FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4205431112> ?p ?o ?g. }

• W4205431112 endingPage "153" @default.
• W4205431112 startingPage "153" @default.
• W4205431112 abstract "Over the last few years, several commercial FSH products have been developed for cattle superovulation (SOV) purposes in Multiple Ovulation and Embryo Transfer (MOET) programs. The SOV response is highly variable among individuals and remains one of the main limiting factors in obtaining a profitable number of transferable embryos. In this study, follicle stimulating hormone (FSH) from different origins was included in two SOV protocols, (a) FSH from purified pig pituitary extract (NIH-FSH-p; two doses/day, 12 h apart, four consecutive days); and (b) extra-long-acting bovine recombinant FSH (bscrFSH; a single dose/day, four consecutive days), to test the effects of bscrFSH on the ovarian response, hormone profile levels, in vivo embryo production and the pluripotency gene expression of the obtained embryos. A total of 68 healthy primiparous red Angus cows (Bos taurus) were randomly distributed into two experimental groups (n = 34 each). Blood sample collection for progesterone (P4) and cortisol (C) level determination was performed together with ultrasonographic assessment for ovarian size, follicles (FL) and corpora lutea (CL) quantification in each SOV protocol (Day 0, 4, 8, and 15). Moreover, FSH profiles were monitorised throughout both protocols (Day 0, 4, 5, 6, 7, 8, 9, 10, and 15). In vivo embryo quantity and quality (total structures, morulae, blastocysts, viable, degenerated and blocked embryos) were recorded in each SOV protocol. Finally, embryo quality in both protocols was assessed by the analysis of the expression level of crucial genes for early embryo development (OCT4, IFNt, CDX2, BCL2, and BAX). P4 and cortisol concentration peaks in both SOV protocols were obtained on Day 15 and Day 8, respectively, which were statistically different compared to the other time-points (p < 0.05). Ovarian dimensions increased from Day 0 to Day 15 irrespective of the SOV protocol considered (p < 0.05). Significant changes in CL number were observed over time till Day 15 irrespective of the SOV protocol applied (p < 0.05), being non- significantly different between SOV protocols within each time-point (p > 0.05). The number of CL was higher on Day 15 in the bscrFSH group compared to the NIH-FSH-p group (p < 0.05). The number of embryonic structures recovered was higher in the bscrFSH group (p = 0.025), probably as a result of a tendency towards a greater number of follicles developed compared to the NIH-FSH-p group. IFNt and BAX were overexpressed in embryos from the bscrFSH group (p < 0.05), with a fold change of 16 and 1.3, respectively. However, no statistical differences were detected regarding the OCT4, CDX2, BCL2, and BCL2/BAX expression ratio (p > 0.05). In conclusion, including bscrFSH in SOV protocols could be an important alternative by reducing the number of applications and offering an improved ovarian response together with better embryo quality and superior performance in embryo production compared to NIH-FSH-p SOV protocols." @default.
• W4205431112 created "2022-01-25" @default.
• W4205431112 creator A5008587767 @default.
• W4205431112 creator A5012237779 @default.
• W4205431112 creator A5015840581 @default.
• W4205431112 creator A5025127668 @default.
• W4205431112 creator A5046172171 @default.
• W4205431112 creator A5051472731 @default.
• W4205431112 creator A5065234493 @default.
• W4205431112 creator A5066718032 @default.
• W4205431112 creator A5068013396 @default.
• W4205431112 date "2022-01-09" @default.
• W4205431112 modified "2023-10-06" @default.
• W4205431112 title "Effects of Extra-Long-Acting Recombinant Bovine FSH (bscrFSH) on Cattle Superovulation" @default.
• W4205431112 cites W1486832328 @default.
• W4205431112 cites W1964791997 @default.
• W4205431112 cites W1971910990 @default.
• W4205431112 cites W1972608599 @default.
• W4205431112 cites W1973881680 @default.
• W4205431112 cites W1979517187 @default.
• W4205431112 cites W1979757145 @default.
• W4205431112 cites W1982420400 @default.
• W4205431112 cites W1984117820 @default.
• W4205431112 cites W1986645258 @default.
• W4205431112 cites W1993407620 @default.
• W4205431112 cites W1994447881 @default.
• W4205431112 cites W2002742451 @default.
• W4205431112 cites W2004848920 @default.
• W4205431112 cites W2009350704 @default.
• W4205431112 cites W2012226296 @default.
• W4205431112 cites W2018834054 @default.
• W4205431112 cites W2019140775 @default.
• W4205431112 cites W2021472023 @default.
• W4205431112 cites W2022466431 @default.
• W4205431112 cites W2025323781 @default.
• W4205431112 cites W2031133277 @default.
• W4205431112 cites W2031869781 @default.
• W4205431112 cites W2032669021 @default.
• W4205431112 cites W2033920733 @default.
• W4205431112 cites W2036787629 @default.
• W4205431112 cites W2037801566 @default.
• W4205431112 cites W2040379275 @default.
• W4205431112 cites W2040592705 @default.
• W4205431112 cites W2040653237 @default.
• W4205431112 cites W2043504189 @default.
• W4205431112 cites W2051391167 @default.
• W4205431112 cites W2054318159 @default.
• W4205431112 cites W2056397474 @default.
• W4205431112 cites W2057546534 @default.
• W4205431112 cites W2063815493 @default.
• W4205431112 cites W2078194191 @default.
• W4205431112 cites W2082512936 @default.
• W4205431112 cites W2082605617 @default.
• W4205431112 cites W2085648635 @default.
• W4205431112 cites W2090886030 @default.
• W4205431112 cites W2098515713 @default.
• W4205431112 cites W2099387383 @default.
• W4205431112 cites W2104960054 @default.
• W4205431112 cites W2105720728 @default.
• W4205431112 cites W2111132006 @default.
• W4205431112 cites W2113477073 @default.
• W4205431112 cites W2122510033 @default.
• W4205431112 cites W2123025773 @default.
• W4205431112 cites W2124516743 @default.
• W4205431112 cites W2130942583 @default.
• W4205431112 cites W2133820412 @default.
• W4205431112 cites W2142043767 @default.
• W4205431112 cites W2148016791 @default.
• W4205431112 cites W2150510209 @default.
• W4205431112 cites W2150539937 @default.
• W4205431112 cites W2152094605 @default.
• W4205431112 cites W2154439227 @default.
• W4205431112 cites W2158553653 @default.
• W4205431112 cites W2159380180 @default.
• W4205431112 cites W2163472216 @default.
• W4205431112 cites W2165236774 @default.
• W4205431112 cites W2171487969 @default.
• W4205431112 cites W2207345824 @default.
• W4205431112 cites W2413584729 @default.
• W4205431112 cites W2416721159 @default.
• W4205431112 cites W2517079279 @default.
• W4205431112 cites W2618900678 @default.
• W4205431112 cites W2756712110 @default.
• W4205431112 cites W2770117147 @default.
• W4205431112 cites W2792547568 @default.
• W4205431112 cites W2882975421 @default.
• W4205431112 cites W2892505670 @default.
• W4205431112 cites W2912503596 @default.
• W4205431112 cites W2968857155 @default.
• W4205431112 cites W2970932163 @default.
• W4205431112 cites W2979077613 @default.
• W4205431112 cites W2992704927 @default.
• W4205431112 cites W2999533766 @default.
• W4205431112 cites W3006749604 @default.
• W4205431112 cites W3015318640 @default.
• W4205431112 cites W3022099511 @default.
• W4205431112 cites W3026047275 @default.
• W4205431112 cites W3045223849 @default.

• next