FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4206101723> ?p ?o ?g. }

• W4206101723 endingPage "10" @default.
• W4206101723 startingPage "1" @default.
• W4206101723 abstract "Hepatocellular carcinoma (HCC) remains a devastating tumor globally. Serum exosomes are reliable biomarkers for tumors, including HCC. Hence, this study explored the efficacy and mechanism of serum exosomes in HCC.microRNA (miR)-122 and miR-148a expressions in serum exosomes from HCC patients and healthy subjects and their predictive efficacy for HCC were detected. Correlation between serum exosomal miR-122/148a expressions with survival rate, clinical stage, lymph node metastasis, and tumor differentiation level and levels of HCC-related serum markers (CA199, FucAFP, ALD-A, and AFu) were detected. PAX2 staining intensity and expression in HCC were measured. PAX2 predictive efficacy for HCC and its correlation with clinical stage, lymph node metastasis, tumor differentiation level, and HCC-related serum marker levels were analyzed. The targeted binding relationship between miR-122 and miR-148a and PAX2 was predicted and verified.Serum exosomal miR-122 and miR-148a expressions were downregulated in HCC, showing potent predictive efficacy for HCC, which was negatively related to clinical stage and lymph node metastasis and positively related to tumor differentiation level, patient survival rate, and HCC-related serum marker levels. PAX2 showed increased staining intensity and expression in HCC, together with high predictive efficacy for HCC. PAX2 expression showed a positive correlation with clinical stage and lymph node metastasis and a negative correlation with tumor differentiation level and HCC-related serum marker levels. miR-122 and miR-148a conjointly targeted PAX2 in HCC.We demonstrated that serum exosomal miR-122 and miR-148a played a predictive role and were linked to prognosis in HCC via interactions with PAX2." @default.
• W4206101723 created "2022-01-25" @default.
• W4206101723 creator A5017004955 @default.
• W4206101723 creator A5071329903 @default.
• W4206101723 creator A5085290375 @default.
• W4206101723 date "2022-01-04" @default.
• W4206101723 modified "2023-09-26" @default.
• W4206101723 title "The Predictive Efficacy of Serum Exosomal microRNA-122 and microRNA-148a for Hepatocellular Carcinoma Based on Smart Healthcare" @default.
• W4206101723 cites W1500925570 @default.
• W4206101723 cites W2010927970 @default.
• W4206101723 cites W2030895526 @default.
• W4206101723 cites W2033857297 @default.
• W4206101723 cites W2042910438 @default.
• W4206101723 cites W2050442471 @default.
• W4206101723 cites W2160814840 @default.
• W4206101723 cites W2213848118 @default.
• W4206101723 cites W2307254256 @default.
• W4206101723 cites W2524497122 @default.
• W4206101723 cites W2618422746 @default.
• W4206101723 cites W2751453676 @default.
• W4206101723 cites W2752045530 @default.
• W4206101723 cites W2761079023 @default.
• W4206101723 cites W2769100372 @default.
• W4206101723 cites W2770355315 @default.
• W4206101723 cites W2783944216 @default.
• W4206101723 cites W2790368470 @default.
• W4206101723 cites W2894766454 @default.
• W4206101723 cites W2899463308 @default.
• W4206101723 cites W2900597665 @default.
• W4206101723 cites W2907978256 @default.
• W4206101723 cites W2910316245 @default.
• W4206101723 cites W2911643782 @default.
• W4206101723 cites W2921766690 @default.
• W4206101723 cites W2927467816 @default.
• W4206101723 cites W2949512677 @default.
• W4206101723 cites W2955059868 @default.
• W4206101723 cites W2968395394 @default.
• W4206101723 cites W2971827065 @default.
• W4206101723 cites W2976977668 @default.
• W4206101723 cites W2983682411 @default.
• W4206101723 cites W3015933549 @default.
• W4206101723 cites W3032719025 @default.
• W4206101723 cites W4247544731 @default.
• W4206101723 doi "https://doi.org/10.1155/2022/5914541" @default.
• W4206101723 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35028121" @default.
• W4206101723 hasPublicationYear "2022" @default.
• W4206101723 type Work @default.
• W4206101723 citedByCount "6" @default.
• W4206101723 countsByYear W42061017232022 @default.
• W4206101723 countsByYear W42061017232023 @default.
• W4206101723 crossrefType "journal-article" @default.
• W4206101723 hasAuthorship W4206101723A5017004955 @default.
• W4206101723 hasAuthorship W4206101723A5071329903 @default.
• W4206101723 hasAuthorship W4206101723A5085290375 @default.
• W4206101723 hasBestOaLocation W42061017231 @default.
• W4206101723 hasConcept C104317684 @default.
• W4206101723 hasConcept C121608353 @default.
• W4206101723 hasConcept C126322002 @default.
• W4206101723 hasConcept C142724271 @default.
• W4206101723 hasConcept C143998085 @default.
• W4206101723 hasConcept C145059251 @default.
• W4206101723 hasConcept C146357865 @default.
• W4206101723 hasConcept C151730666 @default.
• W4206101723 hasConcept C20518536 @default.
• W4206101723 hasConcept C2778019345 @default.
• W4206101723 hasConcept C2779013556 @default.
• W4206101723 hasConcept C2780521871 @default.
• W4206101723 hasConcept C2780849966 @default.
• W4206101723 hasConcept C2781197716 @default.
• W4206101723 hasConcept C502942594 @default.
• W4206101723 hasConcept C55493867 @default.
• W4206101723 hasConcept C71924100 @default.
• W4206101723 hasConcept C86803240 @default.
• W4206101723 hasConceptScore W4206101723C104317684 @default.
• W4206101723 hasConceptScore W4206101723C121608353 @default.
• W4206101723 hasConceptScore W4206101723C126322002 @default.
• W4206101723 hasConceptScore W4206101723C142724271 @default.
• W4206101723 hasConceptScore W4206101723C143998085 @default.
• W4206101723 hasConceptScore W4206101723C145059251 @default.
• W4206101723 hasConceptScore W4206101723C146357865 @default.
• W4206101723 hasConceptScore W4206101723C151730666 @default.
• W4206101723 hasConceptScore W4206101723C20518536 @default.
• W4206101723 hasConceptScore W4206101723C2778019345 @default.
• W4206101723 hasConceptScore W4206101723C2779013556 @default.
• W4206101723 hasConceptScore W4206101723C2780521871 @default.
• W4206101723 hasConceptScore W4206101723C2780849966 @default.
• W4206101723 hasConceptScore W4206101723C2781197716 @default.
• W4206101723 hasConceptScore W4206101723C502942594 @default.
• W4206101723 hasConceptScore W4206101723C55493867 @default.
• W4206101723 hasConceptScore W4206101723C71924100 @default.
• W4206101723 hasConceptScore W4206101723C86803240 @default.
• W4206101723 hasLocation W42061017231 @default.
• W4206101723 hasLocation W42061017232 @default.
• W4206101723 hasLocation W42061017233 @default.
• W4206101723 hasLocation W42061017234 @default.
• W4206101723 hasOpenAccess W4206101723 @default.
• W4206101723 hasPrimaryLocation W42061017231 @default.
• W4206101723 hasRelatedWork W2042559265 @default.

• next