FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4206165714> ?p ?o ?g. }

• W4206165714 abstract "Melatonin is an antioxidant with anti-inflammatory and anti-apoptotic effects. Animal studies have supported a fetal neuroprotective role for melatonin when administered maternally. It is important to assess whether melatonin, given to the mother, can reduce the risk of neurosensory disabilities (including cerebral palsy) and death, associated with fetal brain injury, for the preterm or term compromised fetus.To assess the effects of melatonin when used for neuroprotection of the fetus.We searched the Cochrane Pregnancy and Childbirth Group's Trials Register (31 January 2016).We planned to include randomised controlled trials and quasi-randomised controlled trials comparing melatonin given to women in pregnancy (regardless of the route, timing, dose and duration of administration) for fetal neuroprotection with placebo, no treatment, or with an alternative agent aimed at providing fetal neuroprotection. We also planned to include comparisons of different regimens for administration of melatonin.Two review authors planned to independently assess trial eligibility, trial quality and extract the data.We found no randomised trials for inclusion in this review. One study is ongoing.As we did not identify any randomised trials for inclusion in this review, we are unable to comment on implications for practice at this stage.Although evidence from animals studies has supported a fetal neuroprotective role for melatonin when administered to the mother during pregnancy, no trials assessing melatonin for fetal neuroprotection in pregnant women have been completed to date. However, there is currently one ongoing randomised controlled trial (with an estimated enrolment target of 60 pregnant women) which examines the dose of melatonin, administered to women at risk of imminent very preterm birth (less than 28 weeks' gestation) required to reduce brain damage in the white matter of the babies that were born very preterm.Further high-quality research is needed and research efforts should directed towards trials comparing melatonin with either no intervention (no treatment or placebo), or with alternative agents aimed at providing fetal neuroprotection (such as magnesium sulphate for the very preterm infant). Such trials should evaluate maternal and infant short- and longer-term outcomes (including neurosensory disabilities such as cerebral palsy), and consider the costs of care." @default.
• W4206165714 created "2022-01-25" @default.
• W4206165714 creator A5008343091 @default.
• W4206165714 creator A5037782277 @default.
• W4206165714 creator A5089091400 @default.
• W4206165714 date "2016-03-29" @default.
• W4206165714 modified "2023-09-25" @default.
• W4206165714 title "Melatonin for women in pregnancy for neuroprotection of the fetus" @default.
• W4206165714 cites W1485887944 @default.
• W4206165714 cites W1497798804 @default.
• W4206165714 cites W1892729147 @default.
• W4206165714 cites W1966357480 @default.
• W4206165714 cites W1972185079 @default.
• W4206165714 cites W1973993738 @default.
• W4206165714 cites W1976812106 @default.
• W4206165714 cites W1979265652 @default.
• W4206165714 cites W1981636067 @default.
• W4206165714 cites W1981934276 @default.
• W4206165714 cites W1982099506 @default.
• W4206165714 cites W2003692629 @default.
• W4206165714 cites W2006761570 @default.
• W4206165714 cites W2006868283 @default.
• W4206165714 cites W2010323936 @default.
• W4206165714 cites W2012488528 @default.
• W4206165714 cites W2017548509 @default.
• W4206165714 cites W2021084656 @default.
• W4206165714 cites W2029459733 @default.
• W4206165714 cites W2031019500 @default.
• W4206165714 cites W2031898343 @default.
• W4206165714 cites W2032784868 @default.
• W4206165714 cites W2035961915 @default.
• W4206165714 cites W2042521527 @default.
• W4206165714 cites W2042810763 @default.
• W4206165714 cites W2053497190 @default.
• W4206165714 cites W2054714384 @default.
• W4206165714 cites W2057442927 @default.
• W4206165714 cites W2079639616 @default.
• W4206165714 cites W2082028502 @default.
• W4206165714 cites W2099048138 @default.
• W4206165714 cites W2099537524 @default.
• W4206165714 cites W2100881622 @default.
• W4206165714 cites W2108968902 @default.
• W4206165714 cites W2115218756 @default.
• W4206165714 cites W2120000441 @default.
• W4206165714 cites W2120967128 @default.
• W4206165714 cites W2138677837 @default.
• W4206165714 cites W2138924326 @default.
• W4206165714 cites W2142059781 @default.
• W4206165714 cites W2144648227 @default.
• W4206165714 cites W2149763277 @default.
• W4206165714 cites W2165670294 @default.
• W4206165714 cites W2170277233 @default.
• W4206165714 cites W68000199 @default.
• W4206165714 doi "https://doi.org/10.1002/14651858.cd010527.pub2" @default.
• W4206165714 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27022888" @default.
• W4206165714 hasPublicationYear "2016" @default.
• W4206165714 type Work @default.
• W4206165714 citedByCount "17" @default.
• W4206165714 countsByYear W42061657142017 @default.
• W4206165714 countsByYear W42061657142018 @default.
• W4206165714 countsByYear W42061657142019 @default.
• W4206165714 countsByYear W42061657142020 @default.
• W4206165714 countsByYear W42061657142021 @default.
• W4206165714 countsByYear W42061657142022 @default.
• W4206165714 crossrefType "journal-article" @default.
• W4206165714 hasAuthorship W4206165714A5008343091 @default.
• W4206165714 hasAuthorship W4206165714A5037782277 @default.
• W4206165714 hasAuthorship W4206165714A5089091400 @default.
• W4206165714 hasBestOaLocation W42061657142 @default.
• W4206165714 hasConcept C126322002 @default.
• W4206165714 hasConcept C131872663 @default.
• W4206165714 hasConcept C134018914 @default.
• W4206165714 hasConcept C172680121 @default.
• W4206165714 hasConcept C25498285 @default.
• W4206165714 hasConcept C2778182776 @default.
• W4206165714 hasConcept C2779234561 @default.
• W4206165714 hasConcept C54355233 @default.
• W4206165714 hasConcept C71924100 @default.
• W4206165714 hasConcept C86803240 @default.
• W4206165714 hasConceptScore W4206165714C126322002 @default.
• W4206165714 hasConceptScore W4206165714C131872663 @default.
• W4206165714 hasConceptScore W4206165714C134018914 @default.
• W4206165714 hasConceptScore W4206165714C172680121 @default.
• W4206165714 hasConceptScore W4206165714C25498285 @default.
• W4206165714 hasConceptScore W4206165714C2778182776 @default.
• W4206165714 hasConceptScore W4206165714C2779234561 @default.
• W4206165714 hasConceptScore W4206165714C54355233 @default.
• W4206165714 hasConceptScore W4206165714C71924100 @default.
• W4206165714 hasConceptScore W4206165714C86803240 @default.
• W4206165714 hasIssue "3" @default.
• W4206165714 hasLocation W42061657141 @default.
• W4206165714 hasLocation W42061657142 @default.
• W4206165714 hasLocation W42061657143 @default.
• W4206165714 hasOpenAccess W4206165714 @default.
• W4206165714 hasPrimaryLocation W42061657141 @default.
• W4206165714 hasRelatedWork W2056752164 @default.
• W4206165714 hasRelatedWork W2263403818 @default.
• W4206165714 hasRelatedWork W2359213711 @default.
• W4206165714 hasRelatedWork W2371606333 @default.
• W4206165714 hasRelatedWork W2386758381 @default.

• next