Matches in SemOpenAlex for { <https://semopenalex.org/work/W4206181330> ?p ?o ?g. }
- W4206181330 abstract "Therapeutic approaches that target the metabolism of tumor cells have been a popular research topic in recent years. Previous studies have demonstrated that glycolysis inhibitors reduce the proliferation of non‑small cell lung cancer (NSCLC) cells by interfering with the aerobic glycolytic pathway. However, the mitochondrial oxidative phosphorylation (OXPHOS) pathway in tumor cells has also been implicated in lung cancer metabolism. Metformin, a known inhibitor of mitochondrial OXPHOS, has been indicated to reduce NSCLC morbidity and mortality in clinical studies. The present article reviewed the therapeutic effects of metformin against NSCLC, both as a single agent and combined with other anticancer treatments, in order to provide a theoretical basis for its clinical use in adjuvant therapy for NSCLC." @default.
- W4206181330 created "2022-01-26" @default.
- W4206181330 creator A5029142865 @default.
- W4206181330 creator A5054803735 @default.
- W4206181330 creator A5082038664 @default.
- W4206181330 creator A5086528871 @default.
- W4206181330 date "2022-01-18" @default.
- W4206181330 modified "2023-10-05" @default.
- W4206181330 title "Advances in metformin‑based metabolic therapy for non‑small cell lung cancer (Review)" @default.
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