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- W4205485768 abstract "1% topical 5-fluorouracil (5-FU) is a treatment for ocular surface squamous neoplasia (OSSN) due to its effectiveness, low cost, and tolerable side effect profile. To our knowledge there is no reported sight-threatening corneal complication of 1% 5-FU for the treatment of OSSN.We report a 78 year-old man with bilateral conjunctival intraepithelial neoplasia (CIN) who developed bilateral corneoscleral ulceration and corneal perforation of the left eye after 1% 5-FU topical treatment.Our case report describes serious potential complications of 1% 5-FU, reviews possible risk factors associated with poor outcomes, and discusses our treatment approach." @default.
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- W4205485768 date "2022-03-01" @default.
- W4205485768 modified "2023-10-01" @default.
- W4205485768 title "A case of sight threatening complications from topical 1% 5-fluorouracil in the treatment of ocular surface squamous neoplasia" @default.
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- W4205485768 doi "https://doi.org/10.1016/j.ajoc.2022.101265" @default.
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