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- W4205658577 abstract "Effect of 14-day head up bedrest (HUBR) on the human orthostatic tolerance studied with participation of 23 essentially healthy male subjects at the age of 18 to 35 years. HUBR with the head-end tilted up at +9.6º was to imitate physiological effects of the lunar gravity. Orthostatic tolerance was tested on the day prior to and immediately after HUBR completion with subjects tilted up to +70° for 20 min maximum. The parameters registered before, during and after the tilt test included blood pressure, ECG and heart rate. In comparison with the baseline testing, HUBR reduced the number of completed tests and increased the number (10 vs. 4) of tests terminated for the reason of precollapse (p < 0.05). The group mean time of OS test tolerance decreased by 3.8 minutes (p < 0.01) and time interval between the test onset and precollapse decreased by 4.7 minutes (p = 0.055). For the most part, orthostatic disorders following HUBR were described as a vasodepressor type hypotension collapse with high activity of the chronotropic function of the heart. Several cases of vagus-mediated HR slowing pointed to a sharp decline of the sympathetic nervous activity which is an important mechanism of hemodynamics regulation in changed postural conditions." @default.
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- W4205658577 date "2021-01-01" @default.
- W4205658577 modified "2023-09-26" @default.
- W4205658577 title "EFFECT OF 14-DAY HEAD UP BEDREST ON ORTHOSTATIC TOLERANCE IN HUMANS" @default.
- W4205658577 doi "https://doi.org/10.21687/0233-528x-2021-55-6-42-49" @default.
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