FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4205371923> ?p ?o ?g. }

• W4205371923 endingPage "011508" @default.
• W4205371923 startingPage "011508" @default.
• W4205371923 abstract "The field of radiation countermeasures is growing, however, currently there are no effective and non-toxic compounds which could be administered orally to the individuals post exposure to high doses of ionising radiation. The pigment melanin is ubiquitous through all kingdoms of life and provides selective advantage under radiation stress through its role as a chemical and physical shield, and its capacity to respond and react to exposures. Soluble allomelanin was administered to mice following whole-body exposure to lethal or sublethal doses of gamma radiation to determine its capacity to mitigate the effects of acute radiation syndrome, and its utility as a radiation countermeasure. Allomelanin has shown a trend to improve survival post an 8 Gy sublethal radiation exposure when administered up to 48 h post-irradiation. Furthermore, it improved median and overall survival to a 10 Gy lethal radiation exposure, specifically when administered at 24 h post-irradiation. Histological analysis on the jejunum region of the small intestine of this treatment group indicated that alterations of the mucosal and submucosal architecture, and disruption of the lymphatic system associated with lethal radiation exposure were mitigated when allomelanin was administered at 24 h post-irradiation. Based on this work soluble allomelanin derived from a fungal source could serve as an easily sourced, cost-effective, and viable countermeasure to accidental radiation exposure and merits further investigation." @default.
• W4205371923 created "2022-01-25" @default.
• W4205371923 creator A5028681383 @default.
• W4205371923 creator A5034610205 @default.
• W4205371923 creator A5036434465 @default.
• W4205371923 creator A5065251951 @default.
• W4205371923 creator A5079419201 @default.
• W4205371923 creator A5083228009 @default.
• W4205371923 creator A5088116243 @default.
• W4205371923 date "2022-01-17" @default.
• W4205371923 modified "2023-10-16" @default.
• W4205371923 title "Mitigating effects of sublethal and lethal whole-body gamma irradiation in a mouse model with soluble melanin" @default.
• W4205371923 cites W1497018435 @default.
• W4205371923 cites W1963544770 @default.
• W4205371923 cites W1967782781 @default.
• W4205371923 cites W1978859739 @default.
• W4205371923 cites W1985676268 @default.
• W4205371923 cites W2024719775 @default.
• W4205371923 cites W2030572777 @default.
• W4205371923 cites W2051833174 @default.
• W4205371923 cites W2058116796 @default.
• W4205371923 cites W2059699981 @default.
• W4205371923 cites W2070055629 @default.
• W4205371923 cites W2089624283 @default.
• W4205371923 cites W2091771822 @default.
• W4205371923 cites W2096411324 @default.
• W4205371923 cites W2113652002 @default.
• W4205371923 cites W2117410086 @default.
• W4205371923 cites W2117966833 @default.
• W4205371923 cites W2118636832 @default.
• W4205371923 cites W2130676718 @default.
• W4205371923 cites W2143046674 @default.
• W4205371923 cites W2145606492 @default.
• W4205371923 cites W2147296837 @default.
• W4205371923 cites W2149265347 @default.
• W4205371923 cites W2152944453 @default.
• W4205371923 cites W2155208388 @default.
• W4205371923 cites W2163274156 @default.
• W4205371923 cites W2205458319 @default.
• W4205371923 cites W2326176611 @default.
• W4205371923 cites W2567067044 @default.
• W4205371923 cites W2576450997 @default.
• W4205371923 cites W2752461632 @default.
• W4205371923 cites W2765625073 @default.
• W4205371923 cites W2895862161 @default.
• W4205371923 cites W2895956896 @default.
• W4205371923 cites W2901668014 @default.
• W4205371923 cites W2910153292 @default.
• W4205371923 cites W2911016058 @default.
• W4205371923 cites W2935194609 @default.
• W4205371923 cites W2937449096 @default.
• W4205371923 cites W2951686248 @default.
• W4205371923 cites W2983554556 @default.
• W4205371923 cites W2988241050 @default.
• W4205371923 cites W2992780110 @default.
• W4205371923 cites W3027658010 @default.
• W4205371923 cites W3084505478 @default.
• W4205371923 cites W3095661830 @default.
• W4205371923 cites W3103044812 @default.
• W4205371923 cites W3112247898 @default.
• W4205371923 cites W3126864184 @default.
• W4205371923 cites W3127040488 @default.
• W4205371923 cites W3164139996 @default.
• W4205371923 cites W4246970500 @default.
• W4205371923 doi "https://doi.org/10.1088/1361-6498/ac3dcf" @default.
• W4205371923 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35037901" @default.
• W4205371923 hasPublicationYear "2022" @default.
• W4205371923 type Work @default.
• W4205371923 citedByCount "4" @default.
• W4205371923 countsByYear W42053719232022 @default.
• W4205371923 countsByYear W42053719232023 @default.
• W4205371923 crossrefType "journal-article" @default.
• W4205371923 hasAuthorship W4205371923A5028681383 @default.
• W4205371923 hasAuthorship W4205371923A5034610205 @default.
• W4205371923 hasAuthorship W4205371923A5036434465 @default.
• W4205371923 hasAuthorship W4205371923A5065251951 @default.
• W4205371923 hasAuthorship W4205371923A5079419201 @default.
• W4205371923 hasAuthorship W4205371923A5083228009 @default.
• W4205371923 hasAuthorship W4205371923A5088116243 @default.
• W4205371923 hasConcept C109159458 @default.
• W4205371923 hasConcept C111337013 @default.
• W4205371923 hasConcept C121332964 @default.
• W4205371923 hasConcept C18231593 @default.
• W4205371923 hasConcept C185544564 @default.
• W4205371923 hasConcept C2777544843 @default.
• W4205371923 hasConcept C2779925993 @default.
• W4205371923 hasConcept C28328180 @default.
• W4205371923 hasConcept C2908890008 @default.
• W4205371923 hasConcept C2989005 @default.
• W4205371923 hasConcept C33070731 @default.
• W4205371923 hasConcept C42407357 @default.
• W4205371923 hasConcept C54355233 @default.
• W4205371923 hasConcept C71924100 @default.
• W4205371923 hasConcept C86803240 @default.
• W4205371923 hasConceptScore W4205371923C109159458 @default.
• W4205371923 hasConceptScore W4205371923C111337013 @default.
• W4205371923 hasConceptScore W4205371923C121332964 @default.
• W4205371923 hasConceptScore W4205371923C18231593 @default.

• next