FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4206547408> ?p ?o ?g. }

• W4206547408 endingPage "124" @default.
• W4206547408 startingPage "117" @default.
• W4206547408 abstract "Intellectual disability and autism spectrum disorder (ASD) are common, and genetic testing is increasingly performed in individuals with these diagnoses to inform prognosis, refine management and provide information about recurrence risk in the family. For neurogenetic conditions associated with intellectual disability and ASD, data on natural history in adults are scarce; however, as older adults with these disorders are identified, it is becoming clear that some conditions are associated with both neurodevelopmental problems and neurodegeneration. Moreover, emerging evidence indicates that some neurogenetic conditions associated primarily with neurodegeneration also affect neurodevelopment. In this Perspective, we discuss examples of diseases that have developmental and degenerative overlap. We propose that neurogenetic disorders should be studied continually across the lifespan to understand the roles of the affected genes in brain development and maintenance, and to inform strategies for treatment. Traditionally, CNS diseases have been classified into early-onset neurodevelopmental disorders and late-onset neurodegenerative disorders. However, as this article highlights, we now recognize that developmental and neurodegenerative disorders can involve shared mechanisms, with some classic neurodegenerative diseases also having a neurodevelopmental component." @default.
• W4206547408 created "2022-01-26" @default.
• W4206547408 creator A5007635759 @default.
• W4206547408 creator A5008378642 @default.
• W4206547408 creator A5025117011 @default.
• W4206547408 creator A5045361386 @default.
• W4206547408 date "2022-01-05" @default.
• W4206547408 modified "2023-10-14" @default.
• W4206547408 title "Neurogenetic disorders across the lifespan: from aberrant development to degeneration" @default.
• W4206547408 cites W120484358 @default.
• W4206547408 cites W135170103 @default.
• W4206547408 cites W1484723238 @default.
• W4206547408 cites W1562146500 @default.
• W4206547408 cites W1586337846 @default.
• W4206547408 cites W1746907828 @default.
• W4206547408 cites W1885358257 @default.
• W4206547408 cites W1952608303 @default.
• W4206547408 cites W1963598459 @default.
• W4206547408 cites W1965806753 @default.
• W4206547408 cites W1966674056 @default.
• W4206547408 cites W1968900405 @default.
• W4206547408 cites W1969271586 @default.
• W4206547408 cites W1972943699 @default.
• W4206547408 cites W1974743265 @default.
• W4206547408 cites W1981238111 @default.
• W4206547408 cites W1985323612 @default.
• W4206547408 cites W1986503994 @default.
• W4206547408 cites W1991023630 @default.
• W4206547408 cites W1992093172 @default.
• W4206547408 cites W1993023011 @default.
• W4206547408 cites W1993571512 @default.
• W4206547408 cites W1994573232 @default.
• W4206547408 cites W1994922654 @default.
• W4206547408 cites W1997550457 @default.
• W4206547408 cites W1997798496 @default.
• W4206547408 cites W1998245695 @default.
• W4206547408 cites W2002012536 @default.
• W4206547408 cites W2004966039 @default.
• W4206547408 cites W2017062009 @default.
• W4206547408 cites W2018358250 @default.
• W4206547408 cites W2022404993 @default.
• W4206547408 cites W2026086170 @default.
• W4206547408 cites W2026226960 @default.
• W4206547408 cites W2026779731 @default.
• W4206547408 cites W2027601274 @default.
• W4206547408 cites W2034336385 @default.
• W4206547408 cites W2035275418 @default.
• W4206547408 cites W2037075564 @default.
• W4206547408 cites W2041214350 @default.
• W4206547408 cites W2042916026 @default.
• W4206547408 cites W2043323635 @default.
• W4206547408 cites W2045855955 @default.
• W4206547408 cites W2050510668 @default.
• W4206547408 cites W2055308573 @default.
• W4206547408 cites W2055854310 @default.
• W4206547408 cites W2058077186 @default.
• W4206547408 cites W2059221873 @default.
• W4206547408 cites W2060061148 @default.
• W4206547408 cites W2063032803 @default.
• W4206547408 cites W2066724281 @default.
• W4206547408 cites W2070008559 @default.
• W4206547408 cites W2073669413 @default.
• W4206547408 cites W2075141112 @default.
• W4206547408 cites W2076691514 @default.
• W4206547408 cites W2078613475 @default.
• W4206547408 cites W2081067998 @default.
• W4206547408 cites W2082429191 @default.
• W4206547408 cites W2093056142 @default.
• W4206547408 cites W2095860692 @default.
• W4206547408 cites W2096410114 @default.
• W4206547408 cites W2096524612 @default.
• W4206547408 cites W2097936604 @default.
• W4206547408 cites W2100100832 @default.
• W4206547408 cites W2102496376 @default.
• W4206547408 cites W2102979724 @default.
• W4206547408 cites W2103332731 @default.
• W4206547408 cites W2103440561 @default.
• W4206547408 cites W2103739793 @default.
• W4206547408 cites W2107182260 @default.
• W4206547408 cites W2112032347 @default.
• W4206547408 cites W2112957305 @default.
• W4206547408 cites W2113518834 @default.
• W4206547408 cites W2114139156 @default.
• W4206547408 cites W2121642311 @default.
• W4206547408 cites W2126402843 @default.
• W4206547408 cites W2129179498 @default.
• W4206547408 cites W2130272985 @default.
• W4206547408 cites W2130588024 @default.
• W4206547408 cites W2135389676 @default.
• W4206547408 cites W2138660056 @default.
• W4206547408 cites W2142623116 @default.
• W4206547408 cites W2149919973 @default.
• W4206547408 cites W2150873111 @default.
• W4206547408 cites W2152119060 @default.
• W4206547408 cites W2155080244 @default.
• W4206547408 cites W2156044796 @default.
• W4206547408 cites W2157383376 @default.
• W4206547408 cites W2160816909 @default.

• next