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- W4206408460 endingPage "4" @default.
- W4206408460 startingPage "4" @default.
- W4206408460 abstract "Hox genes play key roles in axial patterning and regulating the regional identity of cells and tissues in a wide variety of animals from invertebrates to vertebrates. Nested domains of Hox expression generate a combinatorial code that provides a molecular framework for specifying the properties of tissues along the A-P axis. Hence, it is important to understand the regulatory mechanisms that coordinately control the precise patterns of the transcription of clustered Hox genes required for their roles in development. New insights are emerging about the dynamics and molecular mechanisms governing transcriptional regulation, and there is interest in understanding how these may play a role in contributing to the regulation of the expression of the clustered Hox genes. In this review, we summarize some of the recent findings, ideas and emerging mechanisms underlying the regulation of transcription in general and consider how they may be relevant to understanding the transcriptional regulation of Hox genes." @default.
- W4206408460 created "2022-01-26" @default.
- W4206408460 creator A5022732047 @default.
- W4206408460 creator A5071192069 @default.
- W4206408460 date "2022-01-10" @default.
- W4206408460 modified "2023-10-05" @default.
- W4206408460 title "Transcriptional Regulation and Implications for Controlling Hox Gene Expression" @default.
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