Matches in SemOpenAlex for { <https://semopenalex.org/work/W4206070644> ?p ?o ?g. }
- W4206070644 endingPage "1385" @default.
- W4206070644 startingPage "1378" @default.
- W4206070644 abstract "Metal-organic frameworks (MOFs) are promising multifunctional porous materials for biomedical and environmental applications. Here, we report synthesis and characterization of a new MOF based on the tetrahedral secondary building unit [Zn4O(CBAB)3]n (NUIG4), where CBABH2 = 4-((4-carboxybenzylidene)amino)benzoic acid. NUIG4 belongs to the family of MOFs with primitive cubic pcu topology, being a rare example with 4-fold interpenetration. The pore architecture enables unprecedentedly high doxorubicin (DOX) loading capacity (1955 mg DOX/g NUIG4) with pH-controlled release. Solid-state NMR and ab initio modeling confirmed formation of aromatic π-π stacking interactions between DOX and the framework. Preliminary cell-line experiments suggested a protective effect of NUIG4 on healthy HDF cells against DOX toxicity. NUIG4 also displays potential for adsorptive small-molecule gas separation, with a BET surface area of 1358 m2 g-1 and high selectivity of 2.75 for C2H2 over CO2." @default.
- W4206070644 created "2022-01-25" @default.
- W4206070644 creator A5000533517 @default.
- W4206070644 creator A5009958186 @default.
- W4206070644 creator A5019632748 @default.
- W4206070644 creator A5020986486 @default.
- W4206070644 creator A5022233884 @default.
- W4206070644 creator A5035438001 @default.
- W4206070644 creator A5036001346 @default.
- W4206070644 creator A5036756564 @default.
- W4206070644 creator A5040708976 @default.
- W4206070644 creator A5047829258 @default.
- W4206070644 creator A5051321060 @default.
- W4206070644 creator A5052316636 @default.
- W4206070644 creator A5058048911 @default.
- W4206070644 creator A5059589835 @default.
- W4206070644 creator A5064278171 @default.
- W4206070644 creator A5069669531 @default.
- W4206070644 date "2022-01-01" @default.
- W4206070644 modified "2023-10-16" @default.
- W4206070644 title "NUIG4: A biocompatible pcu metal–organic framework with an exceptional doxorubicin encapsulation capacity" @default.
- W4206070644 cites W1767102537 @default.
- W4206070644 cites W1778497012 @default.
- W4206070644 cites W1953531402 @default.
- W4206070644 cites W1974688804 @default.
- W4206070644 cites W1975501285 @default.
- W4206070644 cites W1989195046 @default.
- W4206070644 cites W1998358059 @default.
- W4206070644 cites W2001059668 @default.
- W4206070644 cites W2002449355 @default.
- W4206070644 cites W2004550299 @default.
- W4206070644 cites W2008151531 @default.
- W4206070644 cites W2013470095 @default.
- W4206070644 cites W2021635812 @default.
- W4206070644 cites W2022085591 @default.
- W4206070644 cites W2028056984 @default.
- W4206070644 cites W2029785169 @default.
- W4206070644 cites W2032687183 @default.
- W4206070644 cites W2034316482 @default.
- W4206070644 cites W2045381262 @default.
- W4206070644 cites W2050343674 @default.
- W4206070644 cites W2051708290 @default.
- W4206070644 cites W2051808592 @default.
- W4206070644 cites W2055928148 @default.
- W4206070644 cites W2059301415 @default.
- W4206070644 cites W2065355693 @default.
- W4206070644 cites W2066784675 @default.
- W4206070644 cites W2066991705 @default.
- W4206070644 cites W2070132142 @default.
- W4206070644 cites W2070986221 @default.
- W4206070644 cites W2077431908 @default.
- W4206070644 cites W2082179062 @default.
- W4206070644 cites W2083555382 @default.
- W4206070644 cites W2085675301 @default.
- W4206070644 cites W2090904233 @default.
- W4206070644 cites W2091161882 @default.
- W4206070644 cites W2094774149 @default.
- W4206070644 cites W2096988215 @default.
- W4206070644 cites W2102307463 @default.
- W4206070644 cites W2102897174 @default.
- W4206070644 cites W2104354032 @default.
- W4206070644 cites W2105631122 @default.
- W4206070644 cites W2111423624 @default.
- W4206070644 cites W2112017750 @default.
- W4206070644 cites W2112307556 @default.
- W4206070644 cites W2122909722 @default.
- W4206070644 cites W2127051096 @default.
- W4206070644 cites W2129559321 @default.
- W4206070644 cites W2131988676 @default.
- W4206070644 cites W2132667015 @default.
- W4206070644 cites W2140182328 @default.
- W4206070644 cites W2141939342 @default.
- W4206070644 cites W2146969170 @default.
- W4206070644 cites W2164043498 @default.
- W4206070644 cites W2166173762 @default.
- W4206070644 cites W2185376522 @default.
- W4206070644 cites W2264512873 @default.
- W4206070644 cites W2279533943 @default.
- W4206070644 cites W2294085143 @default.
- W4206070644 cites W2320312730 @default.
- W4206070644 cites W2328455351 @default.
- W4206070644 cites W2328906361 @default.
- W4206070644 cites W2330907473 @default.
- W4206070644 cites W2343128346 @default.
- W4206070644 cites W2462182227 @default.
- W4206070644 cites W2554773181 @default.
- W4206070644 cites W2590362922 @default.
- W4206070644 cites W2771155547 @default.
- W4206070644 cites W2790308498 @default.
- W4206070644 cites W2793488593 @default.
- W4206070644 cites W2890167612 @default.
- W4206070644 cites W2898522442 @default.
- W4206070644 cites W2900960361 @default.
- W4206070644 cites W2904802009 @default.
- W4206070644 cites W292851245 @default.
- W4206070644 cites W2932410572 @default.
- W4206070644 cites W2967157862 @default.
- W4206070644 cites W2972221648 @default.