FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4205120225> ?p ?o ?g. }

• W4205120225 endingPage "151952" @default.
• W4205120225 startingPage "151952" @default.
• W4205120225 abstract "There is growing evidence from case reports that methotrexate (MTX) therapy may impair bone metabolism in individual patients leading to low bone mass, atraumatic stress fractures and immobilizing bone pain - referred to as 'MTX osteopathy'. However, the clinical features, risk factors and treatment options of this condition are still elusive.A systematic review was conducted according to PRISMA guidelines. Two databases (MEDLINE, Embase) were searched for published cases of MTX osteopathy in patients with rheumatic musculoskeletal diseases (RMD). Data from the included publications were extracted and descriptive statistical analysis was performed.We report data from 32 studies describing 80 adult RMD patients with stress fractures in MTX osteopathy. Most cases were found in elderly women with longstanding RMD, especially rheumatoid arthritis (72.5%). MTX osteopathy commonly presented as stress fracture of the distal tibia (51.3%), calcaneus (35.0%) and proximal tibia (27.5%), mimicking arthritis in some cases. Although a majority of the patients met the densitometric criteria for osteoporosis (58.1%), typical osteoporotic fractures (e.g., vertebral fractures) were rarely seen. Patients frequently suffered from bilateral (55.0%), multiple (71.3%) and recurrent fractures (25.0%). Fractures mainly occurred at low to moderate doses of MTX therapy (45.0%). It should be noted that half (48.8%) of the patients did not receive systemic steroid therapy for at least 3 years.Low-dose MTX therapy in RMD may result in atraumatic stress fractures of the lower extremity that can mimic arthritis. MTX osteopathy is characterized by a pathognomonic type of stress fractures with band- or meander-shaped appearance along the growth plate." @default.
• W4205120225 created "2022-01-25" @default.
• W4205120225 creator A5012696747 @default.
• W4205120225 creator A5047316251 @default.
• W4205120225 creator A5077500277 @default.
• W4205120225 creator A5079425977 @default.
• W4205120225 creator A5090589798 @default.
• W4205120225 date "2022-02-01" @default.
• W4205120225 modified "2023-09-26" @default.
• W4205120225 title "Clinical features of methotrexate osteopathy in rheumatic musculoskeletal disease: A systematic review" @default.
• W4205120225 cites W1963970520 @default.
• W4205120225 cites W1965442934 @default.
• W4205120225 cites W1973809848 @default.
• W4205120225 cites W1981352038 @default.
• W4205120225 cites W1982963755 @default.
• W4205120225 cites W1983591818 @default.
• W4205120225 cites W1988473352 @default.
• W4205120225 cites W2026058273 @default.
• W4205120225 cites W2027882144 @default.
• W4205120225 cites W2042368423 @default.
• W4205120225 cites W2053239895 @default.
• W4205120225 cites W2060194114 @default.
• W4205120225 cites W2065384666 @default.
• W4205120225 cites W2074889809 @default.
• W4205120225 cites W2090003352 @default.
• W4205120225 cites W2099148637 @default.
• W4205120225 cites W2119972092 @default.
• W4205120225 cites W2124060758 @default.
• W4205120225 cites W2130673505 @default.
• W4205120225 cites W2167510567 @default.
• W4205120225 cites W2323447201 @default.
• W4205120225 cites W2324844967 @default.
• W4205120225 cites W2343338963 @default.
• W4205120225 cites W2417261411 @default.
• W4205120225 cites W2560438049 @default.
• W4205120225 cites W2568632226 @default.
• W4205120225 cites W2623599370 @default.
• W4205120225 cites W2734878289 @default.
• W4205120225 cites W2811264888 @default.
• W4205120225 cites W2887981037 @default.
• W4205120225 cites W2930396228 @default.
• W4205120225 cites W3093011296 @default.
• W4205120225 cites W3097084299 @default.
• W4205120225 cites W3158847463 @default.
• W4205120225 cites W4231972505 @default.
• W4205120225 cites W4233534774 @default.
• W4205120225 cites W4240851330 @default.
• W4205120225 cites W4294215472 @default.
• W4205120225 cites W941899121 @default.
• W4205120225 doi "https://doi.org/10.1016/j.semarthrit.2022.151952" @default.
• W4205120225 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35038641" @default.
• W4205120225 hasPublicationYear "2022" @default.
• W4205120225 type Work @default.
• W4205120225 citedByCount "5" @default.
• W4205120225 countsByYear W42051202252022 @default.
• W4205120225 countsByYear W42051202252023 @default.
• W4205120225 crossrefType "journal-article" @default.
• W4205120225 hasAuthorship W4205120225A5012696747 @default.
• W4205120225 hasAuthorship W4205120225A5047316251 @default.
• W4205120225 hasAuthorship W4205120225A5077500277 @default.
• W4205120225 hasAuthorship W4205120225A5079425977 @default.
• W4205120225 hasAuthorship W4205120225A5090589798 @default.
• W4205120225 hasConcept C126322002 @default.
• W4205120225 hasConcept C141071460 @default.
• W4205120225 hasConcept C142724271 @default.
• W4205120225 hasConcept C204787440 @default.
• W4205120225 hasConcept C2776407475 @default.
• W4205120225 hasConcept C2776541429 @default.
• W4205120225 hasConcept C2776737378 @default.
• W4205120225 hasConcept C2776889875 @default.
• W4205120225 hasConcept C2777236700 @default.
• W4205120225 hasConcept C2777575956 @default.
• W4205120225 hasConcept C2778063842 @default.
• W4205120225 hasConcept C2779134260 @default.
• W4205120225 hasConcept C71924100 @default.
• W4205120225 hasConceptScore W4205120225C126322002 @default.
• W4205120225 hasConceptScore W4205120225C141071460 @default.
• W4205120225 hasConceptScore W4205120225C142724271 @default.
• W4205120225 hasConceptScore W4205120225C204787440 @default.
• W4205120225 hasConceptScore W4205120225C2776407475 @default.
• W4205120225 hasConceptScore W4205120225C2776541429 @default.
• W4205120225 hasConceptScore W4205120225C2776737378 @default.
• W4205120225 hasConceptScore W4205120225C2776889875 @default.
• W4205120225 hasConceptScore W4205120225C2777236700 @default.
• W4205120225 hasConceptScore W4205120225C2777575956 @default.
• W4205120225 hasConceptScore W4205120225C2778063842 @default.
• W4205120225 hasConceptScore W4205120225C2779134260 @default.
• W4205120225 hasConceptScore W4205120225C71924100 @default.
• W4205120225 hasLocation W42051202251 @default.
• W4205120225 hasLocation W42051202252 @default.
• W4205120225 hasOpenAccess W4205120225 @default.
• W4205120225 hasPrimaryLocation W42051202251 @default.
• W4205120225 hasRelatedWork W1483675033 @default.
• W4205120225 hasRelatedWork W1993495194 @default.
• W4205120225 hasRelatedWork W2024109006 @default.
• W4205120225 hasRelatedWork W2088535880 @default.
• W4205120225 hasRelatedWork W2150501640 @default.
• W4205120225 hasRelatedWork W2367328649 @default.

• next