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- W4206202271 abstract "To investigate regional splanchnic and cerebral tissue oxygen saturation in preterm infants <30 weeks gestation.Cerebral (cTOI) and splanchnic (sTOI) Tissue Oxygenation Index were measured weekly in 5 min epochs for a total period of 60 min using NIRS (NIRO-300) for the first 8 weeks of life, in 48 appropriately grown preterm infants born at <30 weeks gestation. Infants who developed HPI and/or NEC (n = 12) and those that died (n = 1) were excluded from our main outcome measure of regional gut and cerebral tissue oxygenation in healthy preterm infants <30 weeks gestation.Median birthweight 789 g (460-1486), gestational age 25+6 weeks (23+0-29+1) and 51.4% female. 217 NIRS measurements were completed across the first 8 weeks of life. Mean weekly cTOI ranged from 56.8-65.4% and sTOI ranged from 36.7-46.0%. Mean cTOI was significantly higher than mean sTOI (p < 0.001) throughout the first 8 weeks of life. Mean cTOI decreased significantly with increasing postnatal age [-0.59% each week (-1.26% to -0.07%) p = 0.04]. None of the examined confounding factors had a significant effect.This is the first report of regional cerebral and splanchnic tissue oxygen saturation ranges during the first 8 weeks of life for preterm infants born at <30 weeks gestation." @default.
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- W4206202271 date "2022-02-01" @default.
- W4206202271 modified "2023-10-08" @default.
- W4206202271 title "Regional cerebral and splanchnic tissue oxygen saturation in preterm infants – Longitudinal normative measurements" @default.
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- W4206202271 doi "https://doi.org/10.1016/j.earlhumdev.2022.105540" @default.
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