FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4205120959> ?p ?o ?g. }

• W4205120959 endingPage "40" @default.
• W4205120959 startingPage "31" @default.
• W4205120959 abstract "Epstein-Barr virus (EBV) is an etiologic agent of infectious mononucleosis and several malignancies. Here, we found that reactivation of EBV resulted in increased programmed cell death-ligand 1 (PD-L1) expression in a cell type-dependent manner. Lytic induction in EBV-positive Akata, AGS, MutuI, and Jijoye cell lines increased PD-L1 levels, but cells such as EBV-negative Akata, MutuIII, and P3HR1 did not have increased PD-L1. EBV in the P3HR1 cell line has a deletion in the EBNA2 gene, while EBV in its parental cell line, Jijoye, has the complete EBNA2 gene. PD-L1 expression by lytic induction was reduced when EBNA2 was knocked down. In addition, pharmacological inhibition indicated involvement of nuclear factor kappa B, mitogen-activated protein kinase, and AKT signaling. These results suggest that EBV likely evades immunity by inducing PD-L1 upon reactivation, through the increased expression of EBNA2 and activation of signaling pathways." @default.
• W4205120959 created "2022-01-25" @default.
• W4205120959 creator A5001424767 @default.
• W4205120959 creator A5001746851 @default.
• W4205120959 creator A5030609965 @default.
• W4205120959 creator A5031084724 @default.
• W4205120959 creator A5036353568 @default.
• W4205120959 creator A5069937286 @default.
• W4205120959 creator A5079132507 @default.
• W4205120959 date "2022-03-01" @default.
• W4205120959 modified "2023-10-13" @default.
• W4205120959 title "PD-L1 upregulation by lytic induction of Epstein-Barr Virus" @default.
• W4205120959 cites W1580014811 @default.
• W4205120959 cites W1605908963 @default.
• W4205120959 cites W1937139132 @default.
• W4205120959 cites W1979298871 @default.
• W4205120959 cites W2015616819 @default.
• W4205120959 cites W2026608413 @default.
• W4205120959 cites W2035638697 @default.
• W4205120959 cites W2059309083 @default.
• W4205120959 cites W2070503170 @default.
• W4205120959 cites W2104350866 @default.
• W4205120959 cites W2108233169 @default.
• W4205120959 cites W2125514026 @default.
• W4205120959 cites W2126547130 @default.
• W4205120959 cites W2135644627 @default.
• W4205120959 cites W2152833548 @default.
• W4205120959 cites W2171741398 @default.
• W4205120959 cites W2320954544 @default.
• W4205120959 cites W2522939951 @default.
• W4205120959 cites W2529923789 @default.
• W4205120959 cites W2603029028 @default.
• W4205120959 cites W2802879296 @default.
• W4205120959 cites W2808538116 @default.
• W4205120959 cites W2811453807 @default.
• W4205120959 cites W2890683768 @default.
• W4205120959 cites W2894427135 @default.
• W4205120959 cites W2910154923 @default.
• W4205120959 cites W2911909558 @default.
• W4205120959 cites W2912282769 @default.
• W4205120959 cites W2924942422 @default.
• W4205120959 cites W2938157475 @default.
• W4205120959 cites W2963804040 @default.
• W4205120959 cites W2965553739 @default.
• W4205120959 cites W3032063229 @default.
• W4205120959 cites W3046818880 @default.
• W4205120959 cites W3093328654 @default.
• W4205120959 cites W3131347681 @default.
• W4205120959 cites W3136052775 @default.
• W4205120959 cites W3137931912 @default.
• W4205120959 cites W3146110990 @default.
• W4205120959 cites W3193206407 @default.
• W4205120959 cites W4248078658 @default.
• W4205120959 doi "https://doi.org/10.1016/j.virol.2022.01.006" @default.
• W4205120959 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35093708" @default.
• W4205120959 hasPublicationYear "2022" @default.
• W4205120959 type Work @default.
• W4205120959 citedByCount "4" @default.
• W4205120959 countsByYear W42051209592022 @default.
• W4205120959 countsByYear W42051209592023 @default.
• W4205120959 crossrefType "journal-article" @default.
• W4205120959 hasAuthorship W4205120959A5001424767 @default.
• W4205120959 hasAuthorship W4205120959A5001746851 @default.
• W4205120959 hasAuthorship W4205120959A5030609965 @default.
• W4205120959 hasAuthorship W4205120959A5031084724 @default.
• W4205120959 hasAuthorship W4205120959A5036353568 @default.
• W4205120959 hasAuthorship W4205120959A5069937286 @default.
• W4205120959 hasAuthorship W4205120959A5079132507 @default.
• W4205120959 hasBestOaLocation W42051209591 @default.
• W4205120959 hasConcept C104317684 @default.
• W4205120959 hasConcept C127561419 @default.
• W4205120959 hasConcept C150194340 @default.
• W4205120959 hasConcept C153911025 @default.
• W4205120959 hasConcept C159047783 @default.
• W4205120959 hasConcept C182615771 @default.
• W4205120959 hasConcept C203014093 @default.
• W4205120959 hasConcept C2522874641 @default.
• W4205120959 hasConcept C2781375147 @default.
• W4205120959 hasConcept C502942594 @default.
• W4205120959 hasConcept C54355233 @default.
• W4205120959 hasConcept C81885089 @default.
• W4205120959 hasConcept C86803240 @default.
• W4205120959 hasConcept C8891405 @default.
• W4205120959 hasConceptScore W4205120959C104317684 @default.
• W4205120959 hasConceptScore W4205120959C127561419 @default.
• W4205120959 hasConceptScore W4205120959C150194340 @default.
• W4205120959 hasConceptScore W4205120959C153911025 @default.
• W4205120959 hasConceptScore W4205120959C159047783 @default.
• W4205120959 hasConceptScore W4205120959C182615771 @default.
• W4205120959 hasConceptScore W4205120959C203014093 @default.
• W4205120959 hasConceptScore W4205120959C2522874641 @default.
• W4205120959 hasConceptScore W4205120959C2781375147 @default.
• W4205120959 hasConceptScore W4205120959C502942594 @default.
• W4205120959 hasConceptScore W4205120959C54355233 @default.
• W4205120959 hasConceptScore W4205120959C81885089 @default.
• W4205120959 hasConceptScore W4205120959C86803240 @default.
• W4205120959 hasConceptScore W4205120959C8891405 @default.
• W4205120959 hasFunder F4320309807 @default.

• next