FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4206064897> ?p ?o ?g. }

• W4206064897 endingPage "4446" @default.
• W4206064897 startingPage "4446" @default.
• W4206064897 abstract "Aim . To assess the relationship of various clinical and biological markers of bone metabolism with the progression of coronary artery calcification (CAC) in patients with stable coronary artery disease (CAD) within 5 years after coronary artery bypass grafting (CABG). Material and methods . This single-center prospective observational study included 111 men with CAD who were hospitalized for elective CABG. In the preoperative period, all patients underwent duplex ultrasound of extracranial arteries (ECA) and multislice computed tomography (MSCT) to assess CAC severity using the Agatston score, as well as densitometry with determination of bone mineral density in the femoral neck, lumbar spine and T-score for them, In all participants, the following bone metabolism biomarkers were studied: calcium, phosphorus, calcitonin, osteopontin, osteocalcin, osteoprotegerin (OPG), alkaline phosphatase, parathyroid hormone. Five years after CABG, ECA duplex ultrasound, MSCT coronary angiography and bone metabolism tests were repeated. Depending on CAC progression (>100 Agatston units (AU)), patients were divided into two groups to identify significant biomarkers and clinical risk factors associated with CAC progression. Results . For 5 years after CABG, contact with 16 (14,4%) patients was not possible; however, their vital status was assessed (they were alive). Death was recorded in 4 (3,6%) cases (3 — due to myocardial infarction, 1 — due to stroke). In 18 (19,7%) cases, non-fatal endpoints were revealed: angina recurrence after CABG — 16 patients, myocardial infarction — 1 patient, emergency stenting for unstable angina — 1 patient. There were no differences in the incidence of events between the groups with and without CAC progression. According to MSCT 5 years after CABG (n=91 (81,9%)), CAC progression was detected in 60 (65,9%) patients. Multivariate analysis allowed to create a model for predicting the risk of CAC progression, which included following parameters: cathepsin K <16,75 pmol/L (p=0,003) and bone mineral density <0,95 g/cm3 according to femoral neck densitometry before CABG (p=0,016); OPG <3,58 pg/ml (p=0,016) in the postoperative period 5 years after CABG. Conclusion . Within 5 years after CABG, 65,9% of male patients with stable coronary artery disease have CAC progression, the main predictors of which are low preoperative cathepsin K level (<16,75 pmol/L) and low bone mineral density (<0,95 g/cm3) according to femoral neck densitometry, as well as a low OPG level (<3,58 pg/ml) 5 years after CABG." @default.
• W4206064897 created "2022-01-25" @default.
• W4206064897 creator A5002913014 @default.
• W4206064897 creator A5004837596 @default.
• W4206064897 creator A5012411769 @default.
• W4206064897 creator A5021441161 @default.
• W4206064897 creator A5022158245 @default.
• W4206064897 creator A5075770366 @default.
• W4206064897 date "2021-06-20" @default.
• W4206064897 modified "2023-10-06" @default.
• W4206064897 title "Clinical and biochemical markers of coronary artery calcification progression after elective coronary artery bypass grafting" @default.
• W4206064897 cites W1520509761 @default.
• W4206064897 cites W1924481108 @default.
• W4206064897 cites W1975016287 @default.
• W4206064897 cites W2103506323 @default.
• W4206064897 cites W2200002157 @default.
• W4206064897 cites W2289712014 @default.
• W4206064897 cites W2292256093 @default.
• W4206064897 cites W2417517869 @default.
• W4206064897 cites W2472784575 @default.
• W4206064897 cites W2538223731 @default.
• W4206064897 cites W2598815521 @default.
• W4206064897 cites W2599722395 @default.
• W4206064897 cites W2647171660 @default.
• W4206064897 cites W2729372018 @default.
• W4206064897 cites W2736032499 @default.
• W4206064897 cites W2745609271 @default.
• W4206064897 cites W2746047252 @default.
• W4206064897 cites W2799630245 @default.
• W4206064897 cites W2871759739 @default.
• W4206064897 cites W2888250437 @default.
