Matches in SemOpenAlex for { <https://semopenalex.org/work/W4205157957> ?p ?o ?g. }
- W4205157957 endingPage "1132" @default.
- W4205157957 startingPage "1107" @default.
- W4205157957 abstract "Triazine derivatives have attracted increasing attention due to their diverse applications in medicinal chemistry. They have been reported to be remarkably effective compounds regarding their bioactivities. Therefore, the synthesis and identification of new triazine-derived compounds are of interest for their therapeutic effects. Various approaches have been developed to synthesize triazine derivatives. In this review, a considerable number of studies on the synthesis of 1,2,4-triazine derivatives are investigated with 4-amino-3-thioxo-6-substituted-1,2,4-triazin-ones and 4-amino-3-hydrazino-6-substituted-1,2,4-triazin-5-ones as starting materials. Different types of chemical reactions have been applied to the efficient synthesis of 3-thioxo/hydrazino-6-substituted-1,2,4-triazin-5-ones, such as alkylation, acylation, aroylation, elimination, substitution, acidic/basic hydrolysis, oxidation, cyclocondensation, cycloaddition, phosphorylation, and complexation reactions. Interestingly, a set of compounds is identified to possess various biological activities, such as anticancer antibacterial, antifungal, acaricidal, and molluscicidal properties. Also, some 4-amino-3-thioxo-6-substituted-1,2,4-triazin-5-one derivatives are found to form metal complexes, be used as inhibitor probes for mild steel corrosion, prepare a selective sensor for the determination of gadolinium (III) ions in the soil and sediment samples, and demonstrate antibacterial activities. Finally, 4-amino-3-hydrazino-6-methyl-1,2,4-triazin-5-one was used as an ionophore to develop a chromium (III) ion-selective sensor beside the formation of silver complexes." @default.
- W4205157957 created "2022-01-26" @default.
- W4205157957 creator A5053953775 @default.
- W4205157957 creator A5062896607 @default.
- W4205157957 date "2022-01-12" @default.
- W4205157957 modified "2023-09-27" @default.
- W4205157957 title "Synthesis, Reactivity, and Applications of 4-Amino-3-Thioxo/Hydrazino-6-Substituted-1,2,4-Triazin-5-Ones and Their Derivatives: A Review" @default.
- W4205157957 cites W139907956 @default.
- W4205157957 cites W1580531622 @default.
- W4205157957 cites W1909346396 @default.
- W4205157957 cites W1965105862 @default.
- W4205157957 cites W1965281373 @default.
- W4205157957 cites W1971494220 @default.
- W4205157957 cites W1975130354 @default.
- W4205157957 cites W1976759198 @default.
- W4205157957 cites W1980983383 @default.
- W4205157957 cites W1986393586 @default.
- W4205157957 cites W1988726224 @default.
- W4205157957 cites W1988774048 @default.
- W4205157957 cites W1989664046 @default.
- W4205157957 cites W1994797791 @default.
- W4205157957 cites W1995459743 @default.
- W4205157957 cites W1996370639 @default.
- W4205157957 cites W2002279144 @default.
- W4205157957 cites W2005679184 @default.
- W4205157957 cites W2006315817 @default.
- W4205157957 cites W2010129935 @default.
- W4205157957 cites W2015017547 @default.
- W4205157957 cites W2019328423 @default.
- W4205157957 cites W2023102750 @default.
- W4205157957 cites W2023587197 @default.
- W4205157957 cites W2028307214 @default.
- W4205157957 cites W2029475615 @default.
- W4205157957 cites W2032450966 @default.
- W4205157957 cites W2033877761 @default.
- W4205157957 cites W2037633981 @default.
- W4205157957 cites W2042289785 @default.
- W4205157957 cites W2042843457 @default.
- W4205157957 cites W2043255842 @default.
- W4205157957 cites W2047716625 @default.
- W4205157957 cites W2051769390 @default.
- W4205157957 cites W2056107490 @default.
- W4205157957 cites W2057013934 @default.
- W4205157957 cites W2061547101 @default.
- W4205157957 cites W2063855572 @default.
- W4205157957 cites W2064115517 @default.
- W4205157957 cites W2074137796 @default.
- W4205157957 cites W2075687251 @default.
- W4205157957 cites W2077811490 @default.
- W4205157957 cites W2079067339 @default.
- W4205157957 cites W2079229949 @default.
- W4205157957 cites W2090277801 @default.
- W4205157957 cites W2090709008 @default.
- W4205157957 cites W2093712759 @default.
- W4205157957 cites W2104625973 @default.
- W4205157957 cites W2112920160 @default.
- W4205157957 cites W2119903332 @default.
- W4205157957 cites W2135060760 @default.
- W4205157957 cites W2143694165 @default.
- W4205157957 cites W2147836283 @default.
- W4205157957 cites W2156734615 @default.
- W4205157957 cites W2158303359 @default.
- W4205157957 cites W2166864403 @default.
- W4205157957 cites W2167720104 @default.
- W4205157957 cites W2171125432 @default.
- W4205157957 cites W2172782955 @default.
- W4205157957 cites W2172960271 @default.
- W4205157957 cites W2176884666 @default.
- W4205157957 cites W2278107564 @default.
- W4205157957 cites W2299247676 @default.
- W4205157957 cites W2313583825 @default.
- W4205157957 cites W2313777686 @default.
- W4205157957 cites W2322549392 @default.
- W4205157957 cites W2326989478 @default.
- W4205157957 cites W2340307318 @default.
- W4205157957 cites W2497223859 @default.
- W4205157957 cites W2531421132 @default.
- W4205157957 cites W2591727007 @default.
- W4205157957 cites W2598689239 @default.
- W4205157957 cites W2608380921 @default.
- W4205157957 cites W2742232675 @default.
- W4205157957 cites W2742654522 @default.
- W4205157957 cites W2744376947 @default.
- W4205157957 cites W2766184138 @default.
- W4205157957 cites W2771443936 @default.
- W4205157957 cites W2779371604 @default.
- W4205157957 cites W2791393163 @default.
- W4205157957 cites W2792226071 @default.
- W4205157957 cites W2800250011 @default.
- W4205157957 cites W2888435729 @default.
- W4205157957 cites W2892277437 @default.
- W4205157957 cites W2896849741 @default.
- W4205157957 cites W2896916516 @default.
- W4205157957 cites W2897459551 @default.
- W4205157957 cites W2899775443 @default.
- W4205157957 cites W2902556622 @default.
- W4205157957 cites W2903732938 @default.
- W4205157957 cites W2911861616 @default.