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• W4206533230 abstract "Abstract Background Inflammatory adverse events following COVID-19 vaccination are being reported amidst the growing concerns regarding vaccine’s immunogenicity and safety, especially in patients with pre-existing inflammatory conditions. Methods Multinational case series of patients diagnosed with an ocular inflammatory event within 14 days following COVID-19 vaccination collected from 40 centres over a 3 month period in 2021. Results Seventy patients presented with ocular inflammatory events within 14 days following COVID-19 vaccination. The mean age was 51 years (range, 19–84 years). The most common events were anterior uveitis ( n = 41, 58.6%), followed by posterior uveitis ( n = 9, 12.9%) and scleritis ( n = 7, 10.0%). The mean time to event was 5 days and 6 days (range, 1–14 days) after the first and second dose of vaccine, respectively. Among all patients, 36 (54.1%) had a previous history of ocular inflammatory event. Most patients ( n = 48, 68.6%) were managed with topical corticosteroids. Final vision was not affected in 65 (92.9%), whereas 2 (2.9%) and 3 (4.3%) had reduction in visual acuity reduced by ≤3 lines and > 3 lines, respectively. Reported complications included nummular corneal lesions ( n = 1, 1.4%), cystoid macular oedema ( n = 2, 2.9%) and macular scarring ( n = 2, 2.9%). Conclusion Ocular inflammatory events may occur after COVID-19 vaccination. The findings are based on a temporal association that does not prove causality. Even in the possibility of a causal association, most of the events were mild and had a good visual outcome." @default.
• W4206533230 created "2022-01-25" @default.
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• W4206533230 date "2022-01-04" @default.
• W4206533230 modified "2023-10-03" @default.
• W4206533230 title "Ocular inflammatory events following COVID-19 vaccination: a multinational case series" @default.
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• W4206533230 doi "https://doi.org/10.1186/s12348-021-00275-x" @default.
• W4206533230 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34982290" @default.
• W4206533230 hasPublicationYear "2022" @default.
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