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- W4206722246 abstract "Staphylococcus aureus is a Gram-positive bacterium that can persist in nature under hostile environmental conditions and interacts with humans as both commensal and pathogen. It is responsible for a multitude of hospital- and community-acquired infections. The bacterium is often found on the skin of the axilla, chest/abdomen, groin, and perineum as well as on the mucosa of pharynx and intestine [1, 2], but the main site of colonization in humans is the vestibulum nasi (anterior nares) [3, 4]. With regard to S. aureus colonization, humans are grouped into three categories: non-carriers, intermittent carriers, and persistent carriers [2]. Around 20% of human population are persistently colonized with S. aureus [5]. Nasal colonization depends on both host and microbial factors that will be described below. The differential rates of colonization among individuals are linked to their immune status, gene polymorphisms, and competition of S. aureus with other microorganisms [2]. Patients with airway diseases, such as asthma or chronic rhinosinusitis with nasal polyps (CRSwNP), show significantly higher rates of S. aureus colonization than healthy adults [6]. It has long been recognized that nasal carriage of S. aureus is a major risk factor for infections, which are mostly caused by the colonizing strain [7]." @default.
- W4206722246 created "2022-01-25" @default.
- W4206722246 creator A5038060687 @default.
- W4206722246 creator A5081073059 @default.
- W4206722246 date "2022-01-01" @default.
- W4206722246 modified "2023-10-18" @default.
- W4206722246 title "Staphylococcus aureus and Its Proteins" @default.
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- W4206722246 doi "https://doi.org/10.1007/978-981-16-0784-4_14" @default.
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