Matches in SemOpenAlex for { <https://semopenalex.org/work/W4205358133> ?p ?o ?g. }
- W4205358133 endingPage "132" @default.
- W4205358133 startingPage "132" @default.
- W4205358133 abstract "The purpose of this study was to investigate the effects of chemically protected sodium butyrate (CSB) on growth performance and the early development and function of small intestine in broilers as one potential substitute for antibiotics. A total of 192 one-day-old Arbor Acres male broilers were randomly assigned into three dietary treatment groups (eight replicates per treatment): the control (CON) diet; ANT diet, CON diet supplemented with the antibiotics (enramycin, 8 mg/kg and aureomycin, 100 mg/kg); CSB diet, CON diet supplemented with 1000 mg/kg CSB, respectively. The results showed that dietary CSB and antibiotics addition significantly improved the growth performance of broilers by increasing the body weight gain (BWG) and feed conversion ratio (FCR) during different stages (p < 0.05). On day 21, the supplement of CSB in diet improved the structure of small intestine (duodenum, jejunum, and ileum) in broilers by increasing the ratio of villus height to crypt depth (VH/CD) (p < 0.05) and enhanced the butyric acid (BA) (p < 0.05) and total short chain fatty acids (SCFA) concentrations of small intestine (jejunum and ileum) compared with the CON and ANT diets. Besides that, the superoxide dismutase (SOD), total antioxidant capacity (TAC) and TAC to malondialdehyde (TAC/MDA) ratio of the ileal and jejunal mucosa were significantly higher (p < 0.05) in the CSB and ANT than in the CON. In addition, the supplement of CSB in diet markedly significantly enhanced α-amylase, lipase, and trypsin activities of the ileum (p < 0.05) as compared to the ANT diet. 16S rRNA gene sequencing indicated that CSB markedly increased the microbiota diversity of ileum in broilers at 21 days of age as compared to CON and ANT (p < 0.05). Furthermore, we found that Firmicutes was the predominant phyla and Lactobacillus was the major genus in the ileum of broilers. Compared with the ANT diet, the supplement of CSB in diet increased the relative abundance of some genera microbiota (e.g., Candidatus_Arthromitus, Romboutsia) by decreasing the relative abundance of Lactobacillus. Moreover, Akkermansia in the CSB was the highest in comparison to that in the CON and ANT. In addition, Kitasatospora that belongs to the phylum Actinobacteriota was only found in ileum of broilers fed the ANT diet. In summary, the supplement of 1000 mg/kg CSB in the diet improved the growth performance by promoting early development and function of the small intestine, which is associated with the regulation of intestinal flora and reestablishment of micro-ecological balance in broilers. Thus, CSB has great potential value as one of effective substitutes for in-feed antibiotics in the broiler industry." @default.
- W4205358133 created "2022-01-26" @default.
- W4205358133 creator A5007978359 @default.
- W4205358133 creator A5011487190 @default.
- W4205358133 creator A5026965141 @default.
- W4205358133 creator A5034332113 @default.
- W4205358133 creator A5040367859 @default.
- W4205358133 creator A5050294038 @default.
- W4205358133 creator A5079795759 @default.
- W4205358133 date "2022-01-20" @default.
- W4205358133 modified "2023-10-05" @default.
- W4205358133 title "Chemically Protected Sodium Butyrate Improves Growth Performance and Early Development and Function of Small Intestine in Broilers as One Effective Substitute for Antibiotics" @default.
- W4205358133 cites W1956810582 @default.
- W4205358133 cites W1972799731 @default.
- W4205358133 cites W1975294542 @default.
- W4205358133 cites W1999571334 @default.
- W4205358133 cites W2004699378 @default.
- W4205358133 cites W2018080135 @default.
- W4205358133 cites W2027105854 @default.
- W4205358133 cites W2027271580 @default.
- W4205358133 cites W2027352386 @default.
- W4205358133 cites W2034168280 @default.
