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- W4206352786 abstract "We synthesized N,N′,N″,N‴-tetraalkylcyclam derivatives in which alkyl groups were ethyl, propyl, butyl, methoxyethyl, and ethoxyethyl. We attempted to label the compounds with 99mTc. The cyclams with methyl, ethyl, and propyl could be labelled. The labelled N,N′,N″,N‴-tetraalkylcyclam derivatives showed +1 charge. They excreted rapidly through the kidney in mice. The liver-uptake increased slightly as the lipophilicity increased. However, the myocardial uptake was low unlikely with the +1 charged myocardial imaging agents. Copyright © 2001 John Wiley & Sons, Ltd." @default.
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- W4206352786 date "2001-03-30" @default.
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- W4206352786 title "N,N′,N″,N‴‐tetraalkylcyclam derivatives: synthesis, 99mTc‐labelling and biological properties" @default.
- W4206352786 doi "https://doi.org/10.1002/jlcr.448.abs" @default.
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