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• W4205602807 endingPage "208" @default.
• W4205602807 startingPage "198" @default.
• W4205602807 abstract "Bio-inspired nanostructures have demonstrated highly efficient mechano-bactericidal performances with no risk of bacterial resistance; however, they are prone to become contaminated with the killed bacterial debris. Herein, a biocompatible mechano-bactericidal nanopatterned surface with salt-responsive bacterial releasing behavior is developed by grafting salt-responsive polyzwitterionic (polyDVBAPS) brushes on a bio-inspired nanopattern surface. Benefiting from the salt-triggered configuration change of the grafted polymer brushes, this dual-functional surface shows high mechano-bactericidal efficiency in water (low ionic strength condition), while the dead bacterial residuals can be easily lifted by the extended polymer chains and removed from the surface in 1 M NaCl solution (high ionic strength conditions). Notably, this functionalized nanopatterned surface shows selective biocidal activity between bacterial cells sand eukaryotic cells. The biocompatibility with red blood cells (RBCs) and mammalian cells was tested in vitro. The histocompatibility and prevention of perioperative contamination activity were verified by in vivo evaluation in a rat subcutaneous implant model. This nanopatterned surface with bacterial killing and releasing activities may open new avenues for designing bio-inspired mechano-bactericidal platforms with long-term efficacy, thus presenting a facile alternative in combating perioperative-related bacterial infection. STATEMENT OF SIGNIFICANCE: Bioinspired nanostructured surfaces with noticeable mechano-bactericidal activity showed great potential in moderating drug-resistance. However, the nanopatterned surfaces are prone to be contaminated by the killed bacterial debris and compromised the bactericidal performance. In this study, we provide a dual-functional antibacterial conception with both mechano-bactericidal and bacterial releasing performances not requiring external chemical bactericidal agents. Additionally, this functionalized antibacterial surface also shows selective biocidal activity between bacteria and eukaryotic cells, and the excellent biocompatibility was tested in vitro and in vivo. The new concept for the functionalized mechano-bactericidal surface here illustrated presents a facile antibiotic-free alternative in combating perioperative related bacterial infection in practical application." @default.
• W4205602807 created "2022-01-26" @default.
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• W4205602807 date "2022-03-01" @default.
• W4205602807 modified "2023-09-27" @default.
• W4205602807 title "Biocompatible mechano-bactericidal nanopatterned surfaces with salt-responsive bacterial release" @default.
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• W4205602807 cites W2041233437 @default.
• W4205602807 cites W2064837586 @default.
• W4205602807 cites W2081116099 @default.
• W4205602807 cites W2101150914 @default.
• W4205602807 cites W2109168464 @default.
• W4205602807 cites W2165462684 @default.
• W4205602807 cites W2312256138 @default.
• W4205602807 cites W2316291022 @default.
• W4205602807 cites W2331169062 @default.
• W4205602807 cites W2331466524 @default.
• W4205602807 cites W2503937957 @default.
• W4205602807 cites W2512386503 @default.
• W4205602807 cites W2514410094 @default.
• W4205602807 cites W2566024832 @default.
• W4205602807 cites W2568063596 @default.
• W4205602807 cites W2584326054 @default.
• W4205602807 cites W2729365320 @default.
• W4205602807 cites W2734204398 @default.
• W4205602807 cites W2737647680 @default.
• W4205602807 cites W2740273888 @default.
• W4205602807 cites W2746188371 @default.
• W4205602807 cites W2756524037 @default.
• W4205602807 cites W2759270146 @default.
• W4205602807 cites W2793320126 @default.
• W4205602807 cites W2795571145 @default.
• W4205602807 cites W2799518824 @default.
• W4205602807 cites W2803023910 @default.
• W4205602807 cites W2804299921 @default.
• W4205602807 cites W2806283015 @default.
• W4205602807 cites W2808063852 @default.
• W4205602807 cites W2893419411 @default.
• W4205602807 cites W2896969491 @default.
• W4205602807 cites W2910335439 @default.
• W4205602807 cites W2917489700 @default.
• W4205602807 cites W2922314157 @default.
• W4205602807 cites W2938565066 @default.
• W4205602807 cites W2942679330 @default.
• W4205602807 cites W2947982460 @default.
• W4205602807 cites W2949733923 @default.
• W4205602807 cites W2961484319 @default.
• W4205602807 cites W2968702285 @default.
• W4205602807 cites W2972045967 @default.
• W4205602807 cites W2976698134 @default.
• W4205602807 cites W3000645697 @default.
• W4205602807 cites W3006916659 @default.
• W4205602807 cites W3009309823 @default.
• W4205602807 cites W3011076157 @default.
• W4205602807 cites W3011566611 @default.
• W4205602807 cites W3011946934 @default.
• W4205602807 cites W3017568006 @default.
• W4205602807 cites W3025113036 @default.
• W4205602807 cites W3030047074 @default.
• W4205602807 cites W3032717961 @default.
• W4205602807 cites W3037281236 @default.
• W4205602807 cites W3038188576 @default.
• W4205602807 cites W3047373209 @default.
• W4205602807 cites W3048987220 @default.
• W4205602807 cites W3066539718 @default.
• W4205602807 cites W3082848166 @default.
• W4205602807 cites W3112438286 @default.
• W4205602807 cites W3112988804 @default.
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• W4205602807 cites W3119090414 @default.
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• W4205602807 doi "https://doi.org/10.1016/j.actbio.2022.01.038" @default.
• W4205602807 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35066170" @default.
• W4205602807 hasPublicationYear "2022" @default.
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