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- W4205584952 abstract "Thioglycoside werden weithin als kompetitive Inhibitoren von Glycosidasen eingesetzt. Nun wurde mit BglT, einer 6-Phospho-β-glucosidase aus der Glucosidase-Familie 4, die erste Glycosidase entdeckt, die nichtaktivierte Thioglycoside hydrolysiert. Die effiziente Spaltung der Thioglycosid-Bindung beruht auf dem α,β-Eliminierungsmechanismus der GH4-Enzyme, der sich von den nucleophilen Verdrängungsmechanismen „klassischer“ Glycosidasen unterscheidet." @default.
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- W4205584952 date "2006-09-18" @default.
- W4205584952 modified "2023-10-18" @default.
- W4205584952 title "Family 4 Glycosidases Carry Out Efficient Hydrolysis of Thioglycosides by an α,β-Elimination Mechanism" @default.
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- W4205584952 doi "https://doi.org/10.1002/ange.200601421" @default.
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