FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4206688676> ?p ?o ?g. }

• W4206688676 endingPage "11" @default.
• W4206688676 startingPage "3" @default.
• W4206688676 abstract "Introduction Triclofos and melatonin are commonly used oral sedatives in children for obtaining a sleep electroencephalogram (EEG) record. There has been no systematic review till now to compare the efficacy and safety of these two medications. Objectives The review intended to compare the efficacy of oral triclofos and melatonin in children <18 years of age for inducing adequate sedation for obtaining a sleep EEG record. We also attempted to compare the adverse effects, impact on EEG record, the yield of epileptiform abnormalities, and sleep onset latency in both groups. Methods A systematic search was conducted on MEDLINE/PUBMED, Cochrane Central Register of Controlled Trials (CENTRAL), EMBASE, Web of Science, and Google Scholar till November 30, 2020, with the following keywords/the Medical Subject Headings (MESH) terms while searching: sleep EEG, electroencephalogram, triclofos, melatonin OR ramelteon AND epilepsy, seizure, OR convulsion. ROB 2.0 and ROBINS-I tool was used to determine the risk of bias. To assess heterogeneity in studies, Higgins and Thompson's I2 method was utilized. When I2 was more than 50%, a random effects model was utilized and a fixed-effect model was used for other parameters. To assess the presence of publication bias, Egger's test was used. Results For describing the efficacy of triclofos in 1,284 and melatonin in 1,532 children, we selected 16 articles. The indirect comparison between the pooled estimate of all children receiving individual medications revealed comparable efficacy in obtaining successful sleep EEG record with a single dose (90 vs. 76%, p = 0.058) and repeat dose ( p = 0.054), detection of epileptiform abnormalities ( p = 0.06), and sleep onset latency ( p = 0.06), but more proportion of children receiving triclofos had adverse effects ( p = 0.001) and duration of sleep was also higher with triclofos ( p = 0.001). Conclusion Efficacy of triclofos and melatonin are comparable in inducing sleep for recording EEG in children, although triclofos is more likely to cause adverse effects. However, the level of evidence is low for this conclusion and the weak strength of recommendation for the results of this review is likely to change in the future after completion of controlled trials exploring these two medications." @default.
• W4206688676 created "2022-01-25" @default.
• W4206688676 creator A5013830001 @default.
• W4206688676 creator A5014203677 @default.
• W4206688676 creator A5060779793 @default.
• W4206688676 creator A5087002158 @default.
• W4206688676 date "2021-12-30" @default.
• W4206688676 modified "2023-09-27" @default.
• W4206688676 title "Systematic Review and Meta-analysis of Efficacy and Safety of Melatonin and Triclofos for Inducing Adequate Sedation for Sleep Electroencephalogram in Children" @default.
• W4206688676 cites W1973025369 @default.
• W4206688676 cites W2034501514 @default.
• W4206688676 cites W2065934885 @default.
• W4206688676 cites W2083197226 @default.
• W4206688676 cites W2118726049 @default.
• W4206688676 cites W2157788468 @default.
• W4206688676 cites W2171868443 @default.
• W4206688676 cites W2178435360 @default.
• W4206688676 cites W2338124466 @default.
• W4206688676 cites W2482030475 @default.
• W4206688676 cites W2527615523 @default.
• W4206688676 cites W2743689029 @default.
• W4206688676 cites W2884758337 @default.
• W4206688676 cites W2923683345 @default.
• W4206688676 cites W2959193001 @default.
• W4206688676 cites W3120329618 @default.
• W4206688676 cites W3149315047 @default.
• W4206688676 doi "https://doi.org/10.1055/s-0041-1736511" @default.
• W4206688676 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35110915" @default.
• W4206688676 hasPublicationYear "2021" @default.
• W4206688676 type Work @default.
• W4206688676 citedByCount "6" @default.
• W4206688676 countsByYear W42066886762022 @default.
