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• W4206520393 endingPage "13" @default.
• W4206520393 startingPage "13" @default.
• W4206520393 abstract "Cardiac arrhythmia, or irregular heart rhythm, is associated with morbidity and mortality and is described as one of the most important future public health challenges. Therefore, developing new models of cardiac arrhythmia is critical for understanding disease mechanisms, determining genetic underpinnings, and developing new therapeutic strategies. In the last few decades, the zebrafish has emerged as an attractive model to reproduce in vivo human cardiac pathologies, including arrhythmias. Here, we highlight the contribution of zebrafish to the field and discuss the available cardiac arrhythmia models. Further, we outline techniques to assess potential heart rhythm defects in larval and adult zebrafish. As genetic tools in zebrafish continue to bloom, this model will be crucial for functional genomics studies and to develop personalized anti-arrhythmic therapies." @default.
• W4206520393 created "2022-01-25" @default.
• W4206520393 creator A5012088746 @default.
• W4206520393 creator A5026297001 @default.
• W4206520393 creator A5080941650 @default.
• W4206520393 creator A5087657333 @default.
• W4206520393 date "2022-01-05" @default.
• W4206520393 modified "2023-10-14" @default.
• W4206520393 title "Modeling Human Cardiac Arrhythmias: Insights from Zebrafish" @default.
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