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- W4206654168 abstract "Advances in cancer treatment have led to substantial improvements in survival. These include several drugs for treatment of multiple myeloma and metastatic prostate cancer, and immunotherapy with checkpoint inhibitors for treatment of nonsmall cell lung cancer, kidney cancer, melanoma, and others. Management of breast cancer has also changed substantially in the last two decades with approval of CDK4/6 inhibitors, trastuzumab, pertuzumab, TDM1, and other drugs. The pricing of these agents is set by what the market will bear but typically will be more than U.S. $12,000 (~INR 880,000) per month for approved schedules of treatment in the United States, an obscene price that brings huge profits to the pharmaceutical industry. In India, the cost of these therapies is not affordable and only a handful of patients are treated with these medications. There may be some price reduction in other countries, particularly those with a national health service that can bargain for bulk purchase. Some drugs are manufactured and sold in India at a much lower price. However, many effective drugs remain unaffordable for all but the wealthy in lower- and middle-income countries (LMIC) such as India. The majority of people with cancer who could benefit from treatment with new drugs live in LMIC. It is a hollow victory to have generated effective treatments for several types of cancer, but for these therapies, not to be available to the global majority who could benefit. And the nonavailability of life-prolonging treatment is not due to the cost of manufacturing the drugs, it is due to protection of profit at the expense of human life." @default.
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- W4206654168 date "2021-08-10" @default.
- W4206654168 modified "2023-10-16" @default.
- W4206654168 title "Pharmacoeconomics" @default.
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- W4206654168 doi "https://doi.org/10.1055/s-0041-1733826" @default.
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