FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4206023729> ?p ?o ?g. }

• W4206023729 endingPage "374" @default.
• W4206023729 startingPage "360" @default.
• W4206023729 abstract "This study aimed to investigate the highly differentiated urothelial apical surface glycome. The functions of the mammalian urothelium, lining the majority of the urinary tract and providing a barrier against toxins in urine, are dependent on the correct differentiation of urothelial cells, relying on protein expression, modification, and complex assembly to regulate the formation of multiple differentiated cell layers. Protein glycosylation, a poorly studied aspect of urothelial differentiation, contributes to the apical glycome and is implicated in the development of urothelial diseases. To enable surface glycome characterization, we developed a method to collect tissue apical surface N- and O-glycans. A simple, novel device using basic laboratory supplies was developed for enzymatic shaving of the luminal bladder urothelial surface, with subsequent release and mass spectrometric analysis of apical surface O- and N-glycans, the first normal mammalian urothelial N-glycome to be defined. Trypsinization of superficial glycoproteins was tracked using immunolabeling of the apically expressed uroplakin 3a protein to optimize enzymatic release, without compromising the integrity of the superficial urothelial layer. The approach developed for releasing apical tissue surface glycans allowed for comparison with the N-glycome of the total porcine bladder urothelial cells and thus identification of apical surface glycans as candidates implicated in the urothelial barrier function. Data are available in MassIve: MSV000087851." @default.
• W4206023729 created "2022-01-26" @default.
• W4206023729 creator A5001635562 @default.
• W4206023729 creator A5025375470 @default.
• W4206023729 creator A5039674139 @default.
• W4206023729 creator A5042773454 @default.
• W4206023729 date "2022-01-05" @default.
• W4206023729 modified "2023-10-16" @default.
• W4206023729 title "Surface Shave: Revealing the Apical-Restricted Uroglycome" @default.
• W4206023729 cites W1502708974 @default.
• W4206023729 cites W1602509013 @default.
• W4206023729 cites W1604557362 @default.
• W4206023729 cites W1814977477 @default.
• W4206023729 cites W1911301755 @default.
• W4206023729 cites W1968014420 @default.
• W4206023729 cites W1969724065 @default.
• W4206023729 cites W1972431666 @default.
• W4206023729 cites W1975945974 @default.
• W4206023729 cites W1976484683 @default.
• W4206023729 cites W1994441900 @default.
• W4206023729 cites W1995025776 @default.
• W4206023729 cites W1997638752 @default.
• W4206023729 cites W2005127348 @default.
• W4206023729 cites W2007231084 @default.
• W4206023729 cites W2009455582 @default.
• W4206023729 cites W2015044048 @default.
• W4206023729 cites W2017614094 @default.
• W4206023729 cites W2022375467 @default.
• W4206023729 cites W2024937427 @default.
• W4206023729 cites W2027986696 @default.
• W4206023729 cites W2039835691 @default.
• W4206023729 cites W2053478651 @default.
• W4206023729 cites W2057007315 @default.
• W4206023729 cites W2057887191 @default.
• W4206023729 cites W2064961433 @default.
• W4206023729 cites W2071031876 @default.
• W4206023729 cites W2073544824 @default.
• W4206023729 cites W2079028138 @default.
• W4206023729 cites W2083954684 @default.
• W4206023729 cites W2087285822 @default.
• W4206023729 cites W2095581779 @default.
• W4206023729 cites W2101057162 @default.
• W4206023729 cites W2102178595 @default.
• W4206023729 cites W2114538173 @default.
• W4206023729 cites W2116272367 @default.
• W4206023729 cites W2125345337 @default.
• W4206023729 cites W2133274933 @default.
• W4206023729 cites W2135567092 @default.
• W4206023729 cites W2135841958 @default.
• W4206023729 cites W2139700389 @default.
• W4206023729 cites W2147217003 @default.
• W4206023729 cites W2150547580 @default.
• W4206023729 cites W2161441815 @default.
• W4206023729 cites W2163387042 @default.
• W4206023729 cites W2163928870 @default.
• W4206023729 cites W2164497783 @default.
• W4206023729 cites W2325402346 @default.
• W4206023729 cites W2332400813 @default.
• W4206023729 cites W2547586367 @default.
• W4206023729 cites W2597775464 @default.
• W4206023729 cites W2609913648 @default.
• W4206023729 cites W2941449740 @default.
• W4206023729 cites W2976477804 @default.
• W4206023729 doi "https://doi.org/10.1021/acs.jproteome.1c00714" @default.
• W4206023729 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34985888" @default.
• W4206023729 hasPublicationYear "2022" @default.
• W4206023729 type Work @default.
• W4206023729 citedByCount "1" @default.
• W4206023729 countsByYear W42060237292022 @default.
• W4206023729 crossrefType "journal-article" @default.
• W4206023729 hasAuthorship W4206023729A5001635562 @default.
• W4206023729 hasAuthorship W4206023729A5025375470 @default.
• W4206023729 hasAuthorship W4206023729A5039674139 @default.
• W4206023729 hasAuthorship W4206023729A5042773454 @default.
• W4206023729 hasBestOaLocation W42060237292 @default.
• W4206023729 hasConcept C105702510 @default.
• W4206023729 hasConcept C108625454 @default.
• W4206023729 hasConcept C153911025 @default.
• W4206023729 hasConcept C158650290 @default.
• W4206023729 hasConcept C185592680 @default.
• W4206023729 hasConcept C206212055 @default.
• W4206023729 hasConcept C2777313579 @default.
• W4206023729 hasConcept C2777540882 @default.
• W4206023729 hasConcept C2910041100 @default.
• W4206023729 hasConcept C55493867 @default.
• W4206023729 hasConcept C77411442 @default.
• W4206023729 hasConcept C86803240 @default.
• W4206023729 hasConcept C95444343 @default.
• W4206023729 hasConceptScore W4206023729C105702510 @default.
• W4206023729 hasConceptScore W4206023729C108625454 @default.
• W4206023729 hasConceptScore W4206023729C153911025 @default.
• W4206023729 hasConceptScore W4206023729C158650290 @default.
• W4206023729 hasConceptScore W4206023729C185592680 @default.
• W4206023729 hasConceptScore W4206023729C206212055 @default.
• W4206023729 hasConceptScore W4206023729C2777313579 @default.
• W4206023729 hasConceptScore W4206023729C2777540882 @default.
• W4206023729 hasConceptScore W4206023729C2910041100 @default.
• W4206023729 hasConceptScore W4206023729C55493867 @default.

• next