Matches in SemOpenAlex for { <https://semopenalex.org/work/W4205435790> ?p ?o ?g. }
Showing items 1 to 91 of
91
with 100 items per page.
- W4205435790 endingPage "17" @default.
- W4205435790 startingPage "1" @default.
- W4205435790 abstract "The human bronchial epithelial cells (HBE) and K-ras-silenced HBE cells were treated with fine particulate matter (PM2.5) samples from Taiyuan for 24 h. To screen the proteomic characteristics of PM2.5-induced differentially expressed proteins (DEPs), the Q Exactive mass spectrometer was used. Gene ontology (GO) analysis, Kyoto encyclopedia of genes and genomes (KEGG) analysis, functional prediction, protein-protein interaction (PPI) network analysis, and visualization of differential protein interactions were performed. 251 DEPs in K-ras silenced cells and 535 DEPs in normal HBE cells were identified, respectively. KEGG analysis showed that the differentially expressed proteins of PM2.5-treated cells were related to the biosynthesis of ribosomes, antibiotics, and amino acids. On the other hand, K-ras silenced cells were related to metabolic pathways, RNA transport, and DNA replication. Through the construction of a PPI network, the top 10 hub proteins were screened from the two cell groups, among which MRPL13, RPS20, and EIF1AX were of great significance. Our results indicated that the K-ras gene plays an important role in PM2.5-induced DEPs, and the findings provide a scientific basis for the further study of PM2.5 toxic mechanisms and biomarkers." @default.
- W4205435790 created "2022-01-25" @default.
- W4205435790 creator A5003870203 @default.
- W4205435790 creator A5010655262 @default.
- W4205435790 creator A5014426597 @default.
- W4205435790 creator A5019978395 @default.
- W4205435790 creator A5020883194 @default.
- W4205435790 creator A5031501797 @default.
- W4205435790 creator A5080846142 @default.
- W4205435790 date "2022-01-11" @default.
- W4205435790 modified "2023-09-28" @default.
- W4205435790 title "Proteomic characteristics of PM2.5-induced differentially expressed proteins in k-ras-silenced HBE cells" @default.
- W4205435790 cites W1971467793 @default.
- W4205435790 cites W1980353330 @default.
- W4205435790 cites W1995295362 @default.
- W4205435790 cites W2061718426 @default.
- W4205435790 cites W2070664727 @default.
- W4205435790 cites W2126393044 @default.
- W4205435790 cites W2135184154 @default.
- W4205435790 cites W2139873559 @default.
- W4205435790 cites W2141970008 @default.
- W4205435790 cites W2338299962 @default.
- W4205435790 cites W2339754828 @default.
- W4205435790 cites W2570368090 @default.
- W4205435790 cites W2607350314 @default.
- W4205435790 cites W2617191149 @default.
- W4205435790 cites W2653933210 @default.
- W4205435790 cites W2753179981 @default.
- W4205435790 cites W2771135918 @default.
- W4205435790 cites W2793014591 @default.
- W4205435790 cites W2896801540 @default.
- W4205435790 cites W2897084511 @default.
- W4205435790 cites W2921771746 @default.
- W4205435790 cites W2935938593 @default.
- W4205435790 cites W2989076687 @default.
- W4205435790 doi "https://doi.org/10.1080/15376516.2022.2028328" @default.
- W4205435790 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35014587" @default.
- W4205435790 hasPublicationYear "2022" @default.
- W4205435790 type Work @default.
- W4205435790 citedByCount "0" @default.
- W4205435790 crossrefType "journal-article" @default.
- W4205435790 hasAuthorship W4205435790A5003870203 @default.
- W4205435790 hasAuthorship W4205435790A5010655262 @default.
- W4205435790 hasAuthorship W4205435790A5014426597 @default.
- W4205435790 hasAuthorship W4205435790A5019978395 @default.
- W4205435790 hasAuthorship W4205435790A5020883194 @default.
- W4205435790 hasAuthorship W4205435790A5031501797 @default.
- W4205435790 hasAuthorship W4205435790A5080846142 @default.
- W4205435790 hasConcept C104317684 @default.
- W4205435790 hasConcept C150194340 @default.
- W4205435790 hasConcept C152724338 @default.
- W4205435790 hasConcept C153911025 @default.
- W4205435790 hasConcept C2987395477 @default.
- W4205435790 hasConcept C46111723 @default.
- W4205435790 hasConcept C55493867 @default.
- W4205435790 hasConcept C67705224 @default.
- W4205435790 hasConcept C70721500 @default.
- W4205435790 hasConcept C86803240 @default.
- W4205435790 hasConcept C88478588 @default.
- W4205435790 hasConcept C95444343 @default.
- W4205435790 hasConceptScore W4205435790C104317684 @default.
- W4205435790 hasConceptScore W4205435790C150194340 @default.
- W4205435790 hasConceptScore W4205435790C152724338 @default.
- W4205435790 hasConceptScore W4205435790C153911025 @default.
- W4205435790 hasConceptScore W4205435790C2987395477 @default.
- W4205435790 hasConceptScore W4205435790C46111723 @default.
- W4205435790 hasConceptScore W4205435790C55493867 @default.
- W4205435790 hasConceptScore W4205435790C67705224 @default.
- W4205435790 hasConceptScore W4205435790C70721500 @default.
- W4205435790 hasConceptScore W4205435790C86803240 @default.
- W4205435790 hasConceptScore W4205435790C88478588 @default.
- W4205435790 hasConceptScore W4205435790C95444343 @default.
- W4205435790 hasLocation W42054357901 @default.
- W4205435790 hasLocation W42054357902 @default.
- W4205435790 hasOpenAccess W4205435790 @default.
- W4205435790 hasPrimaryLocation W42054357901 @default.
- W4205435790 hasRelatedWork W2001670874 @default.
- W4205435790 hasRelatedWork W2352070969 @default.
- W4205435790 hasRelatedWork W2909382709 @default.
- W4205435790 hasRelatedWork W2962330546 @default.
- W4205435790 hasRelatedWork W3134676575 @default.
- W4205435790 hasRelatedWork W3135849929 @default.
- W4205435790 hasRelatedWork W3166643060 @default.
- W4205435790 hasRelatedWork W3187288173 @default.
- W4205435790 hasRelatedWork W4205963003 @default.
- W4205435790 hasRelatedWork W4210625724 @default.
- W4205435790 isParatext "false" @default.
- W4205435790 isRetracted "false" @default.
- W4205435790 workType "article" @default.