default.
- W4200623384 hasPrimaryLocation W42006233841 @default.
- W4200623384 hasRelatedWork W2169255384 @default.
- W4200623384 hasRelatedWork W2295333121 @default.
- W4200623384 hasRelatedWork W2936463940 @default.
- W4200623384 hasRelatedWork W3037260512 @default.
- W4200623384 hasRelatedWork W3106911797 @default.
- W4200623384 hasRelatedWork W3123266606 @default.
- W4200623384 hasRelatedWork W4200623384 @default.
- W4200623384 hasRelatedWork W4225413415 @default.
- W4200623384 hasRelatedWork W4238324598 @default.
- W4200623384 hasRelatedWork W4243387438 @default.
- W4200623384 isParatext "false" @default.
- W4200623384 isRetracted "false" @default.
- W4200623384 workType "article" @default.