Matches in SemOpenAlex for { <https://semopenalex.org/work/W4206605410> ?p ?o ?g. }
- W4206605410 endingPage "137" @default.
- W4206605410 startingPage "137" @default.
- W4206605410 abstract "The continuous vacuum screw filter (CVSF) for small-scale continuous product isolation of suspensions was operated for the first time with cuboid-shaped and needle-shaped particles. These high aspect ratio particles are very common in pharmaceutical manufacturing processes and provide challenges in filtration, washing, and drying processes. Moreover, the flowability decreases and undesired secondary processes of attrition, breakage, and agglomeration may occur intensively. Nevertheless, in this study, it is shown that even cuboid and needle-shaped particles (l-alanine) can be processed within the CVSF preserving the product quality in terms of particle size distribution (PSD) and preventing breakage or attrition effects. A dynamic image analysis-based approach combining axis length distributions (ALDs) with a kernel-density estimator was used for evaluation. This approach was extended with a quantification of the center of mass of the density-weighted ALDs, providing a measure to analyze the preservation of the inlet PSD statistically. Moreover, a targeted residual moisture below 1% could be achieved by adding a drying module (Tdry = 60 °C) to the modular setup of the CVSF." @default.
- W4206605410 created "2022-01-26" @default.
- W4206605410 creator A5007138384 @default.
- W4206605410 creator A5083999455 @default.
- W4206605410 creator A5084002243 @default.
- W4206605410 date "2022-01-19" @default.
- W4206605410 modified "2023-10-13" @default.
- W4206605410 title "Continuous Isolation of Particles with Varying Aspect Ratios up to Thin Needles Achieving Free-Flowing Products" @default.
- W4206605410 cites W2001512736 @default.
- W4206605410 cites W2006340726 @default.
- W4206605410 cites W2010635999 @default.
- W4206605410 cites W2024701089 @default.
- W4206605410 cites W2036601277 @default.
- W4206605410 cites W2041406898 @default.
- W4206605410 cites W2067605265 @default.
- W4206605410 cites W2075594220 @default.
- W4206605410 cites W2093362358 @default.
- W4206605410 cites W2112211764 @default.
- W4206605410 cites W2163987323 @default.
- W4206605410 cites W2269023122 @default.
- W4206605410 cites W2325743067 @default.
- W4206605410 cites W2326690916 @default.
- W4206605410 cites W2337570266 @default.
- W4206605410 cites W2475385728 @default.
- W4206605410 cites W2511348188 @default.
- W4206605410 cites W2591624183 @default.
- W4206605410 cites W2626163103 @default.
- W4206605410 cites W2735305596 @default.
- W4206605410 cites W2798195148 @default.
- W4206605410 cites W2883343212 @default.
- W4206605410 cites W2895975850 @default.
- W4206605410 cites W2896322022 @default.
- W4206605410 cites W2908735786 @default.
- W4206605410 cites W2910981269 @default.
- W4206605410 cites W2986254079 @default.
- W4206605410 cites W3002147917 @default.
- W4206605410 cites W3004895445 @default.
- W4206605410 cites W3013774174 @default.
- W4206605410 cites W3014364308 @default.
- W4206605410 cites W3034901386 @default.
- W4206605410 cites W3092810420 @default.
- W4206605410 cites W3093998636 @default.
- W4206605410 cites W3096098415 @default.
- W4206605410 cites W3097710712 @default.
- W4206605410 cites W3104298728 @default.
- W4206605410 cites W3114767549 @default.
- W4206605410 cites W3126832077 @default.
- W4206605410 cites W3133578585 @default.
- W4206605410 cites W3135514084 @default.
- W4206605410 cites W3162024937 @default.
- W4206605410 cites W3165246804 @default.
- W4206605410 cites W3170726243 @default.
- W4206605410 cites W3205225427 @default.
- W4206605410 cites W4200063406 @default.
- W4206605410 doi "https://doi.org/10.3390/cryst12020137" @default.
- W4206605410 hasPublicationYear "2022" @default.
- W4206605410 type Work @default.
- W4206605410 citedByCount "3" @default.
- W4206605410 countsByYear W42066054102022 @default.
- W4206605410 countsByYear W42066054102023 @default.
- W4206605410 crossrefType "journal-article" @default.
- W4206605410 hasAuthorship W4206605410A5007138384 @default.
- W4206605410 hasAuthorship W4206605410A5083999455 @default.
- W4206605410 hasAuthorship W4206605410A5084002243 @default.
- W4206605410 hasBestOaLocation W42066054101 @default.
- W4206605410 hasConcept C105795698 @default.
- W4206605410 hasConcept C127413603 @default.
- W4206605410 hasConcept C128489963 @default.
- W4206605410 hasConcept C159985019 @default.
- W4206605410 hasConcept C192562407 @default.
- W4206605410 hasConcept C203527163 @default.
- W4206605410 hasConcept C21880701 @default.
- W4206605410 hasConcept C2779015675 @default.
- W4206605410 hasConcept C33923547 @default.
- W4206605410 hasConcept C78519656 @default.
- W4206605410 hasConceptScore W4206605410C105795698 @default.
- W4206605410 hasConceptScore W4206605410C127413603 @default.
- W4206605410 hasConceptScore W4206605410C128489963 @default.
- W4206605410 hasConceptScore W4206605410C159985019 @default.
- W4206605410 hasConceptScore W4206605410C192562407 @default.
- W4206605410 hasConceptScore W4206605410C203527163 @default.
- W4206605410 hasConceptScore W4206605410C21880701 @default.
- W4206605410 hasConceptScore W4206605410C2779015675 @default.
- W4206605410 hasConceptScore W4206605410C33923547 @default.
- W4206605410 hasConceptScore W4206605410C78519656 @default.
- W4206605410 hasIssue "2" @default.
- W4206605410 hasLocation W42066054101 @default.
- W4206605410 hasLocation W42066054102 @default.
- W4206605410 hasOpenAccess W4206605410 @default.
- W4206605410 hasPrimaryLocation W42066054101 @default.
- W4206605410 hasRelatedWork W2082293200 @default.
- W4206605410 hasRelatedWork W2137307547 @default.
- W4206605410 hasRelatedWork W2322085199 @default.
- W4206605410 hasRelatedWork W2380293314 @default.
- W4206605410 hasRelatedWork W2605431086 @default.
- W4206605410 hasRelatedWork W2943188944 @default.
- W4206605410 hasRelatedWork W3008690834 @default.
- W4206605410 hasRelatedWork W3015727542 @default.