• W4206688676 countsByYear W42066886762023 @default.
• W4206688676 crossrefType "journal-article" @default.
• W4206688676 hasAuthorship W4206688676A5013830001 @default.
• W4206688676 hasAuthorship W4206688676A5014203677 @default.
• W4206688676 hasAuthorship W4206688676A5060779793 @default.
• W4206688676 hasAuthorship W4206688676A5087002158 @default.
• W4206688676 hasBestOaLocation W42066886761 @default.
• W4206688676 hasConcept C118552586 @default.
• W4206688676 hasConcept C126322002 @default.
• W4206688676 hasConcept C1513209611 @default.
• W4206688676 hasConcept C17744445 @default.
• W4206688676 hasConcept C197934379 @default.
• W4206688676 hasConcept C199539241 @default.
• W4206688676 hasConcept C2776478404 @default.
• W4206688676 hasConcept C2776814716 @default.
• W4206688676 hasConcept C2778182776 @default.
• W4206688676 hasConcept C2778186239 @default.
• W4206688676 hasConcept C2779473830 @default.
• W4206688676 hasConcept C2780439572 @default.
• W4206688676 hasConcept C2781053850 @default.
• W4206688676 hasConcept C2781210498 @default.
• W4206688676 hasConcept C42219234 @default.
• W4206688676 hasConcept C522805319 @default.
• W4206688676 hasConcept C71924100 @default.
• W4206688676 hasConcept C95190672 @default.
• W4206688676 hasConceptScore W4206688676C118552586 @default.
• W4206688676 hasConceptScore W4206688676C126322002 @default.
• W4206688676 hasConceptScore W4206688676C1513209611 @default.
• W4206688676 hasConceptScore W4206688676C17744445 @default.
• W4206688676 hasConceptScore W4206688676C197934379 @default.
• W4206688676 hasConceptScore W4206688676C199539241 @default.
• W4206688676 hasConceptScore W4206688676C2776478404 @default.
• W4206688676 hasConceptScore W4206688676C2776814716 @default.
• W4206688676 hasConceptScore W4206688676C2778182776 @default.
• W4206688676 hasConceptScore W4206688676C2778186239 @default.
• W4206688676 hasConceptScore W4206688676C2779473830 @default.
• W4206688676 hasConceptScore W4206688676C2780439572 @default.
• W4206688676 hasConceptScore W4206688676C2781053850 @default.
• W4206688676 hasConceptScore W4206688676C2781210498 @default.
• W4206688676 hasConceptScore W4206688676C42219234 @default.
• W4206688676 hasConceptScore W4206688676C522805319 @default.
• W4206688676 hasConceptScore W4206688676C71924100 @default.
• W4206688676 hasConceptScore W4206688676C95190672 @default.
• W4206688676 hasLocation W42066886761 @default.
• W4206688676 hasLocation W42066886762 @default.
• W4206688676 hasLocation W42066886763 @default.
• W4206688676 hasLocation W42066886764 @default.
• W4206688676 hasOpenAccess W4206688676 @default.
• W4206688676 hasPrimaryLocation W42066886761 @default.
• W4206688676 hasRelatedWork W2392531270 @default.
• W4206688676 hasRelatedWork W2739409155 @default.
• W4206688676 hasRelatedWork W2742455658 @default.
• W4206688676 hasRelatedWork W2990575572 @default.
• W4206688676 hasRelatedWork W3020778149 @default.
• W4206688676 hasRelatedWork W3032587372 @default.
• W4206688676 hasRelatedWork W4200154241 @default.
• W4206688676 hasRelatedWork W4285740326 @default.
• W4206688676 hasRelatedWork W4298144040 @default.
• W4206688676 hasRelatedWork W4309928371 @default.
• W4206688676 hasVolume "13" @default.
• W4206688676 isParatext "false" @default.
• W4206688676 isRetracted "false" @default.
• W4206688676 workType "article" @default.