Matches in SemOpenAlex for { <https://semopenalex.org/work/W4205434160> ?p ?o ?g. }
- W4205434160 endingPage "444" @default.
- W4205434160 startingPage "432" @default.
- W4205434160 abstract "Abstract Tumour growth and dissemination is largely dependent on nutrient availability. It has recently emerged that the tumour microenvironment is rich in a diverse array of lipids that increase in abundance with tumour progression and play a role in promoting tumour growth and metastasis. Here, we describe the pro-tumorigenic roles of lipid uptake, metabolism and synthesis and detail the therapeutic potential of targeting lipid metabolism in cancer. Additionally, we highlight new insights into the distinct immunosuppressive effects of lipids in the tumour microenvironment. Lipids threaten an anti-tumour environment whereby metabolic adaptation to lipid metabolism is linked to immune dysfunction. Finally, we describe the differential effects of commondietary lipids on cancer growth which may uncover a role for specific dietary regimens in association with traditional cancer therapies. Understanding the relationship between dietary lipids, tumour, and immune cells is important in the context of obesity which may reveal a possibility to harness the diet in the treatment of cancers." @default.
- W4205434160 created "2022-01-25" @default.
- W4205434160 creator A5013280039 @default.
- W4205434160 creator A5082399313 @default.
- W4205434160 date "2022-01-05" @default.
- W4205434160 modified "2023-10-17" @default.
- W4205434160 title "Diet, lipids, and antitumor immunity" @default.
- W4205434160 cites W1470433217 @default.
- W4205434160 cites W1508675434 @default.
- W4205434160 cites W1516464304 @default.
- W4205434160 cites W1663833839 @default.
- W4205434160 cites W1853287186 @default.
- W4205434160 cites W1919595924 @default.
- W4205434160 cites W1971301031 @default.
- W4205434160 cites W1973417968 @default.
- W4205434160 cites W1976555781 @default.
- W4205434160 cites W1978281808 @default.
- W4205434160 cites W1985592156 @default.
- W4205434160 cites W1986234170 @default.
- W4205434160 cites W1997779912 @default.
- W4205434160 cites W2002490399 @default.
- W4205434160 cites W2006401124 @default.
- W4205434160 cites W2009170266 @default.
- W4205434160 cites W2014671368 @default.
- W4205434160 cites W2015308396 @default.
- W4205434160 cites W2016868307 @default.
- W4205434160 cites W2023947368 @default.
- W4205434160 cites W2025639892 @default.
- W4205434160 cites W2028621708 @default.
- W4205434160 cites W2032860037 @default.
- W4205434160 cites W2041237929 @default.
- W4205434160 cites W2042965540 @default.
- W4205434160 cites W2044748328 @default.
- W4205434160 cites W2051393353 @default.
- W4205434160 cites W2059273277 @default.
- W4205434160 cites W2063632665 @default.
- W4205434160 cites W2064484411 @default.
- W4205434160 cites W2070432942 @default.
- W4205434160 cites W2070745672 @default.
- W4205434160 cites W2075209047 @default.
- W4205434160 cites W2077181241 @default.
- W4205434160 cites W2088253442 @default.
- W4205434160 cites W2088545470 @default.
- W4205434160 cites W2088828925 @default.
- W4205434160 cites W2089532303 @default.
- W4205434160 cites W2090846942 @default.
- W4205434160 cites W2094093571 @default.
- W4205434160 cites W2095591310 @default.
- W4205434160 cites W2096435906 @default.
- W4205434160 cites W2099483065 @default.
- W4205434160 cites W2099635702 @default.
- W4205434160 cites W2100039832 @default.
- W4205434160 cites W2104104624 @default.
- W4205434160 cites W2104724110 @default.
- W4205434160 cites W2107934786 @default.
- W4205434160 cites W2116504531 @default.
- W4205434160 cites W2122446546 @default.
- W4205434160 cites W2129205142 @default.
- W4205434160 cites W2134917812 @default.
- W4205434160 cites W2135669945 @default.
- W4205434160 cites W2138331892 @default.
- W4205434160 cites W2138709778 @default.
- W4205434160 cites W2143408204 @default.
- W4205434160 cites W2143750439 @default.
- W4205434160 cites W2146607058 @default.
- W4205434160 cites W2150678612 @default.
- W4205434160 cites W2153071631 @default.
- W4205434160 cites W2153178365 @default.
- W4205434160 cites W2154528654 @default.
- W4205434160 cites W2156145814 @default.
- W4205434160 cites W2157817725 @default.
- W4205434160 cites W2160551785 @default.
- W4205434160 cites W2160715047 @default.
- W4205434160 cites W2161175621 @default.
- W4205434160 cites W2189205651 @default.
- W4205434160 cites W2193074466 @default.
- W4205434160 cites W2276842451 @default.
- W4205434160 cites W2290001148 @default.
- W4205434160 cites W2299840252 @default.
- W4205434160 cites W2344037260 @default.
- W4205434160 cites W2523687917 @default.
- W4205434160 cites W2560396365 @default.
- W4205434160 cites W2580767461 @default.
- W4205434160 cites W2588856093 @default.
- W4205434160 cites W2741524908 @default.
- W4205434160 cites W2755181857 @default.
- W4205434160 cites W2755907400 @default.
- W4205434160 cites W2757435464 @default.
- W4205434160 cites W2763053047 @default.
- W4205434160 cites W2884166738 @default.
- W4205434160 cites W2891551269 @default.
- W4205434160 cites W2899984019 @default.
- W4205434160 cites W2903107073 @default.
- W4205434160 cites W2904307134 @default.
- W4205434160 cites W2909240409 @default.
- W4205434160 cites W2916262950 @default.
- W4205434160 cites W2917853396 @default.
- W4205434160 cites W2918938634 @default.