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- W4206510366 abstract "Abstract Purpose We aimed to evaluate the relationships between the severity of peripheral arterial disease (PAD) and immune-nutritional status, as quantified by the prognostic nutritional index (PNI), controlling nutritional status score (CONUT), and modified Glasgow prognostic score (mGPS). Methods and results One hundred forty-eight patients with severe lower extremity PAD diagnosed by angiography constituted the study population. All patients had at least one severe superficial femoral arterial disease (SFA). According to the presence of a chronic total occlusion in SFA (SFA CTO), the study population was divided into two groups. Patients with SFA CTO (n: 84) had a significantly lower PNI(43.4 ± 4.8 vs. 49.1 ± 4.7, p < 0.001), worse mGPS and CONUT scores than those without SFA CTO(n:64). A comparison of the three groups, those classified according to PNI tertiles (PNI ≥ 48, n:49; 43.8 < PNI < 48, n:49; PNI < 43.8, n: 50), revealed that a lower PNI was associated with the presence of a TASC C-D lesion in the femoropopliteal segment, SFA CTO, long lesion, and long CTO. Furthermore, PNI was found to be an independent predictor of SFA CTO in the logistic regression analysis. Diagnostic performance of PNI was better than mGPS and CONUT scores in ROC curve comparison. Conclusion This is the first study demonstrating the relationship between PNI and PAD severity. Our results and the prognostic value of PNI should be validated in a larger prospective cohort." @default.
- W4206510366 created "2022-01-25" @default.
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- W4206510366 date "2021-04-12" @default.
- W4206510366 modified "2023-09-26" @default.
- W4206510366 title "Diagnostic Impact of Immunonutritional Indices in Peripheral Arterial Disease Severity and Complexity" @default.
- W4206510366 doi "https://doi.org/10.21203/rs.3.rs-388423/v1" @default.
- W4206510366 hasPublicationYear "2021" @default.
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