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- W4205827557 abstract "This chapter discusses drugs used in ocular treatment. The introduction of timolol maleate as a potent non-cardioselectire beta-blocker has a significant ocular hypotensive effect in animals and man. Absence of miosis, accommodative spasm and blurred vision, which are characteristic of therapy with pilocarpine or other miotics, are considered to represent a major advantage with timolol therapy. In addition to the miotics, other currently available drugs for the treatment of glaucoma, including the adrenergic agents and carbonic anhydrase inhibitors, often present problems with troublesome side effects which may limit their effectiveness. The availability of a well tolerated and effective antiglaucomatous agent such as timolol would appear to fill an important need manifest in the current state of glaucoma therapy. Timolol is studied primarily in comparative trials against adrenaline or pilocarpine in patients with open-angle glaucoma. Imolol is studied primarily in comparative trials against adrenaline or pilocarpine in patients with open-angle glaucoma. Timolol was slightly more effective than pilocarpine in lowering intraocular pressure (lOP) and was significantly more effective than adrenaline." @default.
- W4205827557 created "2022-01-25" @default.
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- W4205827557 date "1981-01-01" @default.
- W4205827557 modified "2023-09-29" @default.
- W4205827557 title "Drugs used in ocular treatment" @default.
- W4205827557 doi "https://doi.org/10.1016/s0378-6080(81)80053-0" @default.
- W4205827557 hasPublicationYear "1981" @default.
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