Matches in SemOpenAlex for { <https://semopenalex.org/work/W4205124716> ?p ?o ?g. }
- W4205124716 endingPage "12" @default.
- W4205124716 startingPage "1" @default.
- W4205124716 abstract "Ophidism is a serious health problem worldwide and is included in the World Health Organization's (WHO's) list of Neglected Tropical Diseases. Although snakebite envenoming requires emergency treatment, currently the only treatment recommended by WHO is serotherapy, which has some disadvantages such as low access to the rural population, low effectiveness in neutralizing local effects, and high cost. In this context, new alternatives for the treatment of snakebites are required. The use of plant-derived compounds to inhibit the effects caused by snake venoms has been the object of a number of studies in recent years. This review aims to provide an up-to-date overview of the use of phenolic acids with therapeutic application against envenomation by snakes of different species. In this sense, structural analysis in silico and biological activities in vivo and in vitro were reported. The acids were subdivided into derivatives of benzoic and cinnamic acids, with derivatives of cinnamic acids being the most studied. Studies have revealed that these compounds are capable of inhibiting local and systemic effects induced by envenomation, and structural analyses indicate that the acids interact with important sites responsible for the action of toxins. Thus, it was reported that phenolic acids showed antiophidic potential, providing insights for future research to develop complementary drugs for the treatment of snakebites." @default.
- W4205124716 created "2022-01-25" @default.
- W4205124716 creator A5006466399 @default.
- W4205124716 creator A5010736475 @default.
- W4205124716 creator A5048661242 @default.
- W4205124716 creator A5056121017 @default.
- W4205124716 creator A5065271407 @default.
- W4205124716 date "2022-03-01" @default.
- W4205124716 modified "2023-09-23" @default.
- W4205124716 title "The potential of phenolic acids in therapy against snakebites: A review" @default.
- W4205124716 cites W1608517416 @default.
- W4205124716 cites W1963530995 @default.
- W4205124716 cites W1967868924 @default.
- W4205124716 cites W1968875577 @default.
- W4205124716 cites W1969310555 @default.
- W4205124716 cites W1970838759 @default.
- W4205124716 cites W1971286215 @default.
- W4205124716 cites W1980387413 @default.
- W4205124716 cites W1980742802 @default.
- W4205124716 cites W1981107361 @default.
- W4205124716 cites W1987355196 @default.
- W4205124716 cites W1992478044 @default.
- W4205124716 cites W1995009837 @default.
- W4205124716 cites W2003075532 @default.
- W4205124716 cites W2012977074 @default.
- W4205124716 cites W2022533321 @default.
- W4205124716 cites W2025395935 @default.
- W4205124716 cites W2025499590 @default.
- W4205124716 cites W2026433506 @default.
- W4205124716 cites W2032788111 @default.
- W4205124716 cites W2033998601 @default.
- W4205124716 cites W2044140319 @default.
- W4205124716 cites W2047924909 @default.
- W4205124716 cites W2048013243 @default.
- W4205124716 cites W2052071560 @default.
- W4205124716 cites W2052731599 @default.
- W4205124716 cites W2060029293 @default.
- W4205124716 cites W2065683944 @default.
- W4205124716 cites W2066291439 @default.
- W4205124716 cites W2080676339 @default.
- W4205124716 cites W2091841989 @default.
- W4205124716 cites W2111175831 @default.
- W4205124716 cites W2137399536 @default.
- W4205124716 cites W2139051050 @default.
- W4205124716 cites W2148950790 @default.
- W4205124716 cites W2177846076 @default.
- W4205124716 cites W2293935230 @default.
- W4205124716 cites W2402438326 @default.
- W4205124716 cites W2416985615 @default.
- W4205124716 cites W2524663738 @default.
- W4205124716 cites W2550810430 @default.
- W4205124716 cites W2563999700 @default.
- W4205124716 cites W2580110333 @default.
- W4205124716 cites W2592338368 @default.
- W4205124716 cites W2618153170 @default.
- W4205124716 cites W2754620869 @default.
- W4205124716 cites W2766773093 @default.
- W4205124716 cites W2767209834 @default.
- W4205124716 cites W2767571806 @default.
- W4205124716 cites W2770909295 @default.
- W4205124716 cites W2772819376 @default.
- W4205124716 cites W2778152698 @default.
- W4205124716 cites W2795534618 @default.
- W4205124716 cites W2804526021 @default.
- W4205124716 cites W2806655963 @default.
- W4205124716 cites W2807827223 @default.
- W4205124716 cites W2887382088 @default.
- W4205124716 cites W2894569405 @default.
- W4205124716 cites W2910792142 @default.
- W4205124716 cites W2914130441 @default.
- W4205124716 cites W2922659213 @default.
- W4205124716 cites W2942365014 @default.
- W4205124716 cites W2947519203 @default.
- W4205124716 cites W2947947743 @default.
- W4205124716 cites W2952519293 @default.
- W4205124716 cites W3002198559 @default.
- W4205124716 cites W3024307068 @default.
- W4205124716 cites W3026111389 @default.
- W4205124716 cites W3036119229 @default.
- W4205124716 cites W3038215079 @default.
- W4205124716 cites W3042542245 @default.
- W4205124716 cites W3043402975 @default.
- W4205124716 cites W3062649699 @default.
- W4205124716 cites W3071237478 @default.
- W4205124716 cites W30752666 @default.
- W4205124716 cites W3081085071 @default.
- W4205124716 cites W3106125810 @default.
- W4205124716 cites W3108206064 @default.
- W4205124716 cites W3109055265 @default.
- W4205124716 cites W3111805126 @default.
- W4205124716 cites W3112178926 @default.
- W4205124716 cites W3113037061 @default.
- W4205124716 cites W3115525823 @default.
- W4205124716 cites W3128128702 @default.
- W4205124716 cites W3142785676 @default.
- W4205124716 cites W3158076431 @default.
- W4205124716 cites W3174606556 @default.
- W4205124716 cites W3187022953 @default.