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• W4205575087 abstract "Abstract A mild direct synthesis of chiral imidazo[2,1‐ a ]isoquinolin‐3‐one derivatives with dihydroisoquinolines and N ‐substituted amino acids have been developed. By the use of easily accessible DCC as condensation reagent at ambient temperature, a series of imidazo[2,1‐ a ]isoquinolin‐3‐ones can be assembled readily in low to good yields with low to excellent dr values. Interestingly, the use of N ‐substituted L ‐Threonine and L ‐Serine afforded oxazino[2,3‐ a ]isoquinolin‐4‐one derivatives with good diastereoselectivities." @default.
• W4205575087 created "2022-01-26" @default.
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• W4205575087 date "2022-01-28" @default.
• W4205575087 modified "2023-10-14" @default.
• W4205575087 title "Asymmetric Synthesis of Imidazo[2,1‐<i>a</i>]isoquinolin‐3‐ones with Dihydroisoquinolines and <i>N</i>‐substituted Amino Acids" @default.
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• W4205575087 doi "https://doi.org/10.1002/ajoc.202100761" @default.
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