Matches in SemOpenAlex for { <https://semopenalex.org/work/W4205383019> ?p ?o ?g. }
Showing items 1 to 63 of
63
with 100 items per page.
- W4205383019 endingPage "e2254" @default.
- W4205383019 startingPage "e2254" @default.
- W4205383019 abstract "Background: According to the increasing incidence of Alzheimer’s disease (AD), this study aimed to investigate the effect of dental pulp stem cells (DPSCs) transplantation on passive avoidance memory and neuroinflammation in trimethyltin (TMT)-induced AD rat model. Materials and Methods: In this experimental study, 18 male Wistar rats were randomly divided into three groups: the control that rats received 8 mg/kg TMT plus 0.5 ml phosphate buffered saline (PBS) and TMT+DPSCs (TMT + 1×106 cells/ml DPSC in 0.5 ml PBS) groups. Then, after one month, passive avoidance test was performed. Also measured the Nuclear Factor Kappa-β (NF-Kβ) serum level and the percentage of damaged neurons in the hippocampus were determined. Results: DPSCs transplantation showed significantly increased step-through latency to the dark compartment in comparison with control and TMT+PBS groups in 24 hours after shock. Also, time spent in the dark compartment of TMT+DPSCs significantly decreased compared to control and TMT+PBS groups in 24 and 48 hours after shock (P<0.05). Furthermore, DPSCs transplantation significantly decreased the NF-Kβ serum level and percentage of damaged pyramidal neurons of CA1 compared with TMT+PBS (P<0.05). Conclusion: DPSCs transplantation improved memory and learning, regulated NF-Kβ serum level, and decreased damage neurons of CA1 hippocampus in TMT-induced AD rat model." @default.
- W4205383019 created "2022-01-25" @default.
- W4205383019 creator A5001212106 @default.
- W4205383019 creator A5003370351 @default.
- W4205383019 creator A5049882423 @default.
- W4205383019 creator A5051025025 @default.
- W4205383019 date "2021-12-31" @default.
- W4205383019 modified "2023-09-25" @default.
- W4205383019 title "Dental Pulp Stem Cells Transplantation Improves Passive Avoidance Memory and Neuroinflammation in Trimethyltin-Induced Alzheimer’s Disease Rat Model" @default.
- W4205383019 doi "https://doi.org/10.31661/gmj.v10i0.2254" @default.
- W4205383019 hasPublicationYear "2021" @default.
- W4205383019 type Work @default.
- W4205383019 citedByCount "2" @default.
- W4205383019 countsByYear W42053830192023 @default.
- W4205383019 crossrefType "journal-article" @default.
- W4205383019 hasAuthorship W4205383019A5001212106 @default.
- W4205383019 hasAuthorship W4205383019A5003370351 @default.
- W4205383019 hasAuthorship W4205383019A5049882423 @default.
- W4205383019 hasAuthorship W4205383019A5051025025 @default.
- W4205383019 hasBestOaLocation W42053830191 @default.
- W4205383019 hasConcept C126322002 @default.
- W4205383019 hasConcept C142724271 @default.
- W4205383019 hasConcept C16685009 @default.
- W4205383019 hasConcept C198826908 @default.
- W4205383019 hasConcept C2777397205 @default.
- W4205383019 hasConcept C2777400515 @default.
- W4205383019 hasConcept C2779134260 @default.
- W4205383019 hasConcept C2781161787 @default.
- W4205383019 hasConcept C2911091166 @default.
- W4205383019 hasConcept C71924100 @default.
- W4205383019 hasConcept C87753298 @default.
- W4205383019 hasConcept C98274493 @default.
- W4205383019 hasConceptScore W4205383019C126322002 @default.
- W4205383019 hasConceptScore W4205383019C142724271 @default.
- W4205383019 hasConceptScore W4205383019C16685009 @default.
- W4205383019 hasConceptScore W4205383019C198826908 @default.
- W4205383019 hasConceptScore W4205383019C2777397205 @default.
- W4205383019 hasConceptScore W4205383019C2777400515 @default.
- W4205383019 hasConceptScore W4205383019C2779134260 @default.
- W4205383019 hasConceptScore W4205383019C2781161787 @default.
- W4205383019 hasConceptScore W4205383019C2911091166 @default.
- W4205383019 hasConceptScore W4205383019C71924100 @default.
- W4205383019 hasConceptScore W4205383019C87753298 @default.
- W4205383019 hasConceptScore W4205383019C98274493 @default.
- W4205383019 hasLocation W42053830191 @default.
- W4205383019 hasOpenAccess W4205383019 @default.
- W4205383019 hasPrimaryLocation W42053830191 @default.
- W4205383019 hasRelatedWork W103635798 @default.
- W4205383019 hasRelatedWork W2063445979 @default.
- W4205383019 hasRelatedWork W2076760455 @default.
- W4205383019 hasRelatedWork W2110708688 @default.
- W4205383019 hasRelatedWork W2381033493 @default.
- W4205383019 hasRelatedWork W2911459726 @default.
- W4205383019 hasRelatedWork W3023824856 @default.
- W4205383019 hasRelatedWork W3038666778 @default.
- W4205383019 hasRelatedWork W3135238702 @default.
- W4205383019 hasRelatedWork W4248694092 @default.
- W4205383019 hasVolume "10" @default.
- W4205383019 isParatext "false" @default.
- W4205383019 isRetracted "false" @default.
- W4205383019 workType "article" @default.