- W4205358133 cites W2055202343 @default.
- W4205358133 cites W2071687061 @default.
- W4205358133 cites W2076386438 @default.
- W4205358133 cites W2084164305 @default.
- W4205358133 cites W2086216523 @default.
- W4205358133 cites W2098209207 @default.
- W4205358133 cites W2109036589 @default.
- W4205358133 cites W2116224125 @default.
- W4205358133 cites W2142706243 @default.
- W4205358133 cites W2147790901 @default.
- W4205358133 cites W2265656215 @default.
- W4205358133 cites W2313426041 @default.
- W4205358133 cites W2315325285 @default.
- W4205358133 cites W2339991872 @default.
- W4205358133 cites W2408603146 @default.
- W4205358133 cites W2412082185 @default.
- W4205358133 cites W2527954043 @default.
- W4205358133 cites W2550084345 @default.
- W4205358133 cites W2570799132 @default.
- W4205358133 cites W2571212804 @default.
- W4205358133 cites W2573213362 @default.
- W4205358133 cites W2588469585 @default.
- W4205358133 cites W2619496069 @default.
- W4205358133 cites W2730479429 @default.
- W4205358133 cites W2736789929 @default.
- W4205358133 cites W2741691572 @default.
- W4205358133 cites W2754685212 @default.
- W4205358133 cites W2765274345 @default.
- W4205358133 cites W2791055437 @default.
- W4205358133 cites W2796527107 @default.
- W4205358133 cites W2803648188 @default.
- W4205358133 cites W2806782623 @default.
- W4205358133 cites W2883041645 @default.
- W4205358133 cites W2898139900 @default.
- W4205358133 cites W2902769857 @default.
- W4205358133 cites W2915788856 @default.
- W4205358133 cites W2924916996 @default.
- W4205358133 cites W2938282721 @default.
- W4205358133 cites W2941578712 @default.
- W4205358133 cites W2947129243 @default.
- W4205358133 cites W2948078074 @default.
- W4205358133 cites W2948269492 @default.
- W4205358133 cites W2957585395 @default.
- W4205358133 cites W2979006813 @default.
- W4205358133 cites W2994636178 @default.
- W4205358133 cites W3003722003 @default.
- W4205358133 cites W3009776666 @default.
- W4205358133 cites W3023140931 @default.
- W4205358133 cites W3041431516 @default.
- W4205358133 cites W3112981143 @default.
- W4205358133 cites W3150253863 @default.
- W4205358133 cites W3150666400 @default.
- W4205358133 cites W3152767914 @default.
- W4205358133 cites W3169858558 @default.
- W4205358133 cites W3184715238 @default.
- W4205358133 cites W4237404322 @default.
- W4205358133 cites W4237663336 @default.
- W4205358133 doi "https://doi.org/10.3390/antibiotics11020132" @default.
- W4205358133 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35203735" @default.
- W4205358133 hasPublicationYear "2022" @default.
- W4205358133 type Work @default.
- W4205358133 citedByCount "8" @default.
- W4205358133 countsByYear W42053581332022 @default.
- W4205358133 countsByYear W42053581332023 @default.
- W4205358133 crossrefType "journal-article" @default.
- W4205358133 hasAuthorship W4205358133A5007978359 @default.
- W4205358133 hasAuthorship W4205358133A5011487190 @default.
- W4205358133 hasAuthorship W4205358133A5026965141 @default.
- W4205358133 hasAuthorship W4205358133A5034332113 @default.
- W4205358133 hasAuthorship W4205358133A5040367859 @default.
- W4205358133 hasAuthorship W4205358133A5050294038 @default.
- W4205358133 hasAuthorship W4205358133A5079795759 @default.
- W4205358133 hasBestOaLocation W42053581331 @default.
- W4205358133 hasConcept C100544194 @default.
- W4205358133 hasConcept C104317684 @default.
- W4205358133 hasConcept C126322002 @default.