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• W4206014749 endingPage "2798" @default.
• W4206014749 startingPage "2785" @default.
• W4206014749 abstract "Sphingolipids are essential metabolites found in all plant species. They are required for plasma membrane integrity, tolerance of and responses to biotic and abiotic stresses, and intracellular signalling. There is extensive diversity in the sphingolipid content of different plant species, and in the identities and roles of enzymes required for their processing. In this review, we survey results obtained from investigations of the classical genetic model Arabidopsis thaliana, from assorted dicots with less extensive genetic toolkits, from the model monocot Oryza sativa, and finally from the model bryophyte Physcomitrium patens. For each species or group, we first broadly summarize what is known about sphingolipid content. We then discuss the most insightful and puzzling features of modifications to the hydrophobic ceramides, and to the polar headgroups of complex sphingolipids. Altogether, this data can serve as a framework for our knowledge of sphingolipid metabolism across the plant kingdom. This chemical and metabolic heterogeneity underpins equally diverse functions. With greater availability of different tools for analytical measurements and genetic manipulation, our field is entering an exciting phase of expanding our knowledge of the biological functions of this persistently cryptic class of lipids." @default.
• W4206014749 created "2022-01-26" @default.
• W4206014749 creator A5014546503 @default.
• W4206014749 creator A5015182241 @default.
• W4206014749 date "2022-02-03" @default.
• W4206014749 modified "2023-10-13" @default.
• W4206014749 title "Diversity in sphingolipid metabolism across land plants" @default.
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