Matches in SemOpenAlex for { <https://semopenalex.org/work/W4206943926> ?p ?o ?g. }
Showing items 1 to 91 of
91
with 100 items per page.
- W4206943926 endingPage "285" @default.
- W4206943926 startingPage "278" @default.
- W4206943926 abstract "To evaluate the prognostic utility of red blood cell distribution width (RDW) and maximum left ventricular wall thickness (MLVWT) in patients with hypertrophic cardiomyopathy (HCM).This study is a retrospective cohort analysis. Patients diagnosed with HCM at the First Affiliated Hospital of Sun Yat-sen University from March 2014 to March 2019 were included. HCM patients were stratified into two groups based on the occurrence of major adverse cardiac events (MACE). Receiver operating characteristic (ROC) curves were then constructed and Cox regression models were employed to gauge the prognostic relevance of RDW and MLVWT for HCM patients. Kaplan-Meier analysis evaluated the survival and MACE-free rate in patients with different level of RDW and MLVWT.A total of 300 patients with HCM were enrolled in this study and followed up for 40.56±18.33 months. Among them, 117 MACE (39.00%), 40 all-cause deaths (13.33%), and 29 cardiovascular deaths (9.67%). The level of RDW, MLVWT, creatinine (Cr), and B-type pro-brain natriuretic peptide (NT-ProBNP) were statistically different between the MACE group and non-MACE group (P < .05). Multivariate analysis showed that after adjusting for confounding factors, RDW and MLVWT were independent predictors of all-cause mortality and MACE in HCM patients. ROC showed that RDW > .13 and MLVWT > 23 mm are the cut-off value to predict all-cause mortality and MACE. The area under the ROC curve AUC of the combination predicting the occurrence of all-cause mortality and MACE are .823 and .820, respectively. Kaplan-Meier analysis showed that the survival rate and MACE-free survival rate of group 1 (RDW≦.13 and MLVWT≦23 mm) were significantly higher than group 2 (RDW > .13 or MLVWT > 23 mm), and group 3 (RDW > .13 and MLVWT > 23 mm) (P = .000).We determined that increased RDW and MLVWT was independently associated with MACE incidence and risk of mortality in HCM patients. Combined evaluation of RDW and MLVWT yielded a more accurate predictive model of HCM patient outcomes relative to the use of either of these metrics in isolation. Our research can provide a theoretical basis in the occurrence of MACE for the high-risk HCM and intervene them properly and timely." @default.
- W4206943926 created "2022-01-26" @default.
- W4206943926 creator A5043677526 @default.
- W4206943926 creator A5048196237 @default.
- W4206943926 creator A5054798387 @default.
- W4206943926 creator A5061144733 @default.
- W4206943926 creator A5066017671 @default.
- W4206943926 creator A5089486689 @default.
- W4206943926 date "2022-01-23" @default.
- W4206943926 modified "2023-09-30" @default.
- W4206943926 title "Red blood cell distribution width and maximum left ventricular wall thickness predict poor outcomes in patients with hypertrophic cardiomyopathy" @default.
- W4206943926 cites W1995954735 @default.
- W4206943926 cites W1996585245 @default.
- W4206943926 cites W2015706524 @default.
- W4206943926 cites W2017551085 @default.
- W4206943926 cites W2043682727 @default.
- W4206943926 cites W2047581042 @default.
- W4206943926 cites W2052447333 @default.
- W4206943926 cites W2064202773 @default.
- W4206943926 cites W2079307913 @default.
- W4206943926 cites W2097618980 @default.
- W4206943926 cites W2251105674 @default.
- W4206943926 cites W2321185968 @default.
- W4206943926 cites W2328176404 @default.
- W4206943926 cites W2549760673 @default.
- W4206943926 cites W2805684559 @default.
- W4206943926 cites W2954319556 @default.
- W4206943926 cites W2990818353 @default.
- W4206943926 cites W2991546232 @default.
- W4206943926 cites W3000156402 @default.
- W4206943926 cites W3038583342 @default.
- W4206943926 cites W3086702476 @default.
- W4206943926 cites W3157241527 @default.
- W4206943926 cites W3164096065 @default.
- W4206943926 cites W3181207590 @default.
- W4206943926 doi "https://doi.org/10.1111/echo.15303" @default.
- W4206943926 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35066909" @default.
- W4206943926 hasPublicationYear "2022" @default.
- W4206943926 type Work @default.
- W4206943926 citedByCount "1" @default.
- W4206943926 countsByYear W42069439262022 @default.
- W4206943926 crossrefType "journal-article" @default.
- W4206943926 hasAuthorship W4206943926A5043677526 @default.
- W4206943926 hasAuthorship W4206943926A5048196237 @default.
- W4206943926 hasAuthorship W4206943926A5054798387 @default.
- W4206943926 hasAuthorship W4206943926A5061144733 @default.
- W4206943926 hasAuthorship W4206943926A5066017671 @default.
- W4206943926 hasAuthorship W4206943926A5089486689 @default.
- W4206943926 hasConcept C126322002 @default.
- W4206943926 hasConcept C164705383 @default.
- W4206943926 hasConcept C167135981 @default.
- W4206943926 hasConcept C2780185194 @default.
- W4206943926 hasConcept C2780400711 @default.
- W4206943926 hasConcept C2780739214 @default.
- W4206943926 hasConcept C500558357 @default.
- W4206943926 hasConcept C50382708 @default.
- W4206943926 hasConcept C58471807 @default.
- W4206943926 hasConcept C71924100 @default.
- W4206943926 hasConcept C78529466 @default.
- W4206943926 hasConceptScore W4206943926C126322002 @default.
- W4206943926 hasConceptScore W4206943926C164705383 @default.
- W4206943926 hasConceptScore W4206943926C167135981 @default.
- W4206943926 hasConceptScore W4206943926C2780185194 @default.
- W4206943926 hasConceptScore W4206943926C2780400711 @default.
- W4206943926 hasConceptScore W4206943926C2780739214 @default.
- W4206943926 hasConceptScore W4206943926C500558357 @default.
- W4206943926 hasConceptScore W4206943926C50382708 @default.
- W4206943926 hasConceptScore W4206943926C58471807 @default.
- W4206943926 hasConceptScore W4206943926C71924100 @default.
- W4206943926 hasConceptScore W4206943926C78529466 @default.
- W4206943926 hasIssue "2" @default.
- W4206943926 hasLocation W42069439261 @default.
- W4206943926 hasLocation W42069439262 @default.
- W4206943926 hasOpenAccess W4206943926 @default.
- W4206943926 hasPrimaryLocation W42069439261 @default.
- W4206943926 hasRelatedWork W136137370 @default.
- W4206943926 hasRelatedWork W2089715561 @default.
- W4206943926 hasRelatedWork W2258966814 @default.
- W4206943926 hasRelatedWork W2325478293 @default.
- W4206943926 hasRelatedWork W2493322274 @default.
- W4206943926 hasRelatedWork W2638742206 @default.
- W4206943926 hasRelatedWork W2699703797 @default.
- W4206943926 hasRelatedWork W2802485582 @default.
- W4206943926 hasRelatedWork W4294123985 @default.
- W4206943926 hasRelatedWork W4323364654 @default.
- W4206943926 hasVolume "39" @default.
- W4206943926 isParatext "false" @default.
- W4206943926 isRetracted "false" @default.
- W4206943926 workType "article" @default.