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- W4205599225 abstract "In pregnancy, if the woman has a cardiovascular disease, her fetus has an increased risk of inherited cardiac genetic disorders. Aim of this study was to evaluate electrocardiographic alternans (ECGA, <tex>$mu V)$</tex> of 23 pregnant women, comparing 12 mothers of fetuses with normal rhythm (Mum_NRF) and 11 mothers of arrhythmic fetuses (Mum_ArrF). ECGA is a noninvasive cardiac electrical risk marker able to reveal heart electrical instability. ECGA manifests in the ECG as P-wave alternans (PWA), QRS alternans (QRSA) and/or T-wave alternans (TWA). Analysis was performed by the enhanced adaptive matched filter method. ECGA distributions were expressed as: median (interquartile range). Comparisons were performed by the Wilcoxon rank-sum test. Although showing similar heart rate (Mum_NRF: 85 (19) bpm; Mum_ArrF: 90 (13) bpm), ECGA was higher in Mum_ArrF population than Mum_NRF one (PWA: 9 (7) <tex>$mu V vs. 14 (14) mu V;$</tex> QRSA: 9 (10) <tex>$mu V vs$</tex> . 17 (16) <tex>$mu V$,</tex> TWA: 12 (14) <tex>$mu Vvs. 28(17) mu V)$</tex>, but only TWA distributions were statistically different. Moreover, TWA was higher than in a female healthy population (on average <tex>$18mu V)$</tex>in 70% of Mum_ArrF, vs. 33% of Mum_NRF. Thus, higher TWA in our Mum_ArrF seems to reflect a more unstable heart electrical condition of arrhythmic fetuses' mothers than normal-rhythm fetuses' mothers." @default.
- W4205599225 created "2022-01-25" @default.
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- W4205599225 date "2021-09-13" @default.
- W4205599225 modified "2023-10-14" @default.
- W4205599225 title "Cardiac Electrical Alternans in Pregnancy: an Observational Study" @default.
- W4205599225 doi "https://doi.org/10.23919/cinc53138.2021.9662936" @default.
- W4205599225 hasPublicationYear "2021" @default.
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