Matches in SemOpenAlex for { <https://semopenalex.org/work/W4206333143> ?p ?o ?g. }
Showing items 1 to 93 of
93
with 100 items per page.
- W4206333143 endingPage "1246" @default.
- W4206333143 startingPage "1232" @default.
- W4206333143 abstract "A mild and efficient protocol was developed for the synthesis of pyrazole and 2°-amine hybrid conjugates through an InCl3 Ugi four-component reaction followed by a base mediated secondary amine coupling reaction. MCRs have been used extensively in the field of combinatorial chemistry, which offers the synthesis of libraries of similar molecules in a parallel fashion. A small library of novel N-allyl-N-(1-(4-(aminomethyl) phenyl)-2-(tert-butylamino)-2-oxoethyl)-1,3-diphenyl-1H-pyrazole-4-carboxamide scaffold was designed and synthesized through a one-pot four-component Ugi reaction, the resulting Ugi product pyrazole derivative coupled with various secondary amines to prepare target pyrazole – amine conjugate molecules. The structures of synthesized conjugates confirmed by spectroscopic techniques (NMR, C, H, N analysis, and MS). The in vitro antimicrobial survey of these pyrazole-secondary amine conjugates was supported by DFT studies; thereby notifies the conjugates are promising antimicrobial agents and are comparable to the standard antimicrobial molecules such as ampicilin, griseofulvin, isoniazide and rifampicin." @default.
- W4206333143 created "2022-01-25" @default.
- W4206333143 creator A5034212801 @default.
- W4206333143 creator A5064002081 @default.
- W4206333143 creator A5083037902 @default.
- W4206333143 date "2022-01-17" @default.
- W4206333143 modified "2023-09-24" @default.
- W4206333143 title "Design & Synthesis of InCl<sub>3</sub> Catalyzed Novel Pyrazole Conjugates with 2<sup>°</sup>-Amines; Discover Their in Vitro Antimicrobial & DFT Studies" @default.
- W4206333143 cites W2002434514 @default.
- W4206333143 cites W2008230870 @default.
- W4206333143 cites W2014286678 @default.
- W4206333143 cites W2027824703 @default.
- W4206333143 cites W2040588269 @default.
- W4206333143 cites W2054684310 @default.
- W4206333143 cites W2063432569 @default.
- W4206333143 cites W2064756382 @default.
- W4206333143 cites W2083782467 @default.
- W4206333143 cites W2087312494 @default.
- W4206333143 cites W2090271558 @default.
- W4206333143 cites W2107605751 @default.
- W4206333143 cites W2111677437 @default.
- W4206333143 cites W2114809965 @default.
- W4206333143 cites W2123413819 @default.
- W4206333143 cites W2143817689 @default.
- W4206333143 cites W2172350422 @default.
- W4206333143 cites W2174705034 @default.
- W4206333143 cites W2178733708 @default.
- W4206333143 cites W2328315364 @default.
- W4206333143 cites W2396690678 @default.
- W4206333143 cites W2407040666 @default.
- W4206333143 cites W2529451539 @default.
- W4206333143 cites W2569293339 @default.
- W4206333143 cites W2621559940 @default.
- W4206333143 cites W2795945400 @default.
- W4206333143 cites W2913028556 @default.
- W4206333143 cites W2950430336 @default.
- W4206333143 cites W2953161455 @default.
- W4206333143 cites W2979381900 @default.
- W4206333143 cites W3016762617 @default.
- W4206333143 cites W3036922956 @default.
- W4206333143 cites W3198212636 @default.
- W4206333143 doi "https://doi.org/10.1080/10406638.2022.2026986" @default.
- W4206333143 hasPublicationYear "2022" @default.
- W4206333143 type Work @default.
- W4206333143 citedByCount "2" @default.
- W4206333143 countsByYear W42063331432022 @default.
- W4206333143 countsByYear W42063331432023 @default.
- W4206333143 crossrefType "journal-article" @default.
- W4206333143 hasAuthorship W4206333143A5034212801 @default.
- W4206333143 hasAuthorship W4206333143A5064002081 @default.
- W4206333143 hasAuthorship W4206333143A5083037902 @default.
- W4206333143 hasConcept C131779359 @default.
- W4206333143 hasConcept C134306372 @default.
- W4206333143 hasConcept C178790620 @default.
- W4206333143 hasConcept C185592680 @default.
- W4206333143 hasConcept C197336794 @default.
- W4206333143 hasConcept C21951064 @default.
- W4206333143 hasConcept C2777682936 @default.
- W4206333143 hasConcept C32909587 @default.
- W4206333143 hasConcept C33923547 @default.
- W4206333143 hasConcept C4937899 @default.
- W4206333143 hasConcept C71240020 @default.
- W4206333143 hasConceptScore W4206333143C131779359 @default.
- W4206333143 hasConceptScore W4206333143C134306372 @default.
- W4206333143 hasConceptScore W4206333143C178790620 @default.
- W4206333143 hasConceptScore W4206333143C185592680 @default.
- W4206333143 hasConceptScore W4206333143C197336794 @default.
- W4206333143 hasConceptScore W4206333143C21951064 @default.
- W4206333143 hasConceptScore W4206333143C2777682936 @default.
- W4206333143 hasConceptScore W4206333143C32909587 @default.
- W4206333143 hasConceptScore W4206333143C33923547 @default.
- W4206333143 hasConceptScore W4206333143C4937899 @default.
- W4206333143 hasConceptScore W4206333143C71240020 @default.
- W4206333143 hasIssue "2" @default.
- W4206333143 hasLocation W42063331431 @default.
- W4206333143 hasOpenAccess W4206333143 @default.
- W4206333143 hasPrimaryLocation W42063331431 @default.
- W4206333143 hasRelatedWork W1968229709 @default.
- W4206333143 hasRelatedWork W1993950092 @default.
- W4206333143 hasRelatedWork W2006418481 @default.
- W4206333143 hasRelatedWork W2286654970 @default.
- W4206333143 hasRelatedWork W2599957976 @default.
- W4206333143 hasRelatedWork W2731480559 @default.
- W4206333143 hasRelatedWork W2883060360 @default.
- W4206333143 hasRelatedWork W2953082221 @default.
- W4206333143 hasRelatedWork W4243090031 @default.
- W4206333143 hasRelatedWork W4280612819 @default.
- W4206333143 hasVolume "43" @default.
- W4206333143 isParatext "false" @default.
- W4206333143 isRetracted "false" @default.
- W4206333143 workType "article" @default.