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- W4206167599 abstract "Cyclic nucleotide phosphodiesterase 9 (PDE9) is a member of the larger cyclic nucleotide phosphodiesterase superfamily of proteins. PDE9 hydrolyzes 3′-5′-cyclic-guanosine monophosphate (cyclic-GMP) to 5′-guanosine monophosphate (GMP), and has the highest substrate affinity (the Km for cyclic-GMP is approximately 70 nM) of all the PDEs. PDE9 appears to be widely expressed, with high levels of mRNA in kidney and brain." @default.
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- W4206167599 date "2007-01-01" @default.
- W4206167599 modified "2023-10-18" @default.
- W4206167599 title "Phosphodiesterase 9" @default.
- W4206167599 doi "https://doi.org/10.1016/b978-008055232-3.60550-1" @default.
- W4206167599 hasPublicationYear "2007" @default.
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