FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4205651235> ?p ?o ?g. }

• W4205651235 endingPage "40050" @default.
• W4205651235 startingPage "40040" @default.
• W4205651235 abstract "Two new dinuclear copper(ii) complexes, [Cu(ambt)2(cnba)4] (1) and [Cu(ambt)2(clba)4] (2) were synthesized with 2-amino-6-methoxybenzothiazole (ambt) as the main ligand. The structures of the two complexes were characterized by single-crystal XRD. The binding between CT-DNA (calf thymus DNA) and the complexes was evaluated by viscometry, electronic absorption, and fluorescence spectroscopy, and the binding constants were calculated using the Stern-Volmer equation. The complexes were intercalatively bound to CT-DNA, and [Cu(ambt)2(clba)4] having a greater binding constant than [Cu(ambt)2(cnba)4]. The two complexes had better antitumor properties against HepG2 (human hepatocellular carcinoma), A549 (human lung carcinoma), and HeLa (human cervical carcinoma) tumor cell lines than their respective ligands and cisplatin. Furthermore, [Cu(ambt)2(clba)4] had a stronger inhibitory ability on the three types of tumor cells than [Cu(ambt)2(cnba)4], which is congruent with the binding power of the complexes with DNA. Flow cytometry revealed that [Cu(ambt)2(cnba)4] and [Cu(ambt)2(clba)4] could trigger apoptosis or necrosis, arrest the HepG2 cell cycles, and cause G0/G1-phase cells to accumulate." @default.
• W4205651235 created "2022-01-26" @default.
• W4205651235 creator A5012776991 @default.
• W4205651235 creator A5016774469 @default.
• W4205651235 creator A5017287411 @default.
• W4205651235 creator A5057029172 @default.
• W4205651235 creator A5064221639 @default.
• W4205651235 creator A5083362538 @default.
• W4205651235 creator A5091271520 @default.
• W4205651235 date "2021-01-01" @default.
• W4205651235 modified "2023-10-15" @default.
• W4205651235 title "Synthesis, crystal structures, DNA interactions, and antitumor activity of two new dinuclear copper(<scp>ii</scp>) complexes with thiazole ligand" @default.
• W4205651235 cites W1926197274 @default.
• W4205651235 cites W1989279677 @default.
• W4205651235 cites W1993705187 @default.
• W4205651235 cites W2083910101 @default.
• W4205651235 cites W2207249069 @default.
• W4205651235 cites W2617247096 @default.
• W4205651235 cites W2789388339 @default.
• W4205651235 cites W2803088715 @default.
• W4205651235 cites W2804663836 @default.
• W4205651235 cites W2897373502 @default.
• W4205651235 cites W2901794543 @default.
• W4205651235 cites W2903043456 @default.
• W4205651235 cites W2908057150 @default.
• W4205651235 cites W2911351536 @default.
• W4205651235 cites W2911988543 @default.
• W4205651235 cites W2912946765 @default.
• W4205651235 cites W2916172006 @default.
• W4205651235 cites W2916551568 @default.
• W4205651235 cites W2918300848 @default.
• W4205651235 cites W2925309190 @default.
• W4205651235 cites W2939039907 @default.
• W4205651235 cites W2947129118 @default.
• W4205651235 cites W2947242945 @default.
• W4205651235 cites W2949765486 @default.
• W4205651235 cites W2965008467 @default.
• W4205651235 cites W2965274129 @default.
• W4205651235 cites W2966319883 @default.
• W4205651235 cites W2967387861 @default.
• W4205651235 cites W2968601624 @default.
• W4205651235 cites W2978570402 @default.
• W4205651235 cites W2982093780 @default.
• W4205651235 cites W2993518417 @default.
• W4205651235 cites W3000693448 @default.
• W4205651235 cites W3008759678 @default.
• W4205651235 cites W3009155911 @default.
• W4205651235 cites W3013880442 @default.
• W4205651235 cites W3017296353 @default.
• W4205651235 cites W3020342666 @default.
• W4205651235 cites W3020599379 @default.
• W4205651235 cites W3022742868 @default.
• W4205651235 cites W3031903021 @default.
• W4205651235 cites W3038755182 @default.
• W4205651235 cites W3045305241 @default.
• W4205651235 cites W3048200221 @default.
• W4205651235 cites W3089455016 @default.
• W4205651235 cites W3114527437 @default.
• W4205651235 cites W3119098507 @default.
• W4205651235 cites W3176994273 @default.
• W4205651235 cites W3196585746 @default.
• W4205651235 doi "https://doi.org/10.1039/d1ra05798g" @default.
• W4205651235 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35494110" @default.
• W4205651235 hasPublicationYear "2021" @default.
• W4205651235 type Work @default.
• W4205651235 citedByCount "8" @default.
• W4205651235 countsByYear W42056512352022 @default.
• W4205651235 countsByYear W42056512352023 @default.
• W4205651235 crossrefType "journal-article" @default.
• W4205651235 hasAuthorship W4205651235A5012776991 @default.
• W4205651235 hasAuthorship W4205651235A5016774469 @default.
• W4205651235 hasAuthorship W4205651235A5017287411 @default.
• W4205651235 hasAuthorship W4205651235A5057029172 @default.
• W4205651235 hasAuthorship W4205651235A5064221639 @default.
• W4205651235 hasAuthorship W4205651235A5083362538 @default.
• W4205651235 hasAuthorship W4205651235A5091271520 @default.
• W4205651235 hasBestOaLocation W42056512351 @default.
• W4205651235 hasConcept C107824862 @default.
• W4205651235 hasConcept C116569031 @default.
• W4205651235 hasConcept C1491633281 @default.
• W4205651235 hasConcept C153911025 @default.
• W4205651235 hasConcept C170493617 @default.
• W4205651235 hasConcept C178790620 @default.
• W4205651235 hasConcept C185592680 @default.
• W4205651235 hasConcept C190283241 @default.
• W4205651235 hasConcept C2776694085 @default.
• W4205651235 hasConcept C2777366897 @default.
• W4205651235 hasConcept C2778239845 @default.
• W4205651235 hasConcept C2778464347 @default.
• W4205651235 hasConcept C29537977 @default.
• W4205651235 hasConcept C32786932 @default.
• W4205651235 hasConcept C54355233 @default.
• W4205651235 hasConcept C544778455 @default.
• W4205651235 hasConcept C552990157 @default.
• W4205651235 hasConcept C553184892 @default.
• W4205651235 hasConcept C55493867 @default.
• W4205651235 hasConcept C71240020 @default.
• W4205651235 hasConcept C8010536 @default.

• next