• W4206064897 cites W2901131520 @default.
• W4206064897 cites W2936520441 @default.
• W4206064897 cites W2944625101 @default.
• W4206064897 cites W2945567203 @default.
• W4206064897 cites W2965027208 @default.
• W4206064897 cites W2966070586 @default.
• W4206064897 cites W2979484668 @default.
• W4206064897 cites W2999187919 @default.
• W4206064897 cites W3010959373 @default.
• W4206064897 cites W3012332893 @default.
• W4206064897 cites W3033131456 @default.
• W4206064897 cites W3045922636 @default.
• W4206064897 cites W2605686978 @default.
• W4206064897 doi "https://doi.org/10.15829/1560-4071-2021-4446" @default.
• W4206064897 hasPublicationYear "2021" @default.
• W4206064897 type Work @default.
• W4206064897 citedByCount "0" @default.
• W4206064897 crossrefType "journal-article" @default.
• W4206064897 hasAuthorship W4206064897A5002913014 @default.
• W4206064897 hasAuthorship W4206064897A5004837596 @default.
• W4206064897 hasAuthorship W4206064897A5012411769 @default.
• W4206064897 hasAuthorship W4206064897A5021441161 @default.
• W4206064897 hasAuthorship W4206064897A5022158245 @default.
• W4206064897 hasAuthorship W4206064897A5075770366 @default.
• W4206064897 hasBestOaLocation W42060648971 @default.
• W4206064897 hasConcept C126322002 @default.
• W4206064897 hasConcept C131075544 @default.
• W4206064897 hasConcept C160160445 @default.
• W4206064897 hasConcept C164705383 @default.
• W4206064897 hasConcept C170033053 @default.
• W4206064897 hasConcept C181199279 @default.
• W4206064897 hasConcept C185592680 @default.
• W4206064897 hasConcept C2776820930 @default.
• W4206064897 hasConcept C2777910003 @default.
• W4206064897 hasConcept C2778213512 @default.
• W4206064897 hasConcept C2778425758 @default.
• W4206064897 hasConcept C500558357 @default.
• W4206064897 hasConcept C55493867 @default.
• W4206064897 hasConcept C71924100 @default.
• W4206064897 hasConceptScore W4206064897C126322002 @default.
• W4206064897 hasConceptScore W4206064897C131075544 @default.
• W4206064897 hasConceptScore W4206064897C160160445 @default.
• W4206064897 hasConceptScore W4206064897C164705383 @default.
• W4206064897 hasConceptScore W4206064897C170033053 @default.
• W4206064897 hasConceptScore W4206064897C181199279 @default.
• W4206064897 hasConceptScore W4206064897C185592680 @default.
• W4206064897 hasConceptScore W4206064897C2776820930 @default.
• W4206064897 hasConceptScore W4206064897C2777910003 @default.
• W4206064897 hasConceptScore W4206064897C2778213512 @default.
• W4206064897 hasConceptScore W4206064897C2778425758 @default.
• W4206064897 hasConceptScore W4206064897C500558357 @default.
• W4206064897 hasConceptScore W4206064897C55493867 @default.
• W4206064897 hasConceptScore W4206064897C71924100 @default.
• W4206064897 hasIssue "12" @default.
• W4206064897 hasLocation W42060648971 @default.
• W4206064897 hasLocation W42060648972 @default.
• W4206064897 hasOpenAccess W4206064897 @default.
• W4206064897 hasPrimaryLocation W42060648971 @default.
• W4206064897 hasRelatedWork W1971345608 @default.
• W4206064897 hasRelatedWork W1977729419 @default.
• W4206064897 hasRelatedWork W1983569838 @default.
• W4206064897 hasRelatedWork W2030354228 @default.
• W4206064897 hasRelatedWork W2041938128 @default.
• W4206064897 hasRelatedWork W2135975603 @default.
• W4206064897 hasRelatedWork W2356860550 @default.
• W4206064897 hasRelatedWork W2410354677 @default.
• W4206064897 hasRelatedWork W2417414779 @default.

• next