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• W4206730557 abstract "Parkinson's disease (PD), as a manifestation of basal ganglia dysfunction, is associated with a number of speech deficits, including reduced voice modulation and vocal output. Interestingly, previous work has shown that participants with PD show an increased feedback-driven motor response to unexpected fundamental frequency perturbations during speech production, and a heightened ability to detect differences in vocal pitch relative to control participants. Here, we explored one possible contributor to these enhanced responses. We recorded the frequency-following auditory brainstem response (FFR) to repetitions of the speech syllable [da] in PD and control participants. Participants with PD displayed a larger amplitude FFR related to the fundamental frequency of speech stimuli relative to the control group. The current preliminary results suggest the dysfunction of the basal ganglia in PD contributes to the early stage of auditory processing and may reflect one component of a broader sensorimotor processing impairment associated with the disease." @default.
• W4206730557 created "2022-01-26" @default.
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• W4206730557 date "2022-01-19" @default.
• W4206730557 modified "2023-10-06" @default.
• W4206730557 title "Early auditory responses to speech sounds in Parkinson’s disease: preliminary data" @default.
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• W4206730557 doi "https://doi.org/10.1038/s41598-022-05128-8" @default.
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