FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4205698172> ?p ?o ?g. }

• W4205698172 abstract "While there is substantial evidence that cannabis use is associated with differences in brain structure and function, most of this evidence is correlational in nature. This is particularly true regarding the association of adolescent cannabis use on human brain development, which cannot be tested in an experimental approach. Bayesian causal network (BCN) modeling attempts to identify probable causal associations in correlational data by using the conditional probabilities among a set of interrelated variables to estimate directional associations between those variables. The current report builds on a recent analysis conducted by Albaugh et al. (2021) that found an association between neurodevelopment and cannabis use in the IMAGEN study of adolescent brain development. Here, we employ BCN modeling on the same sample to provide evidence that the associations found previously are driven by cannabis use affecting neurodevelopment and not, for example, by a pre-existing neurodevelopmental trajectory that also promotes cannabis use. Structural MRI was acquired at ages 14 and 19, from which average cortical thickness was derived for a region of interest in the dorsal prefrontal cortex identified by Albaugh et al. as differing in adolescents who initiated cannabis use between ages 14 and 19. Adolescents were all cannabis naïve at age 14 and 46% had used cannabis at least once by age 19. We tested multiple learning algorithms with a variety of different parameters to build BCNs that would describe the relationship between cortical thickness and cannabis use. All BCN models strongly suggested a directional relationship from cannabis use between the ages of 14 and 19 to accelerated cortical thinning during that same period. Acknowledging that BCN modeling cannot prove a causal relationship between adolescent cannabis use and accelerated cortical thinning, these results are consistent with a body of preclinical and human research suggesting that adolescent cannabis use adversely affects brain development." @default.
• W4205698172 created "2022-01-25" @default.
• W4205698172 creator A5000701045 @default.
• W4205698172 creator A5000742405 @default.
• W4205698172 creator A5001775538 @default.
• W4205698172 creator A5007613571 @default.
• W4205698172 creator A5008874281 @default.
• W4205698172 creator A5009653914 @default.
• W4205698172 creator A5011854403 @default.
• W4205698172 creator A5016008616 @default.
• W4205698172 creator A5028382889 @default.
• W4205698172 creator A5029387054 @default.
• W4205698172 creator A5030737970 @default.
• W4205698172 creator A5031434226 @default.
• W4205698172 creator A5036317033 @default.
• W4205698172 creator A5037097660 @default.
• W4205698172 creator A5046043754 @default.
• W4205698172 creator A5047801362 @default.
• W4205698172 creator A5051365781 @default.
• W4205698172 creator A5054161290 @default.
• W4205698172 creator A5056594157 @default.
• W4205698172 creator A5058399846 @default.
• W4205698172 creator A5059687987 @default.
• W4205698172 creator A5060772200 @default.
• W4205698172 creator A5061352061 @default.
• W4205698172 creator A5063406820 @default.
• W4205698172 creator A5075640613 @default.
• W4205698172 creator A5076055248 @default.
• W4205698172 creator A5078542383 @default.
• W4205698172 creator A5081659034 @default.
• W4205698172 creator A5082198148 @default.
• W4205698172 creator A5083966256 @default.
• W4205698172 creator A5085160808 @default.
• W4205698172 creator A5085832913 @default.
• W4205698172 creator A5090364896 @default.
• W4205698172 date "2021-08-09" @default.
• W4205698172 modified "2023-10-17" @default.
• W4205698172 title "Bayesian Causal Network Modeling Suggests Adolescent Cannabis Use Promotes Accelerated Prefrontal Cortical Thinning" @default.
• W4205698172 doi "https://doi.org/10.31234/osf.io/2fzjp" @default.
• W4205698172 hasPublicationYear "2021" @default.
• W4205698172 type Work @default.
• W4205698172 citedByCount "0" @default.
• W4205698172 crossrefType "posted-content" @default.
• W4205698172 hasAuthorship W4205698172A5000701045 @default.
• W4205698172 hasAuthorship W4205698172A5000742405 @default.
• W4205698172 hasAuthorship W4205698172A5001775538 @default.
• W4205698172 hasAuthorship W4205698172A5007613571 @default.
• W4205698172 hasAuthorship W4205698172A5008874281 @default.
• W4205698172 hasAuthorship W4205698172A5009653914 @default.
• W4205698172 hasAuthorship W4205698172A5011854403 @default.
• W4205698172 hasAuthorship W4205698172A5016008616 @default.
• W4205698172 hasAuthorship W4205698172A5028382889 @default.
• W4205698172 hasAuthorship W4205698172A5029387054 @default.
• W4205698172 hasAuthorship W4205698172A5030737970 @default.
• W4205698172 hasAuthorship W4205698172A5031434226 @default.
• W4205698172 hasAuthorship W4205698172A5036317033 @default.
• W4205698172 hasAuthorship W4205698172A5037097660 @default.
• W4205698172 hasAuthorship W4205698172A5046043754 @default.
• W4205698172 hasAuthorship W4205698172A5047801362 @default.
• W4205698172 hasAuthorship W4205698172A5051365781 @default.
• W4205698172 hasAuthorship W4205698172A5054161290 @default.
• W4205698172 hasAuthorship W4205698172A5056594157 @default.
• W4205698172 hasAuthorship W4205698172A5058399846 @default.
• W4205698172 hasAuthorship W4205698172A5059687987 @default.
• W4205698172 hasAuthorship W4205698172A5060772200 @default.
• W4205698172 hasAuthorship W4205698172A5061352061 @default.
• W4205698172 hasAuthorship W4205698172A5063406820 @default.
• W4205698172 hasAuthorship W4205698172A5075640613 @default.
• W4205698172 hasAuthorship W4205698172A5076055248 @default.
• W4205698172 hasAuthorship W4205698172A5078542383 @default.
• W4205698172 hasAuthorship W4205698172A5081659034 @default.
• W4205698172 hasAuthorship W4205698172A5082198148 @default.
• W4205698172 hasAuthorship W4205698172A5083966256 @default.
• W4205698172 hasAuthorship W4205698172A5085160808 @default.
• W4205698172 hasAuthorship W4205698172A5085832913 @default.
• W4205698172 hasAuthorship W4205698172A5090364896 @default.
• W4205698172 hasBestOaLocation W42056981721 @default.
• W4205698172 hasConcept C118552586 @default.
• W4205698172 hasConcept C138496976 @default.
• W4205698172 hasConcept C142853389 @default.
• W4205698172 hasConcept C15744967 @default.
• W4205698172 hasConcept C169760540 @default.
• W4205698172 hasConcept C169900460 @default.
• W4205698172 hasConcept C177264268 @default.
• W4205698172 hasConcept C180747234 @default.
• W4205698172 hasConcept C199360897 @default.
• W4205698172 hasConcept C2776895053 @default.
• W4205698172 hasConcept C2777056318 @default.
• W4205698172 hasConcept C2780313146 @default.
• W4205698172 hasConcept C2781195155 @default.
• W4205698172 hasConcept C41008148 @default.
• W4205698172 hasConcept C542102704 @default.
• W4205698172 hasConcept C58693492 @default.
• W4205698172 hasConceptScore W4205698172C118552586 @default.
• W4205698172 hasConceptScore W4205698172C138496976 @default.
• W4205698172 hasConceptScore W4205698172C142853389 @default.
• W4205698172 hasConceptScore W4205698172C15744967 @default.
• W4205698172 hasConceptScore W4205698172C169760540 @default.
• W4205698172 hasConceptScore W4205698172C169900460 @default.
• W4205698172 hasConceptScore W4205698172C177264268 @default.

• next